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Our top choices for Santa Cruz hotels

Casa Por Temporadas

Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
United States
Cynthia
Casa Por Temporadas

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (373 reviews)
"Got an upgrade for having Expedia status, new rooms are excellent. I understand the older rooms not so much. Easily the nicest place in Santa Cruz."
United States
robert
$131 nightly
The price is $131
May 29 - May 30
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (230 reviews)
"Amazing time"
United States
JORGE
$127 nightly
The price is $127
May 22 - May 23
Marriott Santa Cruz de la Sierra Hotel

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (370 reviews)
"It’s close to the airport and a good spot to rest if you have a long layover. "
United States
Jon
$106 nightly
The price is $106
May 7 - May 8
Sun Hotel

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (426 reviews)
"Good property the great amenities and service"
United States
James
$131 nightly
The price is $131
May 30 - May 31
Camino Real Hotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (97 reviews)
"Great Location"
United States
Blanca
$35 nightly
The price is $35
May 7 - May 8
Premium Suites Deluxe Aparthotel Equipetrol

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (109 reviews)
"Nice place"
United States
Juan Carlos
$55 nightly
The price is $55
May 7 - May 8
Ibis Santa Cruz DE LA Sierra

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (113 reviews)
"REALLY NICE HOTEL. STAFF WONDERFULL"
United States
ERNESTO
$89 nightly
The price is $89
May 23 - May 24
Novotel Santa Cruz De La Sierra

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (63 reviews)
"Clean and close to the malls and restaurants "
United States
Luis
$56 nightly
The price is $56
May 7 - May 8
Chairú Eco Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (270 reviews)
"Convenient location clean rooms good breakfast with a view "
Canada
Jesus Enrique Cabello
$94 nightly
The price is $94
May 13 - May 14
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (101 reviews)
"Place is clean , safe area , walking distance to shops "
United States
Nataly
$27 nightly
The price is $27
May 7 - May 8
Apart Hotel Premium Suites Santa Cruz

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (137 reviews)
"Lovely hotel. Great room, location, staff and amenities. "
Norway
Solvei Emily Brekke
$98 nightly
The price is $98
Jun 6 - Jun 7
Hotel Cortez

Prince Hotel

Prince Hotel
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (4 reviews)
"Nice place "
United States
Marco
$51 nightly
The price is $51
May 20 - May 21
Prince Hotel

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (49 reviews)
"Room was great and staff were very accommodating!"
Canada
David
$57 nightly
The price is $57
May 15 - May 16
HOTEL OSHO

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (88 reviews)
"Rooms are always spotless good breakfasts rooftop pool with decent view "
Canada
Peter
$48 nightly
The price is $48
May 21 - May 22
Delfines Collection Hotel By Mercure

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (43 reviews)
"Beautiful place, wonderful artwork"
United States
Elizabeth
$80 nightly
The price is $80
May 21 - May 22
Alfonsina Hotel Boutique by Inboccaluppo

Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
7.6 out of 10, Good, (7 reviews)
"Very clean room and great staff"
Canada
Stanley
$31 nightly
The price is $31
May 7 - May 8
Hotel Las Américas

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (160 reviews)
"My go too hotel whenever I'm in town! "
United States
Pluetina
$97 nightly
The price is $97
May 7 - May 8
TRYP by Wyndham Santa Cruz

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (205 reviews)
"Nice place to stay"
United States
Ricardo
$38 nightly
The price is $38
May 9 - May 10
Hotel LP Equipetrol

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (87 reviews)
"Beautiful hotel"
Australia
Joanna
$126 nightly
The price is $126
May 21 - May 22
Swissôtel Santa Cruz De La Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Santa Cruz

Showing deals for:May 15 - May 17

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Top Santa Cruz Hotel Reviews

Price trends for hotels in Santa Cruz

Less expensive
More expensive
This month
Next month
March
April
$77
$78
Month
Price
January
$75
February
$72
March
$66
April
$84
May
$77
June
$78
July
$73
August
$75
September
$80
October
$75
November
$77
December
$76
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Santa Cruz. Select dates and complete search for nightly totals inclusive of taxes and fees.

Guide to exploring around Santa Cruz

Top reasons to visit Santa Cruz

  • Cultural Exploration: Santa Cruz boasts a rich cultural scene with various attractions, including cathedrals and notable landmarks.
  • Urban Adventures: The city is perfect for urban exploration, featuring stylish neighborhoods and bustling shopping centers.
  • Outdoor Activities: Visitors can enjoy nearby national parks and excursions, ideal for adventure seekers.
  • Family-Friendly Options: Santa Cruz offers a range of activities suitable for families, ensuring everyone has fun.
  • Diverse Accommodations: From budget hostels to comfortable hotels, there's lodging to fit every traveler's needs.

Find great hotels in Santa Cruz

Explore a variety of hotel accommodations in Santa Cruz, Bolivia, ranging from comfortable hotels to budget-friendly hostels. Whether you're traveling for business, looking for family-friendly options, or seeking pet-friendly experiences, Santa Cruz offers a diverse selection of lodging to suit your needs. Discover the best hotels in the area and enjoy a memorable stay in this vibrant city.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: Los Tajibos is a distinguished 3.5-star hotel that boasts a guest rating of 9.0, offering a unique blend of family-friendly hospitality and modern business amenities. Situated in the heart of Santa Cruz, this hotel is perfect for both leisure and corporate travelers. Families will appreciate the thoughtful amenities, including a First Aid Kit for peace of mind. The lush surroundings and elegant design create a serene atmosphere, making it a perfect retreat after a day of exploring the vibrant city.
  • Marriott Santa Cruz de la Sierra Hotel: A luxurious 5-star establishment, the Marriott Santa Cruz de la Sierra Hotel has earned a guest rating of 9.0, showcasing its commitment to excellence. This hotel is ideal for those seeking a lavish vacation experience, with a focus on family and business needs. With amenities like complimentary cribs for little ones, it ensures that families feel right at home. Its upscale facilities, including an inviting pool and exquisite dining options, make it a top choice for travelers looking to indulge in comfort and style.
  • Hampton by Hilton Santa Cruz/Equipetrol, Bolivia: This 4.5-star hotel shines with a guest rating of 9.2, making it a favored option for families desiring a luxurious stay. Located in the Equipetrol area of Santa Cruz, it offers a range of family amenities, including onsite babysitting services and free cribs. Guests revel in modern, spacious rooms designed for relaxation, alongside a welcoming atmosphere and superior service. Whether you're visiting for leisure or business, this hotel provides a perfect blend of comfort and convenience.

Where to stay in Santa Cruz

Santa Cruz, Bolivia, offers a vibrant mix of culture and urban charm, making it a perfect destination for your vacation. Explore stylish neighborhoods with captivating city views, enjoy sunny weather, and embark on exciting excursions. Discover the tropical vibes and budget-friendly options that cater to families and solo travelers alike. Whether you’re seeking a secluded retreat or a dynamic city experience, Santa Cruz promises an unforgettable getaway filled with rich culture and stunning scenery.

  • Santa Cruz: As the largest city in Bolivia, Santa Cruz is a vibrant hub of culture and commerce. Nestled in the eastern part of the country, it offers a unique blend of modern amenities and traditional charm. Travelers flock to Santa Cruz year-round, especially during peak months like January, July, and September. Here, you can indulge in shopping at bustling malls, explore the beautiful botanical gardens, and visit iconic landmarks such as the picturesque piazza square and the stunning cathedral. The city's diverse culinary scene and lively atmosphere make it an ideal destination for families and culture enthusiasts alike.
  • Samaipata: Located a short drive from Santa Cruz, Samaipata is an enchanting city that beckons outdoor lovers and adventure seekers. With its stunning landscapes and rich history, visitors are drawn to its hiking trails and archaeological sites. Unlike Santa Cruz, Samaipata sees peak visitor numbers in January, July, and September, making it an excellent spot for nature enthusiasts looking for a serene getaway. Highlights include the nearby historic site and breathtaking scenery that allows for immersive experiences in Bolivian nature. The charming town center features local shops and cafes, perfect for unwinding after a day of exploration.
  • Warnes: Just north of Santa Cruz, Warnes is a family-friendly city known for its welcoming atmosphere and outdoor activities. The city sees a surge in visitors during September and the holiday season in December and January. Families can enjoy various resorts and shopping centers, making it an ideal destination for those looking to relax and spend quality time together. Nearby attractions include beautiful botanical gardens and the lively piazza square, where you can soak in the local culture. Warnes combines the vibrancy of city life with the tranquility of nature, ensuring a memorable experience for all visitors.

Things to do in Santa Cruz

Santa Cruz, Bolivia, is a vibrant destination perfect for culture enthusiasts and families alike. Visitors can explore bustling shopping centers and malls, offering a fantastic shopping experience. Additionally, the city features resorts that provide relaxation and leisure options. With its rich culture and diverse activities, Santa Cruz promises an exciting urban adventure for every traveler.

Shopping

In Santa Cruz, visit the Ventura Mall for a variety of international brands and local boutiques. For a more authentic experience, check out the Mercado Nuevo, where you can find handmade crafts and unique souvenirs that reflect the Bolivian culture.

Recreation

Experience rejuvenation at the Los Tajibos Hotel Spa, where you can enjoy soothing massages and holistic treatments. For outdoor relaxation, visit Parque Urbano, featuring walking trails and tranquil spaces to unwind amidst nature's beauty.

Adventure

Explore the stunning Amboró National Park, where you can hike through lush forests, spot diverse wildlife, and enjoy breathtaking views. For a thrilling experience, try zip-lining over the canopy or go mountain biking on rugged trails, perfect for adrenaline seekers looking for excitement in nature.

Nightlife

Experience the vibrant nightlife at Casa de la Cerveza on Av. San Martín, where you can enjoy local brews and delicious tapas. For dancing, head to Club Cielo, known for its lively atmosphere and top DJs spinning all night long.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are June to August, where the prices are slightly lower. This is in comparison to April, September and December, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to customize your preferences, such as your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Santa Cruz hotel reservation with your flights and activities through an Expedia package deal.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, offers a delightful blend of culture, family-friendly activities, and urban exploration. Visitors can enjoy a range of attractions, including national parks, cathedrals, and notable landmarks. Whether you seek cultural immersion, outdoor adventures, or unique experiences, Santa Cruz has something for every traveler, making it an ideal destination for your vacation.

  • Plaza 24 de Septiembre: Experience the vibrant heart of Santa Cruz at Plaza 24 de Septiembre, where you can immerse yourself in local culture among bustling markets, cafes, and beautiful colonial architecture. This lively square is perfect for people-watching and enjoying the city's vibrant atmosphere.
  • Amboró National Park: For nature lovers and adventure seekers, Amboró National Park offers breathtaking scenery and diverse wildlife. Explore its lush trails, stunning waterfalls, and panoramic views for an unforgettable outdoor experience.
  • Blacutt Square: Discover Blacutt Square, a unique landmark that serves as a hub for excursions. It's an ideal starting point for guided tours, showcasing the natural beauty and rich culture of the region.

Best time to go to Santa Cruz

The best time to visit Santa Cruz is dependent on what kind of holiday you are seeking. October is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. June is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.7°C)Light RainMostly SunnySlightly LowAverage
February77.0°F (25.0°C)Light RainMostly CloudySlightly HighAverage
March76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
April74.5°F (23.6°C)Light RainMostly SunnyAverageSlightly High
May70.2°F (21.2°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnyAverageSlightly Low
August72.9°F (22.7°C)No RainSunnySlightly HighSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnyAverageAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageAverage
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowSlightly High

The nearest major airports for your trip to Santa Cruz

Traveling to Santa Cruz, Bolivia, is convenient with its primary airport, Viru Viru International Airport (VVI), situated 10 miles from the city. Notable nearby hotels include the luxurious Marriott Santa Cruz de la Sierra and Radisson Hotel Santa Cruz, both approximately 9 miles from the airport, along with the Novotel Santa Cruz De La Sierra, located 11 miles away. For alternative options, Alcantarí International Airport (SRE) is 164 miles and Chimore Airport (CCA) is 142 miles from Santa Cruz. These hotels offer accessible transportation services to ensure a smooth journey to and from the airport.

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Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from $27 in a few different ways on Expedia. First, key in the dates you'd like to go on vacation, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 72ºF to 88ºF. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from $27 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveler experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Expedia makes booking accommodations in Santa Cruz as simple as swiping right for your dream adventure. First, there's the extensive choice and incredible prices. Then, there's our online Help Center, which operates around-the-clock. Plus, when you become a member of our One Key™ rewards program, you can earn OneKeyCash™* and redeem it on eligible flights, hotels, activities and more. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.