
Florida Keys Vacations from $481
Book a Hotel + Flight or Car together to unlock savings
Your Florida Keys Vacation
When adventure calls, answer it with a tailor-made vacation package to Florida Keys. Wherever it is you're going and whatever you have planned, prepare to discover a destination with plenty to offer. A trip to Florida Keys wouldn't be complete without spending some time in its best cities, starting with Key West. Two of the top attractions here include Smathers Beach and Mallory Square. Key Largo is another favorite city with Florida Keys travelers. Visitors to this destination enjoy John Pennekamp Coral Reef State Park and Jimmy Johnson's Big Chill. Expedia has hotels, flights and whatever else you need to help you put together your very own customized Florida Keys vacation today.
The Latest Florida Keys vacation packages


Cavalier Hotel South Beach
Reviewed on Nov 22, 2025

The Shelborne By Proper, a Member of Design Hotels
Reviewed on Nov 25, 2025

Casablanca Miami Beach
Reviewed on Nov 12, 2025

Where to stay in Florida Keys

Old Town Key West
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Discover the most popular places to visit in Florida Keys

Duval Street
Along one of the southernmost streets in the continental U.S., enjoy a lively area filled with shops, pubs, restaurants and lots of sidewalk acts and vendors.

Mallory Square
Arrive at this square at day’s end to find street performers, food carts and one of the most beautiful sunsets in the United States.

Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
What to do in Florida Keys

Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

Key Largo Coral Reef Glass Bottom Boat Adventure

Miami to Key West Day Trip with Activity Options
Florida Keys Hotel Deals

Chesapeake Beach Resort
Room was very clean, view was amazing, breakfast was great, and restaurants and activities nearby. Only issue was hot tub not working. Would’ve enjoyed that amenity!
Reviewed on Nov 24, 2025

Cheeca Lodge & Spa
This was a great property. Numerous dining options. I was so impressed with the grouper sandwich, possibly the best that I’ve eaten in 30 years in Florida and the Florida Keys. The customer service staff was amazing and so thorough informing guest at check-in of all of the amenities available to ...
Reviewed on Nov 23, 2025

Waterside Suites & Marina
Great place to stay!
Reviewed on Nov 16, 2025
Find the Best Florida Keys Vacation Packages
Florida Keys Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Miami Intl. Airport (MIA) |























