
Isolotto Vacations from $729
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Your Isolotto Vacation
Reserving a tailor-made Isolotto vacation package is a good way to know the ins and outs of this unique neighborhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next vacation to Isolotto, Expedia is here to help.
The Latest Isolotto Vacation Packages

Aurum Firenze
Reviewed on Jan 3, 2026

Aurum Uffizi
Reviewed on Dec 15, 2025


Eurostars Florence Boutique
Reviewed on Dec 13, 2025
Where to stay in Isolotto

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Isolotto Hotel Deals

IQ Hotel Firenze
The staff was very nice willing to assist us in every request. The hotel was excellent with premium amenities. The room was amazing spacious and with a very modern decoration. The bathroom was spacious and isolated!!!! Recommend 100%
Reviewed on Dec 30, 2025

25hours Hotel Florence Piazza San Paolino
Very detailed decor and very clean!
Reviewed on Jan 5, 2026

Solo Experience Hotel
Il servizio direi ottimo, riguardo alla camera 3 cose consiglierei: 1) rivedere la canalizzazione dell'aria perchè in camera c'era un pessimo odore di aglio bruciato di cucina, evidentemente canalizzato tramite la conduttura aria, infatti anche a riscaldamento spento dalle bocchetta dell aria entrava ...
Reviewed on Jan 6, 2026
Discover the most popular places to visit in Isolotto

Piazza di Santa Maria Novella
Relax before or after a long trip in this renovated piazza just a few minutes from Florence’s main train station.

Ponte Vecchio
Take a trip over Florence’s iconic bridge, spared by the Nazis for its beauty and home to jewelers for more than four centuries.

Cathedral of Santa Maria del Fiore
The “Saint Mary of the Flower” cathedral and its towering dome have come to symbolize Florence.
Things to do

Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti























