Title: Visit Lilbourn: 2026 Travel Guide for Lilbourn, Missouri | Expedia.com [Hotels in Lilbourn](https://expedia.com/Lilbourn-Hotels.d553248634983590625.Travel-Guide-Hotels)[Vacation Rentals in Lilbourn](https://expedia.com/Lilbourn-Vacation-Rentals.d553248634983590625.Travel-Guide-VacationRentals)[Car Rentals in Lilbourn](https://expedia.com/Car-Rentals-In-Lilbourn.d553248634983590625.Car-Rental-Guide)[Lilbourn Vacation Packages](https://expedia.com/Lilbourn.d553248634983590625.Destination-Travel-Guides) # Lilbourn, MO ## Travel Guide ## Visit Lilbourn - Lilbourn Hotel Deals - Vacation Rentals in Lilbourn ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner Sikeston MO $94 nightly $108 total Mar 29 - Mar 30 Total with taxes and fees Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ... 9.4/10 Exceptional! (1,004 reviews) Pool not too cold and it was even snowing at one point. Staff was very friendly and helpful. Never had to wait for elevator. Breakfast waffles were excellent. Room was spacious. I’ve stayed in a lot of hotels, and this is one of the best. They get a 100/10 for amenities! Reviewed on Mar 18, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=24210&PinnedHotelID=24210&HadPinnedHotel=true®ionId=553248634983590625) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO Fully refundableReserve now, pay when you stay $97 nightly $110 total Apr 12 - Apr 13 Total with taxes and fees Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ... 9/10 Wonderful! (510 reviews) Convenient to everything we needed Reviewed on Mar 22, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=25178175&PinnedHotelID=25178175&HadPinnedHotel=true®ionId=553248634983590625) ![Drury Inn & Suites Hayti Caruthersville](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/ff3e4031_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Hayti Caruthersville 1317 E Highway 84 Hayti MO $94 nightly $107 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this business-friendly hotel in Hayti. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ... 9.4/10 Exceptional! (1,001 reviews) Hotel was clean, comfortable, and a great stay off interstate! Staff was friendly Reviewed on Mar 20, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=42109&PinnedHotelID=42109&HadPinnedHotel=true®ionId=553248634983590625) [See all 77 properties in Lilbourn](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=553248634983590625) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Duck Hunting, Fishing or Relaxing Family Vacation](https://images.trvl-media.com/lodging/37000000/36090000/36089000/36088974/d93cc56b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Duck Hunting, Fishing or Relaxing Family Vacation Hornbeak TN Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ... 10/10 Exceptional! (226 reviews) The best stocked house we’ve ever stayed at while fishing Reelfoot!!! Highly recommend and will certainly book again!!! Reviewed on Mar 20, 2026 [](https://expedia.com/Hornbeak-Hotels-Duck-Hunting.h36088974.Hotel-Information) ![Come and relax at the Refuge at beautiful Reelfoot Lake!](https://images.trvl-media.com/lodging/84000000/83580000/83572000/83571978/0a58d14b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Come and relax at the Refuge at beautiful Reelfoot Lake! Hornbeak TN Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located nearby. 9.4/10 Exceptional! (26 reviews) Everything was great Reviewed on Feb 15, 2026 [](https://expedia.com/Hornbeak-Hotels-Enjoy-Beautiful-Sunsets-At-The-HUT-2-At-Beautiful-Reelfoot-Lake.h83571978.Hotel-Information) ![Beautiful Reelfoot Lake](https://images.trvl-media.com/lodging/76000000/75270000/75267600/75267595/4d50be35_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Beautiful Reelfoot Lake Tiptonville TN Stay at this vacation home in Tiptonville. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Campbell's Point and Reelfoot Lake State Park ... 10/10 Exceptional! (97 reviews) There were 6 of us staying in this re-modeled home for the weekend. We had plenty of room. The beds were comfortable. Kitchen is well equipped. Our favorite hang out place was the back porch with a beautiful view of the lake. Our host was very responsive. We would highly recommend this home. Reviewed on Mar 19, 2026 [](https://expedia.com/Tiptonville-Hotels-Beautiful-Reelfoot-Lake.h75267595.Hotel-Information) [See all properties in Lilbourn](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634983590625&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Lilbourn hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=2026-03-22&endDate=2026-03-23)[Mar 22 - Mar 23](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=2026-03-22&endDate=2026-03-23) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=2026-03-23&endDate=2026-03-24)[Mar 23 - Mar 24](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=2026-03-23&endDate=2026-03-24) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983590625&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) ## Cities near Lilbourn ![Mississippi River Walk at New Madrid. A magnificent view of the Mississippi river from atop of the levee. A steamboat is docked down river. . ](https://images.trvl-media.com/place/3000445315/970b11d9-266d-426a-9577-5e745e0939b7.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### New Madrid - Cities near Lilbourn - Places of interest [Marston](https://expedia.com/Marston.dx55824)[Portageville](https://expedia.com/Portageville.dx183487)[Catron](https://expedia.com/Catron.dx3000349317)[Gideon](https://expedia.com/Gideon.dx3000349377)[Risco](https://expedia.com/Risco.dx3000349516)[New Madrid](https://expedia.com/New-Madrid.dx3000445315) - [Mississippi River ](https://expedia.com/Mississippi-River-United-States-of-America.d6209928.Vacation-Attraction) - [Reelfoot Lake ](https://expedia.com/Reelfoot-Lake-Tennessee.d553248635976195913.Vacation-Attraction) - [Reelfoot Lake State Park ](https://expedia.com/Reelfoot-Lake-State-Park-Tiptonville.d553248621532655205.Vacation-Attraction) - [Central Park ](https://expedia.com/Central-Park-Sikeston.d6305608.Vacation-Attraction) - [Black Island Conservation Area ](https://expedia.com/Black-Island-Conservation-Area-Hayti.d553248621560505648.Vacation-Attraction) - [Sikeston Depot Museum ](https://expedia.com/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction) - [Hayti Park ](https://expedia.com/Hayti-Park-Hayti.d6245776.Vacation-Attraction) - [Marston Community Center ](https://expedia.com/Marston-Community-Center-Marston.d553248622945532712.Vacation-Attraction) - [Campbell's Point ](https://expedia.com/Campbells-Point-Tiptonville.d553248623744257771.Vacation-Attraction) - [The Heritage House ](https://expedia.com/The-Heritage-House-Dexter.d553248621592342444.Vacation-Attraction) - [New Madrid Historical Museum ](https://expedia.com/New-Madrid-Historical-Museum-New-Madrid.d553248621532655748.Vacation-Attraction) - [Dexter Welcome Center Depot and Museum ](https://expedia.com/Dexter-Welcome-Center-Depot-And-Museum-Dexter.d553248621592342445.Vacation-Attraction) - [Stoddard County Civil War Memorial Cemetery ](https://expedia.com/Stoddard-County-Civil-War-Memorial-Cemetery-Dexter.d553248621532655747.Vacation-Attraction) - [Hunter-Dawson State Historic Site ](https://expedia.com/Hunter-Dawson-State-Historic-Site-New-Madrid.d553248621532655794.Vacation-Attraction) - [Hayti Pentecostal Holiness Church ](https://expedia.com/Hayti-Pentecostal-Holiness-Church-Hayti.d6245797.Vacation-Attraction)