Find hotels near Highlands Regional Medical Center, Prestonsburg from $68
Check prices for these dates
Compare 129 hotels close to Highlands Regional Medical Center with room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Suites Prestonsburg West
5.2 mi from Highlands Regional Medical Center
8.6 out of 10, Excellent, (687)
$101 nightly
The price is $115
Dec 28 - Dec 29
Total with taxes and fees

Quality Inn & Suites Prestonsburg next to Mountain Arts Center
5.1 mi from Highlands Regional Medical Center
8.0 out of 10, Very Good, (356)
$105 nightly
The price is $119
Dec 7 - Dec 8
Total with taxes and fees

Ramada Hotel & Conference Center by Wyndham Paintsville
6.4 mi from Highlands Regional Medical Center
8.8 out of 10, Excellent, (543)
$108 nightly
The price is $119
Jan 1 - Jan 2, 2026
Total with taxes and fees

Super 8 by Wyndham Prestonsburg
5.2 mi from Highlands Regional Medical Center
6.4 out of 10, (515)
$62 nightly
The price is $68
Dec 21 - Dec 22
Total with taxes and fees

Days Inn by Wyndham Paintsville
6.1 mi from Highlands Regional Medical Center
7.6 out of 10, Good, (513)
$63 nightly
The price is $69
Jan 5 - Jan 6, 2026
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Highlands Regional Medical Center Hotel Reviews

Ramada Hotel & Conference Center by Wyndham Paintsville
10/10 Excellent























