East Main Street, CO

Grand Junction

Independence Monument in Colorado National Monument

Popular places to visit


East Main Street Hotel Deals

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.

Grand Junction CO
$278 nightly
The price is $319 total per night from Apr 28 to Apr 29
$319 total
Apr 28 - Apr 29
Total with taxes and fees
Stay at this vacation home in Grand Junction. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Museum of the West and Western Colorado ...
10/10 Exceptional! (34 reviews)
Great location walking distance to downtown.

Reviewed on Apr 19, 2026

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.
Dtwn Walkability! Grand Junction Couple's Retreat

Dtwn Walkability! Grand Junction Couple's Retreat

3 out of 5
Grand Junction CO
$229 nightly
The price is $262 total per night from Apr 27 to Apr 28
$262 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this apartment in Grand Junction. Enjoy free parking and air conditioning. Popular attractions Museum of the West and Western Colorado Botanical Gardens ...
10/10 Exceptional! (3 reviews)
Great quite spot
Quite little apartment with enough room for two. Wish the curtains were blackout as the early morning sun was super bright. Otherwise it was a great spot close to the college.

Reviewed on Jul 25, 2025

Dtwn Walkability! Grand Junction Couple's Retreat
Launch your Colorado adventures – Historic Downtown convenience

Launch your Colorado adventures – Historic Downtown convenience

Grand Junction CO
$179 nightly
The price is $205 total per night from May 17 to May 18
$205 total
May 17 - May 18
Total with taxes and fees
Stay at this vacation home in Grand Junction. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Museum of the West and Western Colorado ...
10/10 Exceptional! (98 reviews)
Very nice property. Very clean, spacious, comfortable beds and easy check in and communication. Located just blocks from Main Street with many shops, restaurants, breweries and art. Also blocks from the Riverfront Trail which is great for biking and walking. Would definitely return to this property ...

Reviewed on Mar 31, 2026

Launch your Colorado adventures – Historic Downtown convenience
Grand Lodge Pet-Friendly Home w/ Workspace

Grand Lodge Pet-Friendly Home w/ Workspace

Grand Junction CO
Book a stay at this family-friendly vacation home in Grand Junction. Enjoy free WiFi, a water park, and a garden. Popular attractions Museum of the West and ...
10/10 Exceptional! (21 reviews)
Great location, perfect for walking to downtown Grand Juntion. It was a bit warm and not all bedrooms upstairs had A/C vents. Plenty of room to spread out. Really enjoyed our stay.

Reviewed on Apr 6, 2026

Grand Lodge Pet-Friendly Home w/ Workspace
Grand Vista Hotel

Grand Vista Hotel

3.5 out of 5
2790 Crossroads Blvd Grand Junction CO
$71 nightly
The price is $81 total per night from Apr 27 to Apr 28
$81 total
Apr 27 - Apr 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,609 reviews)
Had to move room due to strange small in room (maybe from the old A/C unit in the room

Reviewed on Apr 23, 2026

Grand Vista Hotel
Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction

4 out of 5
743 Horizon Dr Grand Junction CO
$137 nightly
The price is $157 total per night from Apr 26 to Apr 27
$157 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this family-friendly hotel in Grand Junction. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
8.2/10 Very Good! (1,000 reviews)
Clean comfortable stay. Would stay again

Reviewed on Apr 23, 2026

Doubletree Hotel Grand Junction
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around East Main Street

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Lincoln Park Historic District

While Lincoln Park Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Western Colorado Botanical Gardens and Mesa County Fairgrounds.

Lincoln Park Historic District
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Washington Park

While Washington Park isn't home to many top sights, Western Colorado Botanical Gardens and Bananas Fun Park are some notable places to visit nearby.

Washington Park
Bisbee, a historical mining town in South-Eastern Arizona, America, USA. A small town founded in 1880 with amazing old buildings, architecture and a fun travel destination.

7th Street Historic District

When in 7th Street Historic District, you can plan a visit to Western Colorado Botanical Gardens and Bananas Fun Park, some noteworthy sights in the nearby area.

7th Street Historic District
Aerial View of Christmas Lights in Grand Junction, Colorado at Dusk

Downtown

While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Downtown
Sunrise at the Grand View Overlook in Colorado National Monument

Historic Grand Junction

Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Historic Grand Junction
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Grandview

While there might not be top attractions in Grandview, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Grandview


East Main Street, CO

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