Karlín Vacations from $749

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Your Karlín Vacation

If it's time for a riverside break, our Karlín vacation packages are just what you need. Whether you're seeking cycling, nightlife or culture, this neighborhood has something for every traveler. Your trip to Karlín wouldn't be complete without seeing leading attractions nearby such as Charles Bridge, Old Town Square and Prague Castle. Stop daydreaming and start doing. When it's time to lock in your vacation to Karlín, Expedia will help get you there.

The Latest Karlín Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Prague Castle Apartments Pawlansky

Prague Castle Apartments Pawlansky

3.5 out of 5
Prague City Center
per person
Sep 27 - Oct 2
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9/10 Wonderful! (34 reviews)
The location was amazing. So close to Charles bridge and the castle. Also access to a beautiful foreted park area within two minutes was fantastic. Views were beautiful. Considering the apartment was on the tram line it was very quiet. Having AC in both bedrooms was a blessing and the smart tv kept the kids entertained during the thunderstorm. Beds were comfortable and a washer and dryer was a huge plus. Would stay again.

Reviewed on Aug 14, 2024

The Grand Mark Prague - The Leading Hotels of the World

The Grand Mark Prague - The Leading Hotels of the World

5 out of 5
Prague City Center
Save 100% on your flight
per person
Sep 27 - Oct 2
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.4/10 Exceptional! (686 reviews)
Needed more storage space and more fruit at breakfast

Reviewed on Jun 14, 2025

BoHo Prague Hotel, Small Luxury Hotels

BoHo Prague Hotel, Small Luxury Hotels

4 out of 5
Prague City Center
Save 100% on your flight
per person
Sep 27 - Oct 2
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9.8/10 Exceptional! (1,000 reviews)
Excellent location and amazing staff that you can ask about anything.

Reviewed on Jun 28, 2025

Mandarin Oriental, Prague

Mandarin Oriental, Prague

5 out of 5
Prague City Center
Save 100% on your flight
per person
Sep 13 - Sep 16
found 18 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Prague (PRG)
9.4/10 Exceptional! (274 reviews)
A beautiful hotel in a quiet location with easy access to the historic center and to many dining and shopping options. Our room was large and comfortable. Service was friendly and helpful. Our only quibble was the breakfast buffet which was not up to the quality of the hotel or the price of the meal.

Reviewed on Jul 8, 2025

Pytloun Boutique Hotel Prague

Pytloun Boutique Hotel Prague

5 out of 5
Prague City Center
Save 100% on your flight
per person
Sep 21 - Sep 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Prague (PRG)
9/10 Wonderful! (590 reviews)
The staff was great. We stayed 5 days and had a wonderful time. Our small kids were with us. The room was one of the best we've stayed in over here in Europe. I love writing this review because they really were great. Breakfast was very good. The area has a lot of shopping a restaurants. And we Uber'd everywhere from here. Recommend this place wholeheartedly.

Reviewed on Jun 16, 2025

Where to stay in Karlín

Find the best Karlín areas and neighborhoods for the activities you enjoy most. Learn more about Karlín
Charles Bridge featuring a bridge, a city and a river or creek

Prague City Center

6 out of top 10 points of interest in this area

Discover the medieval heart of Prague, a UNESCO World Heritage Site, featuring major attractions like Prague Castle, Old Town Square, and Charles Bridge. Explore the historic district, home to the Czech Parliament, government offices, and Charles University.

Find hotels in Prague City Center

Karlín Hotel Deals

Hilton Prague
Hilton Prague
5 out of 5
Pobrezni 311/1, Prague
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $118 total per night from Jul 27 to Jul 28
$118 total
Jul 27 - Jul 28
Total includes taxes and fees
8.2/10 Very Good! (1,001 reviews)
"lovely and clean"

Reviewed on Jul 2, 2025

Hilton Prague
Botanique Hotel Prague
Botanique Hotel Prague
4 out of 5
Sokolovská 11, Prague
$67 nightly
The price is $80 total per night from Jul 20 to Jul 21
$80 total
Jul 20 - Jul 21
Total includes taxes and fees
9.2/10 Wonderful! (1,000 reviews)
Great stay!
"We had a great experience at the Hotel Botanique in Prague. The rooms were clean, the bed was very comfortable, and the service was 5-star. The room was also much larger than you typically find in reasonable priced European hotels. Overall it was a great experience and I would highly recommend it ..."

Reviewed on Jun 28, 2025

Botanique Hotel Prague
Michelangelo Grand Hotel Prague
Michelangelo Grand Hotel Prague
5 out of 5
Vladislavova 1477/20, Praha 1 - Nove Mesto, Prague
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $154 total per night from Jul 13 to Jul 14
$154 total
Jul 13 - Jul 14
Total includes taxes and fees
9.4/10 Exceptional! (2,613 reviews)
"The location was excellent and all staff were very helpful"

Reviewed on Jul 9, 2025

Michelangelo Grand Hotel Prague
See all 2,601 properties in Karlín
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Discover the most popular places to visit in Karlín

Karlin Studios

You can study the exhibits at Karlin Studios, a museum with a story of its own, during your travels to Prague. Discover the acclaimed theater scene and temples in this culturally rich area.

Karlin Studios

Kasárna Karlín

Find out about the history of Prague when you spend time at Kasárna Karlín. Check out the shops and top-notch restaurants in this family-friendly area.

Kasárna Karlín

Things to do

Big Bus Prague Hop-On Hop-Off Tour and optional River Cruise

Big Bus Prague Hop-On Hop-Off Tour and optional River Cruise

$30
per adult
84% of travellers recommend
Big Bus Prague Hop-On Hop-Off Tour and optional River Cruise
Prague Eat, Sip and Make New Friends on Food and Drink Tour

Prague Eat, Sip and Make New Friends on Food and Drink Tour

$167
per adult
100% of travellers recommend
Prague Eat, Sip and Make New Friends on Food and Drink Tour
Karlovy Vary

Karlovy Vary City of dreams. With expert English-speaking guide from Prague

$81
per adult
Karlovy Vary City of dreams. With expert English-speaking guide from Prague
See all activities in Prague
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.