East End Vacations from $671

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The Latest East End Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

Save 100% on your flight
$671
per person
Oct 29 - Nov 2
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Fort Myers (RSW)
8.6/10 Excellent! (1,005 reviews)
The Perry Hotel Naples

The Perry Hotel Naples

Save 100% on your flight
$811
per person
Dec 1 - Dec 5
found 24 hours ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.6/10 Exceptional! (1,099 reviews)
The hotel is new. Rooms are very spacious. Hotel pool is cute, although small. The boat ride to the beach is a nice touch but keep in mind you must reserve ahead of time. Having the coffee shop in the lobby was convenient. The location is a bit weird behind a small shopping center.

Reviewed on Sep 26, 2026

Mariners Boathouse by Coolvacay

Mariners Boathouse by Coolvacay

South Island
Save 100% on your flight
$1,005
per person
Nov 28 - Dec 4
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.8/10 Exceptional! (13 reviews)
Very nice place, our 2nd time here and we still love it

Reviewed on Sep 7, 2026

Wiggins Pass Chalet

Wiggins Pass Chalet

Save 100% on your flight
$873
per person
Dec 1 - Dec 8
found 24 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Fort Myers (RSW)
9.6/10 Exceptional! (285 reviews)
LaPlaya Beach & Golf Resort - A Noble House Resort

LaPlaya Beach & Golf Resort - A Noble House Resort

Vanderbilt Beach
Save 100% on your flight
$2,088
per person
Dec 1 - Dec 8
found 24 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Fort Myers (RSW)
9/10 Wonderful! (1,008 reviews)

Where to stay in East End

Find the best East End areas and neighborhoods for the activities you enjoy most. Learn more about East End
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

3 out of top 10 points of interest in this area

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

A coastal scene with a lighthouse, beach, and ocean.

West End

3 out of top 10 points of interest in this area

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

A cyclist on a paved path alongside a road with cars, palm trees, and a liquor store sign.

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

A beach with a green umbrella and two lounge chairs.

Gulf Shores

While there might not be top attractions in Gulf Shores, you can explore the larger area and discover places like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge.

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Sanctuary

While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach.

East End Hotel Deals

Sanibel Inn

Sanibel Inn

937 East Gulf Drive Sanibel FL
Fully refundableReserve now, pay when you stay
$407 nightly
$448 total
Sep 30 - Oct 1
Total with taxes and fees
9.2/10 Wonderful! (1,002 reviews)
"We had an amazing time at The Sanibel Inn. From the front desk staff to the bar tenders and on site property managers we give it a 10/10. The rooms were very clean and staff came in daily to bring clean towels and make the bed etc. The property is extremely well maintained and clean. The bikes were ..."

Reviewed on Sep 25, 2026

Sanibel Inn
coastal chic, new glow up and across the street from beach! Spring Savings

coastal chic, new glow up and across the street from beach! Spring Savings

Sanibel FL
$459 nightly
$477 total
Sep 27 - Sep 28
Total with taxes and fees
9/10 Wonderful! (43 reviews)
"Very close to the beach. Had a great trip as this is our third time staying here."

Reviewed on Aug 1, 2026

coastal chic, new glow up and across the street from beach! Spring Savings
Amazing Direct Ocean Gulf Front Beach Views Condo, pool and hot tub are open!

Amazing Direct Ocean Gulf Front Beach Views Condo, pool and hot tub are open!

Sanibel FL
9.8/10 Exceptional! (208 reviews)
"Property was clean and in a great location.The host was easy to contact and made every effort to make our stay enjoyable.Hope to come back again soon!"

Reviewed on Sep 8, 2026

Get rates
Amazing Direct Ocean Gulf Front Beach Views Condo, pool and hot tub are open!
See all 619 properties in East End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular East End attractions

Sanibel Island Lighthouse

9.0/10 (2,254 reviews)
Although nobody knows how many shipwrecks it’s prevented, this lighthouse has been a welcome beacon for over a century. Visit it on an island that’s noted for shell collecting.
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Sanibel Island Northern Beach

9.4/10 (292 reviews)
Why not spend a lazy afternoon at Sanibel Island Northern Beach during your trip to Sanibel?
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Sanibel and Captiva Island Visitor's Center

9.0/10 (248 reviews)
Sanibel and Captiva Island Visitor's Center is just one of the places to see in Sanibel, so why not enjoy the other things to explore during your travels? Stroll along the seaside or discover the beautiful sunsets in this family-friendly area.
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Sanibel and Captiva Chamber of Commerce and Visitors Center

9.0/10 (6 reviews)
Sanibel and Captiva Chamber of Commerce and Visitors Center is just one of the places to see in Sanibel, so why not enjoy the other things to explore during your travels? Wander the beautiful beaches and seaside in this family-friendly area.
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Sanibel Sea School

8.0/10 (1 review)
You can take time to visit Sanibel Sea School during your travels to Sanibel. Wander the beautiful beaches and seaside in this family-friendly area.
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Sanibel Moorings Botanical Gardens

8.4/10 (42 reviews)
Enjoy the beautiful sunsets and explore Sanibel Moorings Botanical Gardens, a lovely green space in Sanibel. Wander the beautiful beaches and seaside in this family-friendly area.
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Things to do

Fort Myers Beach Sunset and Dolphin Watching Cruise

Fort Myers Beach Sunset and Dolphin Watching Cruise

$70
per adult
100% of travellers recommend
Fort Myers Beach Sunset and Dolphin Watching Cruise
Copacetic Day Sail

Copacetic Day Sail

$70
per adult
100% of travellers recommend
Copacetic Day Sail
Southwest Florida Sunset Sail

Southwest Florida Sunset Sail

$70
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
See all activities in Sanibel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.