Come to Sikeston and enjoy its food, riverfront, and university life.

Discover the family-friendly area of Sikeston—restaurants, a scenic riverfront, and top sights from Isle Casino Cape Girardeau to Shawnee National Forest.

Known for

Dining, Family-Friendly and Shopping

Top Hotels in Sikeston

Estimated price for 1 night / 2 adults
Image for Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
$65/night
Aug 25 - Aug 26
4.2/5Very Good! (785 reviews)

Located in the heart of Cape Girardeau, this hotel is 2.4 mi (3.9 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Isle Casino Cape Girardeau ...

4.2/5Very Good! (785 reviews)

"I have stayed in other hotels in Cape,Pear Tree medical was much better. It was clean, modern, with comfortable beds and pillows. They are pet friendly, the outdoor pool was a nice addition. The breakfast was mostly carbs with no protein but for the price was pleased. Very centrally located and close ..."…"

Reviewed on Aug 20, 2019

Pear Tree Inn Cape Girardeau Near the Medical Center
Image for Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
$79/night
Aug 24 - Aug 25
4.4/5Wonderful! (712 reviews)

Situated in Cape Girardeau, this hotel is 2.5 mi (4 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Isle Casino Cape Girardeau and Shawnee ...

4.4/5Wonderful! (712 reviews)

"The night clerk who checked us in was a little short on words but other than that it was good. The unique inner rooms with the large center were nice for socializing after hours."…"

Reviewed on Aug 19, 2019

Auburn Place Hotel And Suites
Image for Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
$105/night
Aug 25 - Aug 26
4.8/5Exceptional! (338 reviews)

Situated in Cape Girardeau, this hotel is 2.3 mi (3.7 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Isle Casino Cape Girardeau and Shawnee ...

4.8/5Exceptional! (338 reviews)

"Safe and clean, attentive staff ready to help. Would recommend."…"

Reviewed on Jul 20, 2019

Drury Plaza Hotel Cape Girardeau Conference Center

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