Name: Reefhouse Resort & Marina
Price range: $286 total
Rating: 9.2

Your Florida Keys Vacation

When adventure calls, answer it with a tailor-made vacation package to Florida Keys. Wherever it is you're going and whatever you have planned, prepare to discover a destination with plenty to offer. A trip to Florida Keys wouldn't be complete without spending some time in its best cities, starting with Key West. Two of the top attractions here include Smathers Beach and Mallory Square. Key Largo is another favorite city with Florida Keys travelers. Visitors to this destination enjoy John Pennekamp Coral Reef State Park and Jimmy Johnson's Big Chill. Expedia has hotels, flights and whatever else you need to help you put together your very own customized Florida Keys vacation today.

The Latest Florida Keys vacation packages

Price found within the past 48 hours. Click for updated prices.

The Penguin Hotel

South Beach

Save 100% on your flight

$383

per person

Oct 29 - Nov 3

found 1 day ago

Roundtrip flight included

Boston (BOS) to Miami (MIA)

8.2/10 Very Good! (1,414 reviews)

The only thing missing was breakfast. We were given drink vouchers, however we don’t drink.

Reviewed on Aug 21, 2025

The Retreat Collection at 1 Hotel & Homes South Beach

South Beach

$8,203

per person

Nov 8 - Nov 12

found 1 day ago

Roundtrip flight included

Boston (BOS) to Miami (MIA)

8/10 Very Good! (1 review)

Avalon Hotel

South Beach

Save 100% on your flight

$393

per person

Nov 16 - Nov 21

found 1 day ago

Roundtrip flight included

Boston (BOS) to Miami (MIA)

9.2/10 Wonderful! (1,018 reviews)

Cross street to the beach. Very popular and busy area. Staffs are nice.

Reviewed on Aug 25, 2025

Henrosa Hotel

South Beach

Save 100% on your flight

$493

per person

Oct 30 - Nov 6

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Miami (MIA)

8.4/10 Very Good! (814 reviews)

Good location, very walkable. Front desk staff is very nice.

Reviewed on Aug 8, 2025

President Hotel

South Beach

Save 100% on your flight

$389

per person

Oct 29 - Nov 3

found 1 day ago

Roundtrip flight included

Boston (BOS) to Miami (MIA)

8.4/10 Very Good! (1,773 reviews)

It was chill but could be better with hotel overall upkeep

Reviewed on Aug 25, 2025

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Where to stay in Florida Keys

Find the best Florida Keys areas and neighborhoods for the activities you enjoy most. Learn more about Florida Keys

Old Town Key West

3 out of top 10 points of interest in this area

4.5/5(226 area reviews)

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Audubon House and Tropical Gardens featuring a house

Key West Historic District

2 out of top 10 points of interest in this area

4.5/5(4,033 area reviews)

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Discover the most popular places to visit in Florida Keys

Duval Street

Along one of the southernmost streets in the continental U.S., enjoy a lively area filled with shops, pubs, restaurants and lots of sidewalk acts and vendors.

Southernmost Point

Snap a memorable photograph from the edge of North America at this monumental landmark.

Mallory Square

Arrive at this square at day’s end to find street performers, food carts and one of the most beautiful sunsets in the United States.

What to do in Florida Keys

12 hours Day at Key West With Boat Tour and Snorkeling

Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar

$27

per adult

78% of travellers recommend

12-Hours Day Trip in Key West from Miami

Full Day Trip in Key West from Miami

$27

per adult

Aerial view of people snorkeling in Key West

Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

$40

per adult

92% of travellers recommend

See all activities in Florida Keys

Florida Keys Hotel Deals

Chesapeake Beach Resort

83409 Overseas Hwy, Islamorada, FL

Fully refundableReserve now, pay when you stay

$150 nightly

$169 total

Sep 16 - Sep 17

Total with taxes and fees

9/10 Wonderful! (1,499 reviews)

"Fresh new rooms. Location was right on the ocean. Great breakfast, made for you. Front desk staff was amazing. Super accommodating and great communication. The only thing I would have recommended is that during construction they should have instated a bathroom vanity. Would return there again!!"

Reviewed on Aug 24, 2025

Reefhouse Resort & Marina

103800 Overseas Hwy, Key Largo, FL

Fully refundableReserve now, pay when you stay

$259 nightly

$286 total

Aug 26 - Aug 27

Total with taxes and fees

9.2/10 Wonderful! (1,300 reviews)

"Loved it"

Reviewed on Aug 22, 2025

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL

Fully refundableReserve now, pay when you stay

$205 nightly

$231 total

Sep 2 - Sep 3

Total with taxes and fees

9/10 Wonderful! (1,157 reviews)

"Excellent place for a restful weekend"

Reviewed on Aug 23, 2025

See all 8,274 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.