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Compare 300 hotels in Santa Cruz with room rates, reviews, and availability. Most hotels are fully refundable.

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
9.0 out of 10, Wonderful, (195)
"Great hotel, food and location albeit a little expensive "
$103 nightly
The price is $103
Oct 3 - Oct 4
Marriott Santa Cruz de la Sierra Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
9.0 out of 10, Wonderful, (330)
"Los Tajibos is perhaps the best place to stay in Santa Cruz."
$131 nightly
The price is $131
Oct 12 - Oct 13
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (400)
"Great Hotel, had a great time ."
$134 nightly
The price is $134
Oct 1 - Oct 2
Camino Real Hotel

Ibis Santa Cruz DE LA Sierra

3.0 star property
9.6 out of 10, Exceptional, (56)
"Basic hotel with very friendly staff. The staff is superb Very nice neighborhood!!!nice shopping and great restaurants !"
$36 nightly
The price is $36
Sep 29 - Sep 30
Ibis Santa Cruz DE LA Sierra

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (249)
"Nice hotel "
$103 nightly
The price is $103
Oct 3 - Oct 4
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hotel Cortez

3.5 star property
9.0 out of 10, Wonderful, (113)
"The staff and property are second to none! "
$119 nightly
The price is $119
Sep 30 - Oct 1
Hotel Cortez

Sun Hotel

3.5 star property
8.4 out of 10, Very Good, (318)
"Todo excelente "
$97 nightly
The price is $97
Sep 20 - Sep 21
Sun Hotel

Apart Hotel Premium Suites Santa Cruz

3.5 star property
8.6 out of 10, Excellent, (92)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
$27 nightly
The price is $27
Sep 20 - Sep 21
Apart Hotel Premium Suites Santa Cruz

Novotel Santa Cruz De La Sierra

5.0 star property
9.2 out of 10, Wonderful, (97)
"Nice hotel, modern, with pool, good restaurant. Would stay here again without no doubt. "
$89 nightly
The price is $89
Oct 12 - Oct 13
Novotel Santa Cruz De La Sierra

Lido Hotel

3.0 star property
9.0 out of 10, Wonderful, (27)
"Staff is amazing, It is a friendly environment. Our flight was delayed the previous night that we couldn't make it to the hotel and they honored our request. "
$41 nightly
The price is $41
Sep 29 - Sep 30
Lido Hotel

Delfines Collection Hotel By Mercure

3.5 star property
9.0 out of 10, Wonderful, (61)
"Clean comfortable rooms "
$46 nightly
The price is $46
Oct 3 - Oct 4
Delfines Collection Hotel By Mercure

TRYP by Wyndham Santa Cruz

4.0 star property
9.2 out of 10, Wonderful, (132)
"Nice stay with good service "
$87 nightly
The price is $87
Sep 20 - Sep 21
TRYP by Wyndham Santa Cruz

Hotel LP Santa Cruz Centro

3.0 star property
8.0 out of 10, Very Good, (280)
"Clean, friendly staff"
$40 nightly
The price is $40
Sep 25 - Sep 26
Hotel LP Santa Cruz Centro

Hotel LP Equipetrol

3.5 star property
8.2 out of 10, Very Good, (199)
"Nice place to stay"
$46 nightly
The price is $46
Sep 20 - Sep 21
Hotel LP Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
9.0 out of 10, Wonderful, (74)
"Good price, great hotel!"
$47 nightly
The price is $47
Sep 29 - Sep 30
Premium Suites Deluxe Aparthotel Equipetrol

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (79)
"Beautiful hotel"
$118 nightly
The price is $118
Oct 4 - Oct 5
Swissôtel Santa Cruz De La Sierra

Chairú Eco Hotel

3.5 star property
9.4 out of 10, Exceptional, (39)
"Nice and clean hotel "
$51 nightly
The price is $51
Sep 21 - Sep 22
Chairú Eco Hotel

Hotel G

3.5 star property
7.8 out of 10, Good, (104)
"Excelente Hotel "
Hotel G

residencial francia - Hostel

1.0 star property
7.0 out of 10, Good, (4)
"it was average not bad"
$15 nightly
The price is $15
Sep 21 - Sep 22
residencial francia - Hostel

Buganvillas Hotel Suites & Spa

4.0 star property
7.4 out of 10, Good, (92)
"Gammelt og veldig slitt og skittent. Det var et fint hotell for 20 år siden. Men ikke vedlikeholdt. "
Buganvillas Hotel Suites & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Santa Cruz

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Top Santa Cruz Hotel Reviews

Price trends for hotels in Santa Cruz

Price trends for hotels in Santa Cruz

Less expensive
More expensive
Next month
August
September
$74
Month
Price
January
$69
February
$68
March
$69
April
$69
May
$75
June
$63
July
$63
August
$53
September
$78
October
$74
November
$78
December
$72
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Santa Cruz. Select dates and complete search for nightly totals inclusive of taxes and fees.

Guide to exploring around Santa Cruz

Guide to exploring around Santa Cruz

Top reasons to visit Santa Cruz

  • Outdoor Adventures: Santa Cruz is a paradise for outdoor enthusiasts, offering access to national parks and stunning natural landscapes.
  • Vibrant Culture: Experience rich cultural heritage through historical landmarks, local customs, and traditional festivities.
  • Luxurious Accommodations: Choose from a variety of lodging options, including luxurious hotels and cozy hostels that suit all types of travelers.
  • Shopping and Dining: Explore vibrant shopping malls and local boutiques, along with a diverse culinary scene.
  • Perfect Weather: Enjoy sunny, tropical weather that enhances outdoor activities and exploration.

Find great hotels in Santa Cruz

Discover a range of hotel accommodations in Santa Cruz, Bolivia, ideal for every type of traveler. Whether you're seeking a business-friendly environment, a family getaway, or a pet-friendly retreat, you'll find options that cater to your needs. From luxurious star-rated hotels to cozy hostels, Santa Cruz offers diverse lodging choices to make your stay memorable.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: Experience a harmonious blend of comfort and sophistication at Los Tajibos, a centrally located hotel ideal for both business and family travelers. This 3.5-star property features a range of business amenities, including accessible meeting rooms and conference spaces, making it a great choice for corporate stays. Families will appreciate the dedicated children's amenities, such as a child-friendly pool and first aid services. The hotel's prime location in the heart of Santa Cruz allows guests to easily explore the city's vibrant culture and attractions.
  • Hotel G: Embrace a pet-friendly atmosphere at Hotel G, a delightful 3.5-star retreat where furry friends are welcome. This charming hotel allows pets onsite, catering to travelers who wish to bring their beloved animals along for the adventure. Whether you're in town for leisure or business, the welcoming ambiance and laid-back vibe ensure a comfortable stay. The hotel's pet policies and amenities, including services for dogs and cats, make it a perfect choice for animal lovers seeking a home away from home.
  • Hampton by Hilton Santa Cruz/Equipetrol, Bolivia: Discover luxury and inclusivity at Hampton by Hilton, a 4.5-star hotel that warmly welcomes families and the LGBTQIA community. This upscale property boasts a variety of family-friendly services, including onsite babysitting and complimentary cribs, ensuring a stress-free stay for parents. With its modern design and commitment to exceptional service, guests can unwind in style. The hotel's affiliation with LGBTQI travel guides highlights its dedication to creating a safe and welcoming environment for all travelers, making it an excellent choice for your Santa Cruz getaway.

Where to stay in Santa Cruz

Santa Cruz, Bolivia, offers a vibrant mix of outdoor adventures and rich cultural experiences. Explore stylish getaways with stunning city views and indulge in the tropical atmosphere. Whether you're seeking secluded beaches or family-friendly excursions, you'll find the best places to relax and immerse yourself in local culture. Enjoy the sunny weather as you discover the hidden gems of this beautiful region, making your vacation truly unforgettable.

  • Santa Cruz: As the largest city in Bolivia, Santa Cruz serves as the vibrant heartbeat of the region. Nestled in the eastern part of the country, this city attracts visitors year-round with its mix of urban charm and outdoor adventures. The city's traveler numbers peak during January, July, and September, drawing families and adventure seekers alike. You can enjoy a variety of activities such as shopping at local malls, exploring the botanical garden, or catching a game at a sports facility. Don't miss the picturesque Piazza Square, where you can immerse yourself in the local culture and enjoy street performances.
  • Samaipata: Located about 120 kilometers from Santa Cruz, Samaipata is a hidden gem for nature lovers and adventure seekers. This charming town is renowned for its stunning landscapes and outdoor activities, especially hiking along scenic trails. It experiences a peak in visitors during January, July, and September, with a slightly lower influx in May and late October to November. Explore the local market for authentic artisanal goods and relax in one of the inviting resorts. The nearby archaeological site is a must-visit, showcasing the historical significance of the area and offering a glimpse into Bolivia's rich past.
  • San Jose de Chiquitos: Situated further east of Santa Cruz, San Jose de Chiquitos is a cultural haven famous for its remarkable Jesuit missions and historical architecture. This city attracts travelers seeking adventure and cultural experiences, with peak visits in April, July, and September. Explore the stunning churches and places of worship, which reflect the area’s rich heritage. The ambiance here is unique, offering a blend of outdoor exploration and cultural immersion. Don't forget to visit the local historic sites to gain insight into the fascinating history that shaped this region.

Things to do in Santa Cruz

Santa Cruz offers a perfect blend of outdoor adventures and cultural experiences for family vacations. Visitors can enjoy luxurious resorts, explore vibrant shopping mall centers, and discover local boutiques. The city's lively atmosphere and diverse activities make it an ideal destination for tourists seeking both relaxation and excitement.

Shopping

In Santa Cruz, explore Ventura Mall for a vibrant shopping experience with entertainment and family-friendly vibes. Las Brisas Shopping Center offers a mix of shops and dining, while Warnes Plaza combines shopping with local culture, making it perfect for finding unique gifts and souvenirs.

Recreation

At Ramon Tahuichi Aguilera Stadium, immerse yourself in a vibrant sports atmosphere. Engage in recreational activities, witness local events, and feel the energy of the crowd. This venue offers a unique way to experience the local culture while staying active and enjoying the lively spirit of Santa Cruz.

Adventure

Explore Amboró National Park, a biodiverse wonderland offering hiking trails through lush jungles and stunning waterfalls. For adrenaline junkies, try zip-lining over the tree canopy. Visit the Lomas de Arena for sandboarding on towering dunes, an exhilarating experience that combines adventure with breathtaking views of the surrounding landscapes.

Nightlife

In Santa Cruz, Cine Center offers a cozy cinema experience perfect for a romantic night out, while Casa Municipal de Cultura Raúl Otero Reiche showcases captivating performances in a vibrant cultural setting, making it ideal for family entertainment and cultural immersion.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

To save money on your trip to Santa Cruz, Bolivia, consider visiting during the cheaper months of June, August, and November, avoiding the pricier periods of March to April and September. Saturday is the least expensive day to book your stay, while Tuesday is the most costly. Use Expedia to compare hotel rates, filter for eco-friendly options, and secure package deals that combine flights and accommodations. Joining Expedia's One Key membership can also provide exclusive discounts and the chance to earn cash for future bookings. Additionally, explore free local attractions to maximize your savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are June, August and November, where the prices are slightly lower. This is in comparison to March to April and September, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday.
  • Find cheap hotels on Expedia: Expedia's search feature lets you set your budget, choose your desired location, and much more. You can sort your results to display prices from lowest to highest, making it easy to find the most affordable hotels right away. Additionally, you can refine your search by hotel type—if you select the Eco-certified filter, you'll see a list of sustainable and environmentally-friendly hotels that you can book.
  • Consider bundling your trip: You can save money by combining your Santa Cruz hotel reservation with your flights and activities by choosing an Expedia package.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, is the perfect destination for outdoor enthusiasts and culture lovers alike, offering a memorable family vacation. Visitors can explore national parks, stunning cathedrals, and local landmarks that highlight the region's rich culture and adventurous spirit. With activities suitable for all ages, your time in Santa Cruz promises to be filled with engaging experiences that capture the essence of this vibrant city.

  • Plaza 24 de Septiembre: This vibrant square is the heart of Santa Cruz, bustling with local culture and city life. Enjoy people-watching, local markets, and beautiful colonial architecture that reflect the city’s rich history.
  • Amboró National Park: An outdoor paradise, this national park offers breathtaking scenery and thrilling adventures. Explore diverse ecosystems, hike through lush forests, and spot unique wildlife, making it a must-visit for nature enthusiasts.
  • Blacutt Square: A significant landmark in Santa Cruz, Blacutt Square is perfect for excursions. Experience local events or relax in a serene environment surrounded by historical significance and charming architecture.

Best time to go to Santa Cruz

The best time to visit Santa Cruz is dependent on what kind of holiday you are seeking. October is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. June is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.700000000000003°C)Light RainMostly SunnySlightly LowAverage
February77.0°F (25.0°C)Light RainMostly CloudySlightly HighAverage
March76.5°F (24.700000000000003°C)Light RainMostly SunnyAverageSlightly High
April74.5°F (23.6°C)Light RainMostly SunnyAverageSlightly High
May70.2°F (21.200000000000003°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnyAverageAverage
August72.9°F (22.700000000000003°C)No RainSunnySlightly HighSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnyAverageAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageSlightly Low
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowAverage

The nearest major airports for your trip to Santa Cruz

When visiting Santa Cruz, Bolivia, the major airport to fly into is Viru Viru International Airport (VVI), situated 10 miles from the city. Notable hotels nearby include the 5-star Marriott Santa Cruz de la Sierra and Radisson Hotel Santa Cruz, both 9 miles away, as well as the Novotel Santa Cruz De La Sierra, located 11 miles from VVI. For additional options, travelers might consider flying into Potosi (POI), 206 miles away, with hotel choices like Coloso Potosi and Hotel Santa Monica, both 4 miles from the airport. Transportation services to these hotels often include airport shuttles available on request.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from $15 in a few different ways on Expedia. First, key in the dates you'd like to go on vacation, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 72ºF to 88ºF. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from $15 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveler experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Expedia makes booking accommodations in Santa Cruz as simple as swiping right for your dream adventure. First, there's the extensive choice and incredible prices. Then, there's our online Help Center, which operates around-the-clock. Plus, when you become a member of our One Key™ rewards program, you can earn OneKeyCash™* and redeem it on eligible flights, hotels, activities and more. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.