Top 10 Hotels in Lilbourn, MO (from $58) 2026 - Competitive Prices

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Our top choices for Lilbourn hotels

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

A room with a brown leather sofa, a red chair, and a cityscape painting on the wall.

A modern kitchen with a built-in microwave, a black refrigerator, and a wooden countertop.

A modern kitchen with a stone backsplash, a dining area with red chairs, and a red accent wall with a framed picture.

1. Super 8 By Wyndham Marston

Marston

Brenda

$56 nightly

$64 total

Oct 21 - Oct 22

Total with taxes and fees

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

2. Hampton Inn Sikeston

Sikeston

Lori

$100 nightly

$114 total

Oct 18 - Oct 19

Total with taxes and fees

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

$93 nightly

$106 total

Oct 18 - Oct 19

Total with taxes and fees

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

4. Drury Inn & Suites Sikeston, MO

Sikeston

Tim

$94 nightly

$108 total

Oct 29 - Oct 30

Total with taxes and fees

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

5. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

$101 nightly

$115 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

6. Best Western Plus Sikeston I-55

Sikeston

Shelley

$83 nightly

$95 total

Oct 15 - Oct 16

Total with taxes and fees

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

7. TownePlace Suites by Marriott Sikeston

Sikeston

Rubin

$109 nightly

$124 total

Oct 22 - Oct 23

Total with taxes and fees

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

$58 nightly

$66 total

Oct 25 - Oct 26

Total with taxes and fees

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

9. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

$66 nightly

$76 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A motel with a covered entrance, multiple rooms, and a parking lot.

10. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Laura

$57 nightly

$65 total

Oct 21 - Oct 22

Total with taxes and fees

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A living room with two sofas, a coffee table, a TV, and a cabinet.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

11. Comfort Inn & Suites Sikeston I-55

Sikeston

Kathryn

$79 nightly

$90 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel room with two beds, a television, a desk, and a mirror.

A motel with a covered outdoor seating area and a parking lot.

A hotel room with a bed, a desk, a television, and a seating area with a small table.

A Travel Inn with a sign indicating affordable rooms, a parking lot, and a clear sky.

12. Travel Inn Marston I-55 by Hotel O

Marston

Frank

$53 nightly

$60 total

Oct 22 - Oct 23

Total with taxes and fees

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

13. Hampton Inn By Hilton Dexter

Dexter

Bryan

$98 nightly

$111 total

Oct 25 - Oct 26

Total with taxes and fees

A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.

Two grey armchairs with green cushions, a small side table with a white lamp, and wall-mounted sconces.

A hotel room with a brick wall, two beds, a desk with a TV, and a patterned carpet.

A gym with treadmills, elliptical machines, and a mirrored wall.

14. Drury Inn & Suites Hayti Caruthersville

Hayti

Cynthia

$98 nightly

$112 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a counter, a coffee machine, and seating.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

15. Country Yard Inn and Suite

Sikeston

William

$54 nightly

$61 total

Oct 20 - Oct 21

Total with taxes and fees

A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

A building with multiple floors and a flat roof, surrounded by a grassy area with trees.

A parking lot with a grassy area and trees in the background.

A bathroom with a bathtub, a toilet, and a sink.

16. Reelfoot Lake Inn

Tiptonville

Danny

$54 nightly

$62 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel breakfast area with a buffet setup, including a refrigerator, coffee machine, and various food items.

A lobby with a reception desk, seating area, and a television mounted on the wall.

A lobby with a reception desk, a flat-screen TV, seating area with chairs and ottomans, and potted plants.

A hotel room with two beds, a window with curtains, a chair, and bedside tables with lamps.

17. Quality Inn Hayti North

Hayti

Winston

$59 nightly

$67 total

Nov 1 - Nov 2

Total with taxes and fees

A diner with booth seating, a checkered floor, and a counter with a cash register.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

18. Travelodge by Wyndham Dexter

Dexter

Steven

$86 nightly

$97 total

Nov 1 - Nov 2

Total with taxes and fees

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

19. Dexter Inn

Dexter

Edward

$68 nightly

$76 total

Oct 22 - Oct 23

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

20. Econo Lodge Dexter

Dexter

Herman

$51 nightly

$58 total

Nov 13 - Nov 14

Total with taxes and fees

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Top Lilbourn Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent

"Seamless check-in and check-out. Reserved the room through Expedia only moments before stopping for the night. Everything in the room seemed cleaned and sanitized. The breakfast on Sunday morning was quite delicious before we got back on the road to home."

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"good, clean, affordable :)"

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Everything perfect. Drury Inns sweat the details."

Reelfoot Lake Inn

8/10 Good

"Dated but descent."

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"Easy parking, our bathroom sink was leaning forward and we had to place our soap in the sink so it didn't slide on the floor."

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"Clean, comfortable room. Nice staff and good breakfast choices."

Hampton Inn By Hilton Dexter

10/10 Excellent

"This place is Brand new and really great!"

The Dragonfly - Sleeps up to 8, Lake views.

10/10 Excellent

"This was the perfect place for us to stay when we were in town for the real foot art and craft show the house was clean. Nice size. We loved the views we had. A a fire that we sat around with and did some mores. It was just wonderful Kristi the host was awesome, very responsive and helpful. Hope to stay there again in the future!"

Super 8 By Wyndham Marston

8/10 Good

"Very clean and a very friendly staff! Air conditioner in room wasn’t working perfectly so it felt very humid but overall was not bad. I would stay here again!"

More cheap stays in Lilbourn

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

$57 nightly

$65 total

Oct 21 - Oct 22

Total with taxes and fees

7/10 Good! (687 reviews)

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

$66 nightly

$76 total

Nov 1 - Nov 2

Total with taxes and fees

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

$83 nightly

$95 total

Oct 15 - Oct 16

Total with taxes and fees

8.4/10 Very Good! (1,000 reviews)

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

$93 nightly

$106 total

Oct 18 - Oct 19

Total with taxes and fees

8.8/10 Excellent! (517 reviews)

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

$100 nightly

$114 total

Oct 18 - Oct 19

Total with taxes and fees

New Orleans Inn Portageville

600 US-61 Portageville MO

Get rates

8/10 Very Good! (798 reviews)

Hotels in Lilbourn with star-rating

Frequently asked questions

What is the best area to stay in Lilbourn?

The best area to stay in Lilbourn is near the intersection of US-61 and US-62, as this is where you'll find the most amenities and convenient access to the surrounding region.This central area of Lilbourn is primarily characterized by its easy access to major roadways, making it ideal for travelers passing through or using Lilbourn as a base for exploring southeastern Missouri. While it's a smaller town, this intersection offers the most concentration of services, including dining options and local businesses.For travelers seeking convenience, especially those on a road trip, this area is a practical choice. The proximity to US-61 and US-62 means less time navigating local streets and more time on your journey or at your destination.

When is the best time to go to Lilbourn?

The best time to go to Lilbourn is during the spring (April to May) and fall (September to October) months.These seasons offer pleasant weather, with moderate temperatures and lower humidity, making it comfortable for outdoor activities and exploring the local area. Spring brings blooming dogwood trees and azaleas, while fall showcases colorful foliage, providing a scenic backdrop for your visit.Families often find these times ideal for visiting, as the mild weather is superb for enjoying local parks or taking day trips to nearby natural attractions without the extreme heat of summer or the chill of winter.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lilbourn.

How much is the nightly rate at a Lilbourn hotel?

Prices for hotels in Lilbourn often vary, but you can find a great deal from $58 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Find hotels in Lilbourn, MO from $58

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Lilbourn

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lilbourn hotels

1. Super 8 By Wyndham Marston

2. Hampton Inn Sikeston

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

4. Drury Inn & Suites Sikeston, MO

5. Fairfield Inn & Suites by Marriott Sikeston

6. Best Western Plus Sikeston I-55

7. TownePlace Suites by Marriott Sikeston

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

9. Days Inn and Suites by Wyndham Sikeston

10. Super 8 by Wyndham Sikeston/Miner Area

11. Comfort Inn & Suites Sikeston I-55

12. Travel Inn Marston I-55 by Hotel O

13. Hampton Inn By Hilton Dexter

14. Drury Inn & Suites Hayti Caruthersville

15. Country Yard Inn and Suite

16. Reelfoot Lake Inn

17. Quality Inn Hayti North

18. Travelodge by Wyndham Dexter

19. Dexter Inn

20. Econo Lodge Dexter

Top Lilbourn Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

Super 8 by Wyndham Sikeston/Miner Area

Drury Inn & Suites Sikeston, MO

Reelfoot Lake Inn

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn By Hilton Dexter

The Dragonfly - Sleeps up to 8, Lake views.

Super 8 By Wyndham Marston

More cheap stays in Lilbourn

Super 8 by Wyndham Sikeston/Miner Area

Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn Sikeston

New Orleans Inn Portageville

Hotels in Lilbourn with star-rating

Frequently asked questions

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