Sikeston Vacation Rentals

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Our top choices for Sikeston vacation rentals

Vacation Home in Cape Girardeau

Little Blue Cottage on Spanish
8.6 out of 10, Excellent, (48 reviews)
"Cozy and perfect for a couple. Great communication with the host"
United States
Beth G.
$101 nightly
The price is $101
Jan 25 - Jan 26
Total with taxes and fees
Little Blue Cottage on Spanish
9.6 out of 10, Exceptional, (47 reviews)
"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"
United States
Jordan S.
$132 nightly
The price is $138
Jan 21 - Jan 22
Total with taxes and fees
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
7.8 out of 10, Good, (30 reviews)
"A weekin Dexter at this old, charming house. "
United States
Susan R.
$189 nightly
The price is $193
Jan 26 - Jan 27
Total with taxes and fees
Dexter Homestead. Very Cozy & NEW Remodel !
8.6 out of 10, Excellent, (37 reviews)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
$211 nightly
The price is $219
Jan 21 - Jan 22
Total with taxes and fees
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Mobile Home in Jackson

The Cottage, Rusted Route Farms
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
$199 nightly
The price is $199
Jan 21 - Jan 22
Total with taxes and fees
The Cottage, Rusted Route Farms

Vacation Home in Cape Girardeau

Cozy upstairs unit in Cape Girardeau
$128 nightly
The price is $128
Jan 31 - Feb 1
Total with taxes and fees
Cozy upstairs unit in Cape Girardeau
10.0 out of 10, Exceptional, (33 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
$171 nightly
The price is $184
Jan 21 - Jan 22
Total with taxes and fees
Relax in the country at Countryside Villas! - Villa A
10.0 out of 10, Exceptional, (150 reviews)
"Such a great place and location"
United States
Tracy H.
$228 nightly
The price is $244
Jan 21 - Jan 22
Total with taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (3 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
$313 nightly
The price is $313
Jan 21 - Jan 22
Total with taxes and fees
Gorgeous 1856 Log Cabin, Completely Renovated

Cabin in Cape Girardeau

The Twisted Sassafras Treehouse
10.0 out of 10, Exceptional, (30 reviews)
"The place was awesome very clean the host was very accommodating. Nice a quiet for a relaxing stay highly recommend "
United States
Gary C.
$302 nightly
The price is $315
Jan 21 - Jan 22
Total with taxes and fees
The Twisted Sassafras Treehouse
10.0 out of 10, Exceptional, (18 reviews)
"We had a great time at Blair and her family's property. The cabin was very comfortable and as advertised. I would be happy to recommend it to others "
United States
Tammy M.
$292 nightly
The price is $292
Jan 22 - Jan 23
Total with taxes and fees
Charming Secluded Getaway Cabin within minutes of amenities
9.6 out of 10, Exceptional, (8 reviews)
"Nice place, great times"
United States
Jace W.
$419 nightly
The price is $435
Jan 21 - Jan 22
Total with taxes and fees
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
$567 nightly
The price is $607
Jan 21 - Jan 22
Total with taxes and fees
Building at Cape Girardeau Regional Airport
9.8 out of 10, Exceptional, (60 reviews)
"The property was extremely clean and well cared for.would definitely stay again. "
United States
Dan H.
$164 nightly
The price is $181
Jan 21 - Jan 22
Total with taxes and fees
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
9.8 out of 10, Exceptional, (35 reviews)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
$133 nightly
The price is $140
Jan 25 - Jan 26
Total with taxes and fees
Cozy cabins on beautiful Horseshoe Lake
10.0 out of 10, Exceptional, (405 reviews)
"Beautiful cabin with a great view of the water from the back porch! Very peaceful and relaxing stay!"
United States
Sarah F.
$187 nightly
The price is $198
Jan 22 - Jan 23
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
10.0 out of 10, Exceptional, (62 reviews)
"It was very nice and clean. We really enjoyed staying there. We would love to rent this place again. "
United States
susan B.
$158 nightly
The price is $168
Jan 27 - Jan 28
Total with taxes and fees
Beautiful location in the secluded woods
7.6 out of 10, Good, (5 reviews)
"Host was not properly notified of the booking, but made the accommodations made several trips to make sure we were checked in and comfortable. Also gave very good advice for local points of interest."
United States
Chrystine H.
$127 nightly
The price is $133
Jan 23 - Jan 24
Total with taxes and fees
Charming 2-bedroom apartment in fabulous Marble Hill with AC
9.6 out of 10, Exceptional, (41 reviews)
"Everything was very nice. We enjoyed our stay! The cabin had everything we needed."
United States
Cheri U.
$192 nightly
The price is $212
Jan 21 - Jan 22
Total with taxes and fees
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Cabin in Olive Branch

The Rested Duck Mallard Room
9.4 out of 10, Exceptional, (26 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
$133 nightly
The price is $140
Jan 26 - Jan 27
Total with taxes and fees
The Rested Duck Mallard Room
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Find out more about Sikeston

Everything you need to know about Sikeston vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Sikeston vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Sikeston vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Sikeston vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Sikeston. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Sikeston in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $101 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Sikeston rentals

At Expedia, we put the best Sikeston vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Sikeston rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Sikeston vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Sikeston. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Sikeston?

Yes, there are vacation rentals close to the most popular local attractions in Sikeston, or you can choose a more remote option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in Sikeston. Make sure you allow time to enjoy the riverfront during your vacation.

What's the top vacation rental in Sikeston?

Beautiful location in the secluded woods : Visitors like this Sikeston vacation home rental. It offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

What’s there to see and do in Sikeston?

Cultural attractions include Sikeston Depot Museum, whereas Central Park is a spot to enjoy nature. In the larger area, you’ll find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery.

What’s a vacation rental in Sikeston like?

A vacation rental is a private property you can book for a couple of days or more in Sikeston. Vacation rentals feature extras such as kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a small group gathering.