East Main Street, CO
Grand Junction

Visit East Main Street
Popular places to visit

Canyon View Park
Explore the lovely green spaces of Canyon View Park and enjoy the biking trails in Grand Junction. Check out the notable monuments and lively bars in this family-friendly area.
Colorado Mesa University
Enjoy the collegiate vibe at Colorado Mesa University during your stay in Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its wineries.
St Mary's Medical Center
Though St Mary's Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Grand Junction while you are here.
Redlands Mesa Golf Club
Enjoy a round of golf in Grand Junction at Redlands Mesa Golf Club. Check out the notable monuments and lively bars in this family-friendly area.
Mesa County Fairgrounds
Enjoy an outing to Mesa County Fairgrounds during your stay in Grand Junction.
Two Rivers Convention Center
Learn about the events happening at Two Rivers Convention Center during your trip to Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its wineries.
East Main Street Hotel Deals

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.
Great location walking distance to downtown.
Reviewed on Apr 19, 2026

Dtwn Walkability! Grand Junction Couple's Retreat
Quite little apartment with enough room for two. Wish the curtains were blackout as the early morning sun was super bright. Otherwise it was a great spot close to the college.
Reviewed on Jul 25, 2025

Launch your Colorado adventures – Historic Downtown convenience
Very nice property. Very clean, spacious, comfortable beds and easy check in and communication. Located just blocks from Main Street with many shops, restaurants, breweries and art. Also blocks from the Riverfront Trail which is great for biking and walking. Would definitely return to this property ...
Reviewed on Mar 31, 2026

Grand Lodge Pet-Friendly Home w/ Workspace
Great location, perfect for walking to downtown Grand Juntion. It was a bit warm and not all bedrooms upstairs had A/C vents. Plenty of room to spread out. Really enjoyed our stay.
Reviewed on Apr 6, 2026

Grand Vista Hotel
Had to move room due to strange small in room (maybe from the old A/C unit in the room
Reviewed on Apr 23, 2026

Doubletree Hotel Grand Junction
Clean comfortable stay. Would stay again
Reviewed on Apr 23, 2026
Other neighborhoods around East Main Street

Lincoln Park Historic District
While Lincoln Park Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Western Colorado Botanical Gardens and Mesa County Fairgrounds.

Washington Park
While Washington Park isn't home to many top sights, Western Colorado Botanical Gardens and Bananas Fun Park are some notable places to visit nearby.

7th Street Historic District
When in 7th Street Historic District, you can plan a visit to Western Colorado Botanical Gardens and Bananas Fun Park, some noteworthy sights in the nearby area.

Downtown
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Historic Grand Junction
Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Grandview
While there might not be top attractions in Grandview, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.
