Downtown San Luis Obispo Vacations from $464

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Downtown San Luis Obispo Vacation

A well-liked leafy neighborhood, Downtown San Luis Obispo tempts visitors with its distilleries and craft breweries, markets and shopping. Lock in a vacation package to Downtown San Luis Obispo and experience all of those highlights and more. Kick off your trip to Downtown San Luis Obispo by checking out nearby attractions such as Mission San Luis Obispo de Tolosa, California Polytechnic State University, San Luis Obispo and Fremont Theater. Don't just wish for it — turn it into reality! Reserve your ultimate Downtown San Luis Obispo vacation with Expedia and get to where you're going your way.

The Latest Downtown San Luis Obispo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Sea Air Inn & Suites - Downtown - Restaurant Row
Stables Inn
Victorian Manor In Paso Robles Wine Country + Pool, Hot Tub, Firepit, Tennis Court Sleeps 28
Blufftop Inn & Suites - Wharf/Restaurant District
Wellsona Vineyard Retreat + Pool, Hot Tub, Views Main Home + Guest Home

Where to stay in Downtown San Luis Obispo

Find the best Downtown San Luis Obispo areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Luis Obispo

Downtown San Luis Obispo Hotel Deals

Hotel San Luis Obispo

Hotel San Luis Obispo

4.5 out of 5
877 Palm Street, San Luis Obispo, CA
Fully refundableReserve now, pay when you stay
$386 nightly
The price is $438 total per night from Sep 1 to Sep 2
$438 total
Sep 1 - Sep 2
Total with taxes and fees
Hotel San Luis Obispo
SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

3.5 out of 5
2241 Price Street, Pismo Beach, CA
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $205 total per night from Sep 1 to Sep 2
$205 total
Sep 1 - Sep 2
Total with taxes and fees
SeaCrest OceanFront Hotel
Spyglass Inn

Spyglass Inn

3 out of 5
2705 Spyglass Dr, Pismo Beach, CA
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $188 total per night from Sep 22 to Sep 23
$188 total
Sep 22 - Sep 23
Total with taxes and fees
8.8/10 Excellent! (1,178 reviews)
"Heather was a friendly front office girl. Comfortable room with beautiful view of the ocean. Great scenic walking path. Beautiful sunset from our patio."

Reviewed on Aug 28, 2025

Spyglass Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Downtown San Luis Obispo

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.