
Isolotto Vacations from $937
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Your Isolotto Vacation
Reserving a tailor-made Isolotto vacation package is a good way to know the ins and outs of this unique neighborhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next vacation to Isolotto, Expedia is here to help.
The Latest Isolotto Vacation Packages

Aurum Firenze
Reviewed on Sep 2, 2026

The Moon Boutique Hotel & Spa
Reviewed on Aug 29, 2026

Aurum Uffizi
Reviewed on Sep 5, 2026

Hotel Santa Maria Novella
Reviewed on Sep 6, 2026
Where to stay in Isolotto

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo
Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.

Santa Maria Novella
Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.

San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce
One of the historic districts of Florence has a network of medieval streets lined with opulent churches, leather stores, markets and atmospheric restaurants.
Isolotto Hotel Deals

Plus Florence - Hostel

The Social Hub Florence Lavagnini
"Let me start by saying that the only big flaw with this hotel is the room design. Our first room had a sewer stench as soon as you walked in. The shower stall wasn’t sealed and the entire floor flooded after every shower unless you pointed the shower head at just the right angle. The staff very kindly ..."
Reviewed on Sep 6, 2026

The Social Hub Florence Belfiore
"This hotel was great! All new amenities, very clean and in a location ideal for access to the main train station. The pool was a highlight and, although it did get busy, we never waited long for a sun lounger. Would definitely recommend!"
Reviewed on Sep 6, 2026
Things to do

City Sightseeing Florence Hop-on Hop-off Bus Tour

Florence: Pasta Cooking Class with Unlimited Wine




















