Guadalupe Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Guadalupe Hotel Deals

Residêncial Tamarindos

Residêncial Tamarindos

3 out of 5
Morro Peixe Guadalupe Lobata
$45 nightly
The price is $52 total per night from May 3 to May 4
$52 total
May 3 - May 4
Total with taxes and fees
8.6/10 Excellent! (14 reviews)
This hotel is excellent. My only issue was that someone disconnected the hot water heater and I had to check with the staff before I could get a hot shower. My room had a very good refrigerator and a comfortable bed.

Reviewed on Nov 7, 2024

Residêncial Tamarindos
Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from Apr 12 to Apr 13
$263 total
Apr 12 - Apr 13
Total with taxes and fees
Pestana São Tomé
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
$210 nightly
The price is $244 total per night from Apr 11 to Apr 12
$244 total
Apr 11 - Apr 12
Total with taxes and fees
9.4/10 Exceptional! (63 reviews)
Lovely hotel, staff and location. Very close to airport as well Recommend highly

Reviewed on Mar 8, 2026

Omali São Tomé – Principe Collection
See all 48 properties in Guadalupe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Guadalupe Vacation Packages

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How to find the best Guadalupe package deals?
Finding a cheap Guadalupe package deal is easy with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your maximum budget, apply a couple of filters and see what's available. You can fine-tune your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Guadalupe package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are usually lower.
When to book a vacation package to Guadalupe?
If you're considering a spur-of-the-moment Guadalupe trip, check out our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can find terrific deals on your flights and hotels by booking well in advance.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.