East Prairie Vacations

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East Prairie Hotel Deals

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $125 total per night from Jul 2 to Jul 3
$125 total
Jul 2 - Jul 3
Total with taxes and fees
9.6/10 Exceptional! (1,002 reviews)
"This was a wonderful stay for the night while traveling. Thankful for the recommendation from the front desk to eat at Lamberts restaurant 3 minutes down the road. So fun!"

Reviewed on Jun 15, 2026

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Jul 12 to Jul 13
$78 total
Jul 12 - Jul 13
Total with taxes and fees
7.2/10 Good! (1,001 reviews)
"Lobby reeked like pot and cigarettes, room was not the cleanest and smelled like wet dog, water only got lukewarm, and milk for breakfast was days expired. Pics on Expedia definitely don’t look like the room we had."

Reviewed on Jun 8, 2026

Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $118 total per night from Jul 19 to Jul 20
$118 total
Jul 19 - Jul 20
Total with taxes and fees
9/10 Wonderful! (578 reviews)
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Reviewed on Jun 15, 2026

Hampton Inn Sikeston
See all 90 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best East Prairie Vacation Packages

East Prairie Essential Information

Language
English
Currency
U.S dollars
Population
3,200

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Frequently asked questions

How much does an East Prairie vacation package cost?
Offering excellent value package deals on Expedia, you'll be thrilled with how little a vacation to East Prairie costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to East Prairie?
If you'd like to snag a cheap East Prairie vacation package, consider visiting in January, February and October. You'll generally find better prices on flights and hotels during these months — ideal for a budget-friendly break.
How many days is enough for East Prairie?
The ideal duration for your East Prairie vacation depends on what you'd like to do. Usually, a handful of days to a week will give you enough time to check out all the main attractions and explore some hidden spots along the way.
How to find the best East Prairie package deals?
Landing a cheap East Prairie package deal is easy with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most wallet-friendly East Prairie package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book an East Prairie vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking hotels and flights individually. Better still, you can tailor your East Prairie trip to fit your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to East Prairie?
Enjoy amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment East Prairie getaway.
Does Expedia offer Book Now, Pay Later East Prairie vacation packages?
Secure your dream getaway to East Prairie with Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait for your next paycheck — we've teamed up with online lender Affirm to offer you financial flexibility. Our vacation packages with payment plans let you split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snag great deals before they sell out.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.