The best area to stay in Huánuco is around the Plaza de Armas in the city center.
This central area is the heart of Huánuco, featuring the main square, historic buildings, and a concentration of amenities. It's easy to navigate on foot, with many shops, restaurants, and local businesses within a few blocks of the Plaza. The Huánuco Cathedral is a prominent landmark right on the square.
For solo travelers or couples, staying in this central area provides convenience and easy access to local life. You'll find a variety of dining options, from local eateries to more upscale restaurants, and it's a good base for exploring the city's main attractions, such as the Tingo Maria National Park which is easily accessible via public transport from the main square.
Travelers looking for a slightly quieter experience with convenient access to the city center might consider hotels a few blocks from the Plaza de Armas, closer to the Malecón.