Find hotels near Dupree Nature Preserve, Lancaster from $54

Start date: Check-in selected.
To Date
End date: Check-out

Check prices for these dates

Tonight
Dec 8 - Dec 9
Tomorrow
Dec 9 - Dec 10
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Filter by

Guest rating
Guest rating
Star rating

Compare 1,243 hotels close to Dupree Nature Preserve with room rates, reviews, and availability. Most hotels are fully refundable.

Premium Single Room, 1 King Bed, Non Smoking | Individually decorated, individually furnished, desk, blackout drapes
Shaker Village of Pleasant Hill

Shaker Village of Pleasant Hill

3.5 star property
4.9 mi from Dupree Nature Preserve
9.4 out of 10, Exceptional, (451)
"Just click book now button. Very cool place to stay!!!"
United States
Drew
$132 nightly
The price is $145
Dec 15 - Dec 16
Total with taxes and fees
Shaker Village of Pleasant Hill
Lobby
Comfort Inn Lexington South

Comfort Inn Lexington South

2.5 star property
4.4 mi from Dupree Nature Preserve
8.2 out of 10, Very Good, (611)
"We’ve stayed there a couple times. Always clean, friendly and breakfast is on time "
United States
Edward
$72 nightly
The price is $80
Dec 21 - Dec 22
Total with taxes and fees
Comfort Inn Lexington South
Exterior
Holiday Inn Express Nicholasville by IHG

Holiday Inn Express Nicholasville by IHG

2.5 star property
8.3 mi from Dupree Nature Preserve
8.8 out of 10, Excellent, (600)
"Kristin was amazing!!! We loved her she was so helpful and always so friendly! "
United States
Regina
$83 nightly
The price is $92
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Express Nicholasville by IHG
Standard Room, 2 Queen Beds, Non Smoking | Desk, free WiFi, bed sheets
Derby Inn & Suites

Derby Inn & Suites

2.5 star property
9.5 mi from Dupree Nature Preserve
6.8 out of 10, (247)
"Pet friendly as well"
United States
Jere
$67 nightly
The price is $74
Dec 9 - Dec 10
Total with taxes and fees
Derby Inn & Suites
Terrace/patio
Hampton Inn Nicholasville Brannon Crossing

Hampton Inn Nicholasville Brannon Crossing

2.5 star property
12.5 mi from Dupree Nature Preserve
9.4 out of 10, Exceptional, (235)
"Excellent staff wonderful stay"
United States
Tim
$87 nightly
The price is $96
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn Nicholasville Brannon Crossing
Free daily buffet breakfast
Quality Inn Harrodsburg

Quality Inn Harrodsburg

2.5 star property
10.6 mi from Dupree Nature Preserve
7.6 out of 10, Good, (53)
"Nice place to stay"
United States
Dennis Ray
$49 nightly
The price is $54
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Inn Harrodsburg
Exterior
Clarion Pointe Harrodsburg-Danville

Clarion Pointe Harrodsburg-Danville

2.5 star property
10.6 mi from Dupree Nature Preserve
7.2 out of 10, Good, (553)
"Great staff, comfortable beds and a tv that’s not too small for the room. "
United States
Denise
$70 nightly
The price is $77
Jan 4 - Jan 5, 2026
Total with taxes and fees
Clarion Pointe Harrodsburg-Danville
Comfort Loft, Lake View | Terrace/patio
LockRidge Park

LockRidge Park

2.5 star property
8.7 mi from Dupree Nature Preserve
8.0 out of 10, Very Good, (2)
"Need a quick getaway for a client of ours had a wonderful experience"
United States
Brian
$145 nightly
The price is $155
Dec 12 - Dec 13
Total with taxes and fees
LockRidge Park
Property entrance
The Gate House

The Gate House

3.0 star property
13 mi from Dupree Nature Preserve
7.4 out of 10, Good, (11)
"The property is an older home very beautifully done. I would definitely stay there again by myself or with family/"
United States
Mayra
$99 nightly
The price is $106
Dec 9 - Dec 10
Total with taxes and fees
The Gate House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Dupree Nature Preserve Hotel Reviews

Elwood Hotel & Suites

Elwood Hotel & Suites

10/10 Excellent
"This hotel is a gem! Large clean spacious room. We really enjoyed staying here. The staff were all so nice and took excellent care of all our needs. We would definitely recommend it!!"
Pat 1-night trip
Posted 9 hours ago
Elwood Hotel & Suites

Hotels near other Dupree Nature Preserve attractions

Tom Dorman State Nature Preserve

Tom Dorman State Nature Preserve is just one of the places to see in Lancaster, so why not enjoy the other things to explore during your travels? Take in the theater scene while you're in the area.
See properties

Crutcher Nature Preserve

After visiting Crutcher Nature Preserve, make a plan to see the other sights and activities in Lancaster. Take in the theater scene while you're in the area.
See properties

Frequently asked questions

What's the area like around Dupree Nature Preserve?
Dupree Nature Preserve is located in Lancaster. You'll find 24 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Dupree Nature Preserve?
Holiday Inn Express Nicholasville by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. You'll find it 8.3 mi (13.3 km) from Dupree Nature Preserve. Other good choices in the area include Origin Lexington a Wyndham Hotel and Hampton Inn Nicholasville Brannon Crossing.
How many hotels can I expect to find near Dupree Nature Preserve?
Expedia has 24 hotels and other accommodations a few miles from Dupree Nature Preserve.
If I need to cancel the hotel reservation for my stay near Dupree Nature Preserve, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to review top deals close to Dupree Nature Preserve.
Where can I learn more about changing or cancelling my trip in the area near Dupree Nature Preserve?
For more details about picking new dates or cancelling your stay near Dupree Nature Preserve, go to https://www.expedia.com/service/.
What can I see and do near Dupree Nature Preserve?
Sights like Camp Nelson National Monument and Shaker Village of Pleasant Hill highlight some of the local culture. Peninsula Golf Course, Jessamine Creek Gorge Preserve, and Jim Beam Nature Preserve are worth a stop while you're in the area. Asbury University and Asbury Theological Seminary are some sights worth a visit in the area.