If you're a fan of stage performances, make sure you catch a show at La Malhablada. Make a reservation ahead of time to secure the best seats.
You'll have sightseeing choices galore when in Salamanca Centro. La Malhablada is a good place to begin here, but there are plenty of other fine spots to explore. New Cathedral of Salamanca, San Esteban Convent, and Art Nouveau and Art Deco Museum are near the arts and culture attraction and will top off your day nicely.