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Cheap Flights to Santo Tomé Department from $57

View $57 flight on Mon, Nov 23, 2026Opens in a new window

Popular airlines to Santo Tomé Department

  • Aerolineas Argentinas

  • GOL Linhas Aereas S.A.

  • B & H Airlines

  • LATAM Airlines Group

  • Air France

  • KLM

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How much is the cheapest flight to Santo Tomé Department?

Prices were available within the past 7 days and start at $57 for one-way flights and $130 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Sun, Dec 6 - Thu, Dec 31
AEP
Buenos Aires
PSS
Posadas
$130 Roundtrip, found 1 day ago
$130
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Sun, Dec 6 from Buenos Aires to Posadas, returning Thu, Dec 31, priced at $130 found 1 day ago
Jetsmart SPA
Mon, Dec 14 - Wed, Dec 16
AEP
Buenos Aires
PSS
Posadas
$151 Roundtrip, found 13 hours ago
$151
Roundtrip
found 13 hours ago
Select Jetsmart SPA flight, departing Mon, Dec 14 from Buenos Aires to Posadas, returning Wed, Dec 16, priced at $151 found 13 hours ago
Jetsmart SPA
Wed, Dec 2 - Tue, Dec 8
AEP
Buenos Aires
PSS
Posadas
$158 Roundtrip, found 7 hours ago
$158
Roundtrip
found 7 hours ago
Select Jetsmart SPA flight, departing Wed, Dec 2 from Buenos Aires to Posadas, returning Tue, Dec 8, priced at $158 found 7 hours ago
Jetsmart SPA
Tue, Nov 17 - Fri, Nov 20
AEP
Buenos Aires
PSS
Posadas
$159 Roundtrip, found 12 hours ago
$159
Roundtrip
found 12 hours ago
Select Jetsmart SPA flight, departing Tue, Nov 17 from Buenos Aires to Posadas, returning Fri, Nov 20, priced at $159 found 12 hours ago
Jetsmart SPA
Sat, Dec 19 - Mon, Dec 28
AEP
Buenos Aires
PSS
Posadas
$165 Roundtrip, found 5 days ago
$165
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Sat, Dec 19 from Buenos Aires to Posadas, returning Mon, Dec 28, priced at $165 found 5 days ago
Jetsmart SPA
Sat, Dec 19 - Sun, Jan 3
AEP
Buenos Aires
PSS
Posadas
$174 Roundtrip, found 5 days ago
$174
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Sat, Dec 19 from Buenos Aires to Posadas, returning Sun, Jan 3, priced at $174 found 5 days ago
Aerolineas Argentinas
Mon, Aug 24 - Tue, Sep 1
EZE
Buenos Aires
PSS
Posadas
$254 Roundtrip, found 11 hours ago
$254
Roundtrip
found 11 hours ago
Select Aerolineas Argentinas flight, departing Mon, Aug 24 from Buenos Aires to Posadas, returning Tue, Sep 1, priced at $254 found 11 hours ago
GOL Linhas Aereas S.A.
Thu, Aug 13 - Sat, Aug 29
IGU
Foz do Iguaçu
PSS
Posadas
$896 Roundtrip, found 9 hours ago
$896
Roundtrip
found 9 hours ago
Select GOL Linhas Aereas S.A. flight, departing Thu, Aug 13 from Foz do Iguaçu to Posadas, returning Sat, Aug 29, priced at $896 found 9 hours ago
LATAM Airlines Group
Wed, Sep 2 - Sun, Sep 6
GYE
Guayaquil
PSS
Posadas
$916 Roundtrip, found 16 hours ago
$916
Roundtrip
found 16 hours ago
Select LATAM Airlines Group flight, departing Wed, Sep 2 from Guayaquil to Posadas, returning Sun, Sep 6, priced at $916 found 16 hours ago
avianca
Tue, Sep 1 - Sun, Sep 6
SJO
San José
PSS
Posadas
$931 Roundtrip, found 13 hours ago
$931
Roundtrip
found 13 hours ago
Select avianca flight, departing Tue, Sep 1 from San José to Posadas, returning Sun, Sep 6, priced at $931 found 13 hours ago

Trending flights to Santo Tomé Department

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aerolineas Argentinas
Thu, Aug 13 - Thu, Aug 20
MIA
Miami
PSS
Posadas
$1,239 Roundtrip, found 11 hours ago
$1,239
Roundtrip
found 11 hours ago
Select Aerolineas Argentinas flight, departing Thu, Aug 13 from Miami to Posadas, returning Thu, Aug 20, priced at $1,239 found 11 hours ago

Frequently asked questions

How do I find cheap flights to Santo Tomé Department that have flexible change policies?
At Expedia, we've been channeling our inner yoga master to provide you with the most flexible fares available. Simply check the "No change fee" box directly under the filter subheading "Flexible change policies" to find your dream flight to Santo Tomé Department.
How can I find cheap tickets to Santo Tomé Department?
You'll always find an amazing deal with Expedia, but our "flexible dates" feature makes it that much easier. Enter your preferred flight date, then click on the flexible dates box above to compare prices for nearby days. $130 was the lowest price for a flight to Santo Tomé Department in the last seven days.
How much is a flight to Santo Tomé Department?
If you were jetting one way from Buenos Aires (AEP), you could've scored a cheap seat for just $57 in the last seven days. Return flights to Santo Tomé Department ranged from only $130 to $1,239 over the same period.
When is the cheapest time to fly to Santo Tomé Department?
Consider jetting off early on in the week to secure the best fare to Santo Tomé Department. Tuesday is routinely the most affordable day to fly, followed by Monday. Saturday typically has the most expensive prices. This is because many people prefer to begin their trip on a weekend.
How much is a plane ticket to Santo Tomé Department?
In the last seven days, tickets to Santo Tomé Department varied from $130 to $1,239.
What months are the cheapest to book a flight to Santo Tomé Department?
February is a cheap month to lock in a seat for your Santo Tomé Department adventure. Airfares are at their most expensive throughout the busy month of December, so keep clear of this time if you can.

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Travel information

*Flight schedules are subject to change.

*Available to One Key members.

 

*Flight schedules are subject to change.

*Available to One Key members.