East Florence Vacations from $689

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Your East Florence Vacation

Leap into your next big adventure with one of our East Florence vacation packages. Spend your days getting to know this neighborhood's countless delights, including its festivals. Your trip to East Florence wouldn't be complete without stopping by big-name attractions nearby such as University of North Alabama, Renaissance Tower and Kennedy-Douglass Center for the Arts. Whatever your ideal East Florence vacation looks like, you can turn it into reality with Expedia.

The Latest East Florence Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Lake View Inn & Suites

Lake View Inn & Suites

$689
per person
Sep 25 - Sep 27
found 3 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Muscle Shoals (MSL)
5.4/10 (275 reviews)
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

$925
per person
Sep 11 - Sep 14
found 24 hours ago
Roundtrip non-stop flight included
San Francisco (SFO) to Muscle Shoals (MSL)
9/10 Wonderful! (635 reviews)
Very comfortable and well maintained facility

Reviewed on Aug 2, 2026

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

$908
per person
Sep 11 - Sep 14
found 24 hours ago
Roundtrip non-stop flight included
San Francisco (SFO) to Muscle Shoals (MSL)
9/10 Wonderful! (668 reviews)
We always stay here when we come to Tuscumbia. If there’s any improvements to be made it would be on the protein offering at breakfast.

Reviewed on Aug 5, 2026

Best Western Plus Russellville Hotel & Suites

Best Western Plus Russellville Hotel & Suites

$736
per person
Sep 25 - Sep 27
found 3 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Muscle Shoals (MSL)
8.8/10 Excellent! (508 reviews)
Econo Lodge Russellville

Econo Lodge Russellville

$833
per person
Sep 11 - Sep 14
found 24 hours ago
Roundtrip non-stop flight included
San Francisco (SFO) to Muscle Shoals (MSL)
7.4/10 Good! (143 reviews)
Bueno

Reviewed on Aug 7, 2026

East Florence Hotel Deals

Renaissance Shoals Resort & Spa

Renaissance Shoals Resort & Spa

10 Hightower Place Florence AL
Fully refundableReserve now, pay when you stay
$289 nightly
$332 total
Aug 9 - Aug 10
Total with taxes and fees
9.2/10 Wonderful! (806 reviews)
"We had a reservation for 2 queen beds but only received a king bed. We had 4 adults and it was not a comfortable stay but they did try to make it work with a trendle bed. There was a event and they were booked with no free rooms."

Reviewed on Aug 2, 2026

Renaissance Shoals Resort & Spa
Residence Inn Florence Marriott

Residence Inn Florence Marriott

1000 Sweetwater Ave Florence AL
Fully refundableReserve now, pay when you stay
$121 nightly
$139 total
Aug 30 - Aug 31
Total with taxes and fees
Residence Inn Florence Marriott
Budget Inn & Suites

Budget Inn & Suites

1238 Florence Boulevard Florence AL
$57 nightly
$64 total
Aug 11 - Aug 12
Total with taxes and fees
7.4/10 Good! (168 reviews)
"Place is awful could not stay paid and would not give a refund it stinks and there are holes in the linens dirty awful place had to book another hotel and lost everything I paid and refused a refund"

Reviewed on Aug 1, 2026

Budget Inn & Suites
See all 234 properties in East Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular East Florence attractions

River Heritage Park

9.0/10 (16 reviews)
After visiting River Heritage Park, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the area's live music.
See properties

Shoals Conference Center

6.4/10 (10 reviews)
Shoals Conference Center is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or experience the area's live music.
See properties
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.