Grand Center Vacations from $274

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Your Grand Center Vacation

Book one of our vacation packages to Grand Center and experience the wonders of this interesting neighborhood. Especially renowned for its culture, your next awesome adventure can be found right here. Some popular nearby attractions to see during your trip to Grand Center include Busch Stadium, Gateway Arch and Dome at America’s Center. Don't just dream it — turn it into a reality! Reserve your ideal Grand Center vacation with Expedia and experience travel your way.

The Latest Grand Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Save 100% on your flight
Price was $378, price is now $274 per person
$274
per person
Feb 14 - Feb 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again.

Reviewed on Dec 22, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $590, price is now $298 per person
$298
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Breakfast great! Pool: hot tub being renovated.

Reviewed on Jan 12, 2026

White House at Grand Central

White House at Grand Central

4 out of 5
Grand Center
Save 100% on your flight
Price was $448, price is now $288 per person
$288
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (123 reviews)
Very clean and very friendly people

Reviewed on Nov 11, 2025

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport

2.5 out of 5
Woodson Terrace
Save 100% on your flight
Price was $565, price is now $412 per person
$412
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (96 reviews)
I love the breakfast and the area itself. The staff were very helpful. They take care of their guess.

Reviewed on Jan 13, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Save 100% on your flight
Price was $456, price is now $336 per person
$336
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
I always love staying Angad art hotel!

Reviewed on Jan 11, 2026

Where to stay in Grand Center

Find the best Grand Center areas and neighborhoods for the activities you enjoy most. Learn more about Grand Center
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

Grand Center Hotel Deals

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $150 total per night from Jan 19 to Jan 20
$150 total
Jan 19 - Jan 20
Total with taxes and fees
8.8/10 Excellent! (1,050 reviews)
I always love staying Angad art hotel!

Reviewed on Jan 11, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
White House at Grand Central

White House at Grand Central

4 out of 5
3805 Lindell Blvd St. Louis MO
$124 nightly
The price is $145 total per night from Jan 20 to Jan 21
$145 total
Jan 20 - Jan 21
Total with taxes and fees
8.4/10 Very Good! (126 reviews)
Great place

Reviewed on Dec 27, 2025

White House at Grand Central
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $147 total per night from Jan 16 to Jan 17
$147 total
Jan 16 - Jan 17
Total with taxes and fees
8.4/10 Very Good! (4,043 reviews)
Room was clean, excellent view!

Reviewed on Jan 13, 2026

Hyatt Regency St. Louis at The Arch
See all 1,829 properties in Grand Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Grand Center

Fox Theater showing signage

Fox Theater

Enjoy an evening of comedic, dramatic and musical entertainment at this grand theater. Delve into its history on a guided tour, including behind-the-scenes details.

Fox Theater
Pulitzer Foundation for the Arts which includes modern architecture

Pulitzer Foundation for the Arts

Immerse yourself in modern art, architecture, culture and ideas at this unusual gallery.

Pulitzer Foundation for the Arts

Sheldon Concert Hall

You can enjoy a show at Sheldon Concert Hall during your stay in St. Louis. Experience the area's great live music or attend a baseball game.

Sheldon Concert Hall

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis Premium Driving Tour with Boat Ride & Arch

St. Louis Premium Driving Tour with Boat Ride & Arch

$174
per adult
100% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.