Sikeston, MO

Travel Guide

Photo by Ryan Coleman
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
$95 nightly
The price is $108 total per night from Dec 21 to Dec 22
$108 total
Dec 21 - Dec 22
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (442 reviews)
Yes

Reviewed on Dec 10, 2025

Hampton Inn Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
$90 nightly
The price is $103 total per night from Dec 18 to Dec 19
$103 total
Dec 18 - Dec 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,003 reviews)
Clean room and spacious

Reviewed on Dec 8, 2025

Drury Inn & Suites Sikeston, MO
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
$71 nightly
The price is $81 total per night from Dec 21 to Dec 22
$81 total
Dec 21 - Dec 22
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
Easy parking , quiet and comfortable bed , we’ll stop again on our way back

Reviewed on Dec 7, 2025

Best Western Plus Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Brand new cabin in the woods with hot tub  1/2 mile from Starview Winery

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery

Cobden IL
Stay at this cabin in Anna. Enjoy patios, an in-room coffeemaker, and in-room fireplaces. Popular attractions StarView Vineyards and King Neptune Memorial are ...
9.8/10 Exceptional! (150 reviews)
Perfect little getaway! Thanks!!

Reviewed on Oct 29, 2025

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna IL
Stay at this cabin in Anna. Enjoy a garden, patios, and cable/satellite TV service. Our guests praise the helpful staff and the property condition in our reviews. ...
9.8/10 Exceptional! (403 reviews)
Very clean, courteus staff. Beautiful area and quiet. Very relaxing.

Reviewed on Nov 4, 2025

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Beautiful location in the secluded woods

Beautiful location in the secluded woods

Pomona IL
Stay at this vacation home in Pomona. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Pomona Winery and Von Jakob Winery & Brewery are located ...
9.8/10 Exceptional! (60 reviews)
Great host. Secluded location. Very nice house that was spotless.

Reviewed on Nov 24, 2025

Beautiful location in the secluded woods
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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