Photo by Ryan Coleman

Sikeston Vacation Rentals

    price find illustration

    Upfront pricing

    Our total price for your stay includes taxes and fees
    deals illustration

    Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jul 15 - Jul 16
Tomorrow
Jul 16 - Jul 17
This weekend
Jul 18 - Jul 20
Next weekend
Jul 25 - Jul 27

Vacation Rentals in Sikeston

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Enjoy a tranquil retreat with a pool and lush surroundings.

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.8 out of 10, Excellent, (31)
"all was so nice and we enjoyed our stay. grandkids and us loved having pool table and card games and all the peace and quiet there. thank u again for contacting me and giving us address. we appreciated that very much. "
$262 nightly
The price is $272
Jul 16 - Jul 17
Total includes taxes and fees
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Enjoy an outdoor space with a well-maintained lawn and a circular swimming pool.

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

9.0 out of 10, Wonderful, (4)
"Great property would recommend 100%. We did not have to leave the house it had everything we needed for nine adult women to have a great streetlight"
$474 nightly
The price is $492
Jul 27 - Jul 28
Total includes taxes and fees
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Charming Home Retreat Among Majestic Trees - Near SEMO, Capaha Park & Downtown
Microwave, oven, stovetop, dishwasher

Charming Home Retreat Among Majestic Trees - Near SEMO, Capaha Park & Downtown

$180 nightly
The price is $187
Jul 20 - Jul 21
Total includes taxes and fees
Charming Home Retreat Among Majestic Trees - Near SEMO, Capaha Park & Downtown
Serenity South -- Gardens, River-Views, and Refreshing Space
Enjoy cooking in this well-equipped kitchen with a refrigerator, microwave, and coffee maker.

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (135)
"The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area."
$229 nightly
The price is $245
Jul 16 - Jul 17
Total includes taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space
Little Blue Cottage on Spanish
Kitchen area with sink, cabinets, and countertop.

Little Blue Cottage on Spanish

8.6 out of 10, Excellent, (42)
"Has everything you need. Comfy and in a great location. "
$101 nightly
The price is $101
Jul 21 - Jul 22
Total includes taxes and fees
Little Blue Cottage on Spanish
Building at Cape Girardeau Regional Airport
Enjoy meals with family and friends at the dining table, surrounded by a Christmas tree and comfortable seating.

Building at Cape Girardeau Regional Airport

$571 nightly
The price is $611
Jul 16 - Jul 17
Total includes taxes and fees
Building at Cape Girardeau Regional Airport
Eagles Crossing is a Newly Renovated 3-Bed Farmhouse with a Large Deck & Hot Tub
Enjoy cooking in this well-equipped kitchen with a refrigerator, oven, and sink.

Eagles Crossing is a Newly Renovated 3-Bed Farmhouse with a Large Deck & Hot Tub

10.0 out of 10, Exceptional, (4)
"The house was beautiful, clean, and well stocked. Beautiful view and very peaceful!"
$337 nightly
The price is $349
Jul 17 - Jul 18
Total includes taxes and fees
Eagles Crossing is a Newly Renovated 3-Bed Farmhouse with a Large Deck & Hot Tub
Beautiful Cabin Retreat
Interior

Beautiful Cabin Retreat

8.2 out of 10, Very Good, (41)
"This is a very nice, peaceful cabin. The host was very friendly and accommodating. I would definitely stay here again."
$194 nightly
The price is $194
Jul 16 - Jul 17
Total includes taxes and fees
Beautiful Cabin Retreat
Magical Victorian near hiking / wine trail
Exterior

Magical Victorian near hiking / wine trail

$255 nightly
The price is $283
Jul 29 - Jul 30
Total includes taxes and fees
Magical Victorian near hiking / wine trail
Farm Immersion Experience at Rendleman Orchards
Exterior

Farm Immersion Experience at Rendleman Orchards

9.0 out of 10, Wonderful, (2)
"The setting of this well appointed cottage is just lovely. The cottage is fully equipped with anything you might need, plus there are all kinds of fun extras like classic albums and stereo, an outside grill and seating area, and a pond you can gaze at from a private porch swing. We loved being nestled among the peach trees and visiting the chicken coop in the morning. The beds are very comfortable and the “convenient store” is a great feature. We look forward to staying here again since our...
$277 nightly
The price is $303
Jul 17 - Jul 18
Total includes taxes and fees
Farm Immersion Experience at Rendleman Orchards
Beautiful location in the secluded woods
Relax on the covered porch with a table and four chairs, surrounded by lush greenery.

Beautiful location in the secluded woods

10.0 out of 10, Exceptional, (36)
"If you're looking to visit Holy Boulders, this spot gets you within 5-10 minutes of either trailhead. It was clean, roomy, and has everything you need when you're not at the crag."
$170 nightly
The price is $170
Jul 16 - Jul 17
Total includes taxes and fees
Beautiful location in the secluded woods
Gorgeous, downtown house!
Stunning hallway with a door leading to another room, featuring a chandelier and a patterned rug.

Gorgeous, downtown house!

10.0 out of 10, Exceptional, (1)
"Our stay was excellent and our host Carisa was a Great person to work with. The house was beautiful. The house worked out great for us. We had 6 people staying and we all had very comfortable beds and our own bathrooms. Great for a large family. "
$754 nightly
The price is $858
Jul 16 - Jul 17
Total includes taxes and fees
Gorgeous, downtown house!
Shop House located 8 miles from Otter Slough Conservation Area
Relax in this stylish space with a dining table, sofa, and leather couch, surrounded by mounted animal heads and a flat-screen TV.

Shop House located 8 miles from Otter Slough Conservation Area

10.0 out of 10, Exceptional, (1)
"Great place to stay! Was very nice and private while still being just minutes from anything in town."
$366 nightly
The price is $388
Jul 16 - Jul 17
Total includes taxes and fees
Shop House located 8 miles from Otter Slough Conservation Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

Can I find a vacation rental in Sikeston?

Yes, there are vacation rentals close to the most popular local attractions in Sikeston, or you can choose a more remote option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in Sikeston. Make sure you allow time to enjoy the riverfront during your vacation.

What's the top vacation rental in Sikeston?

Beautiful location in the secluded woods : Visitors like this Sikeston vacation home rental. It offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

How many vacation rentals will I find in Sikeston?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Sikeston stay.

What’s there to see and do in Sikeston?

Cultural attractions include Sikeston Depot Museum, whereas Central Park is a spot to enjoy nature. In the larger area, you’ll find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery.

What’s a vacation rental in Sikeston like?

A vacation rental is a private property you can book for a couple of days or more in Sikeston. Vacation rentals feature extras such as kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a small group gathering.