East Prairie Vacations from $510
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest East Prairie vacation packages
Price found within the past 48 hours. Click for updated prices.
Super 8 by Wyndham Metropolis
$510
per person
Oct 30 - Nov 1
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (QLA) to Paducah (PAH)
7/10 Good! (627 reviews)
The room was dirty and not maintained, stains in the bathtub and dirt on the walls. The breakfast was equally bad with stale cereal and terrible waffle batter.
Reviewed on Sep 18, 2026
Don't see what you're looking for?
See all available trips from Columbus to East Prairie
View all tripsStay near popular East Prairie attractions
Big Oak Tree State Park
8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
East Prairie Hotel Deals
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
$108 total
Sep 27 - Sep 28
Total with taxes and fees
9.6/10 Exceptional! (1,001 reviews)
"Our stay was comfortable and the room was nice. The staff was very kind and helpful. Complimentary dinner was a great surprise and very tasty. I've never stayed at a Drury Inn before and am very satisfied. I will look for availability from now on when we travel."
Reviewed on Sep 17, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$66 nightly
$76 total
Sep 22 - Sep 23
Total with taxes and fees
7.2/10 Good! (1,003 reviews)
"Staff was prompt and helpful in getting us set up in a new room. Only because the outlet for the blowdryer wasn't working. The facilities were kinda updated. There could have been additional attention paid to light switch covers being VERY outdated and furniture being worn and tattered."
Reviewed on Sep 17, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$87 nightly
$99 total
Sep 27 - Sep 28
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best East Prairie Vacation Packages
East Prairie Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Population | 3,200 |
More vacations you might like
Frequently asked questions
How much does an East Prairie vacation package cost?
Offering excellent value package deals from $510 on Expedia, you'll be thrilled with how little a vacation to East Prairie costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to East Prairie?
If you'd like to snag a cheap East Prairie vacation package, consider visiting in January, February and October. You'll generally find better prices on flights and hotels during these months — ideal for a budget-friendly break.
How many days is enough for East Prairie?
The ideal duration for your East Prairie vacation depends on what you'd like to do. Usually, a handful of days to a week will give you enough time to check out all the main attractions and explore some hidden spots along the way.
How to find the best East Prairie package deals?
Landing a cheap East Prairie package deal is easy with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most wallet-friendly East Prairie package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book an East Prairie vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking hotels and flights individually. Better still, you can tailor your East Prairie trip to fit your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to East Prairie?
Enjoy amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment East Prairie getaway.
Does Expedia offer Book Now, Pay Later East Prairie vacation packages?
Secure your dream getaway to East Prairie with Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait for your next paycheck — we've teamed up with online lender Affirm to offer you financial flexibility. Our vacation packages with payment plans let you split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snag great deals before they sell out.
Explore a world of travel with Expedia
- East Prairie Hotels
- Charleston Hotels
- Apartments in Charleston
- Hotels near Big Oak Tree State Park
- Hotels with Hot Tubs in Sikeston
- Sikeston Hotels
- Pet-Friendly Hotels in Charleston
- Miner Hotels
- Vacation Homes in Pinhook
- Motels in Anniston
- Rv Parks in Bertrand
- Matthews Hotels
- Cabin Rentals in Miner
- Motels in Charleston
- Condo Rentals in East Prairie
- Cheap Hotels in Charleston
- B&B in Charleston
- Apartments in East Prairie
- Motels in East Prairie
- Pet-Friendly Hotels in Sikeston
- Rv Parks in Mississippi County
- Wyndham Hotels in Charleston
- Hotels with Bars in Sikeston
- New Madrid Hotels
- Motels in Matthews
- Cabin Rentals in East Prairie
- Bertrand Hotels
- Rv Parks in Miner
- Cabin Rentals in Sikeston
- Cape Girardeau Hotels
- Cabin Rentals in Charleston
- Cheap Hotels in Sikeston
- Rv Parks in East Prairie
- Hotels with Restaurants in Charleston
- Motels in Miner
- 5 Star Hotels in Charleston
- Cottages in East Prairie
- Hotels with a Pool in Charleston
- Family Hotels in Charleston
- Hotels with an Indoor Pool in Sikeston
- Flights from Sikeston
- Flights from Cape Girardeau (CGI) to Sikeston (SIK)
- Flights from Bertrand
- Flights from Charleston
- Flights from Nashville (BNA) to Sikeston (SIK)
- Flights to Sikeston
- Flights from Dallas (DFW) to Sikeston (SIK)
- Flights from Minneapolis (MSP) to Sikeston (SIK)
- Flights from Houston (IAH) to Sikeston (SIK)
- Flights from Chicago (ORD) to Sikeston (SIK)
- Flights from Cape Girardeau Municipal
- Flights to Charleston
- Flights from Sikeston Memorial Municipal
- Flights to Bertrand
- Flights from East Prairie
- Flights from Memphis (MEM) to Sikeston (SIK)
- Flights from Philadelphia (PHL) to Sikeston (SIK)
- Central Park
- Delmo Park
- Marston Community Center
- Litz Park
- Hayti Vacations
- Fort D Historic Site
- Bernie Vacations
- Dexter Vacations
- Hunter Valley Winery
- Eden Spa & Salon
- Hunter-Dawson State Historic Site
- Hayti Pentecostal Holiness Church
- The Heritage House
- Hayti Park
- Marble Hill Vacations
- Visit Sikeston
- Southeast Missouri State University
- Charleston Vacations
- Stoddard County Civil War Memorial Cemetery
- Visit Charleston
- Cape Splash Family Aquatic Center
- Cape Girardeau Vacations
- Riverfront Bridge Park
- Trail of Tears State Park
- Sikeston Depot Museum
- Century Casino Caruthersville
- New Madrid Historical Museum
- Qulin Vacations
- Black Island Conservation Area
- Sikeston Vacations
- Cape Rock Park
- Bloomfield Vacations
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
