East Main Street, CO
Grand Junction

Visit East Main Street
Popular places to visit

Canyon View Park
Explore the lovely green spaces of Canyon View Park and enjoy the biking trails in Grand Junction. Check out the notable monuments and lively bars in this family-friendly area.
Colorado Mesa University
Enjoy the collegiate vibe at Colorado Mesa University during your stay in Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its top-notch restaurants.
St Mary's Medical Center
Though St Mary's Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Grand Junction while you are here.
Two Rivers Convention Center
Learn about the events happening at Two Rivers Convention Center during your trip to Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its wineries.
Redlands Mesa Golf Club
Enjoy a round of golf in Grand Junction at Redlands Mesa Golf Club. Check out the notable monuments and lively bars in this family-friendly area.
Mesa County Fairgrounds
Enjoy an outing to Mesa County Fairgrounds during your stay in Grand Junction.
East Main Street Hotel Deals

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.
Great house and even a greater location! We could walk to all activities on Main St. House was very comfortable and we certainly enjoyed the hot tub after a day out visiting all the wineries, shopping, and great food! Thanks to our host, Ron, that answered all my questions!
Reviewed on Mar 3, 2026

Launch your Colorado adventures – Historic Downtown convenience
Clean, really cute, and well decorated
Reviewed on Mar 10, 2026

Early Check-in Pet Friendly Grand Lodge Groups and Families
Great location, cute property. Had everything we needed.
Reviewed on Mar 14, 2026

Grand Vista Hotel
Key card never worked so you'd have to get it redone every day. Upcharges for every little thing like parking and an expensive daily pet fee.
Reviewed on Mar 15, 2026

La Quinta Inn & Suites by Wyndham Grand Junction
Room was ok but the beds weren’t comfortable and pillows were small and uncomfortable. Pool outside was messy and have chairs thrown in empty pool
Reviewed on Mar 16, 2026

Clarion Inn Grand Junction
Needs fresh update to rooms
Reviewed on Mar 15, 2026
Check East Main Street hotel availability
Other neighborhoods around East Main Street

Lincoln Park Historic District
While Lincoln Park Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Western Colorado Botanical Gardens and Western Colorado Center for the Arts.

Washington Park
While Washington Park isn't home to many top sights, Western Colorado Center for the Arts and Western Colorado Botanical Gardens are some notable places to visit nearby.

7th Street Historic District
When in 7th Street Historic District, you can plan a visit to Western Colorado Center for the Arts and Western Colorado Botanical Gardens, some noteworthy sights in the nearby area.

Downtown
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Historic Grand Junction
Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Grandview
While there might not be top attractions in Grandview, you can explore the larger area and discover places like Western Colorado Center for the Arts and Western Colorado Botanical Gardens.
