Gulf of Mexico Vacations from $362

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The Latest Gulf of Mexico vacation packages

Price found within the past 48 hours. Click for updated prices.
The Orleans Hotel & Casino
Hawks Cay Resort
The Shelborne By Proper, a Member of Design Hotels
Millennium Hilton New York One UN Plaza
The Retreat Collection at 1 Hotel & Homes South Beach
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Where to stay in Gulf of Mexico

Find the best Gulf of Mexico areas and neighborhoods for the activities you enjoy most. Learn more about Gulf of Mexico

Discover the most popular places to visit in Gulf of Mexico

What to do in Gulf of Mexico

Gulf of Mexico Hotel Deals

Hard Rock Hotel & Casino Biloxi

Hard Rock Hotel & Casino Biloxi

4 out of 5
777 Beach Blvd., Biloxi, MS
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $92 total per night from Nov 16 to Nov 17
$92 total
Nov 16 - Nov 17
Total with taxes and fees
8.2/10 Very Good! (3,506 reviews)
Staff was very accommodating and friendly. View wasn’t great but we were only in the room to sleep. They had a few restaurants and had everything we needed.

Reviewed on Nov 9, 2025

Hard Rock Hotel & Casino Biloxi
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

4 out of 5
310 Padre Blvd, South Padre Island, TX
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $93 total per night from Nov 30 to Dec 1
$93 total
Nov 30 - Dec 1
Total with taxes and fees
8.6/10 Excellent! (1,795 reviews)
It was an excellent stay The only thing I have a complaint about is that they don’t provide free breakfast

Reviewed on Nov 11, 2025

Margaritaville Beach Resort South Padre Island
Moody Gardens Hotel, Spa and Convention Center

Moody Gardens Hotel, Spa and Convention Center

4 out of 5
7 Hope Blvd, Galveston, TX
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Dec 14 to Dec 15
$102 total
Dec 14 - Dec 15
Total with taxes and fees
8.8/10 Excellent! (1,924 reviews)
It was great experience during the stay

Reviewed on Nov 4, 2025

Moody Gardens Hotel, Spa and Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Gulf of Mexico Vacation Packages

Things to do in Gulf of Mexico

The Gulf of Mexico is perfect for outdoor adventures and romantic getaways, offering stunning scenery and a variety of activities. Visitors can enjoy beach vacations, explore golf courses, and embark on family-friendly excursions. Water activities like dolphin cruises and recreational areas provide fun for everyone, while shopping centers and amusement rides add to the excitement. Whether you're looking to relax or seek adventure, the Gulf of Mexico has something for every traveler.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Best time to go to Gulf of Mexico

The best time to visit Gulf of Mexico depends on your weather preferences. The hottest average temperature around Gulf of Mexico is in July, when weather is mostly sunny and rainfall is light rain. The coolest average temperature around Gulf of Mexico is in December when weather is mostly sunny and rainfall is light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudiness
January62.6°F (17.0°C)Light RainMostly Sunny
February59.0°F (15.0°C)Light RainMostly Sunny
March64.9°F (18.3°C)Light RainMostly Sunny
April68.5°F (20.3°C)Light RainMostly Sunny
May78.6°F (25.9°C)Light RainMostly Sunny
June80.6°F (27.0°C)Light RainMostly Sunny
July83.7°F (28.700000000000003°C)Light RainMostly Sunny
August82.8°F (28.200000000000003°C)Moderate RainMostly Sunny
September82.4°F (28.0°C)Light RainMostly Sunny
October72.9°F (22.700000000000003°C)Light RainMostly Sunny
November61.3°F (16.3°C)Light RainMostly Sunny
December57.9°F (14.4°C)Light RainMostly Sunny

Tips to save on your trip to Gulf of Mexico

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Gulf of Mexico.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.