New Madrid, MO

Travel Guide

A cannon on a brick platform by a river, with a steamboat in the background.
A river with a dam, surrounded by greenery and a clear sky.
A tree-lined landscape with a river and fields.
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

New Madrid MO
$326 nightly
The price is $354 total per night from Nov 5 to Nov 6
$354 total
Nov 5 - Nov 6
Total with taxes and fees
Stay at this vacation home in New Madrid. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions New Madrid Historical Museum and River Ridge ...
10/10 Exceptional! (1 review)
"The host was very quick to respond and so great to work with for on our stay."

Reviewed on Nov 11, 2025

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
$96 nightly
The price is $109 total per night from Nov 22 to Nov 23
$109 total
Nov 22 - Nov 23
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
Hampton Inn Sikeston
Reelfoot Lake Inn

Reelfoot Lake Inn

2 out of 5
1520 State Route 21 East Tiptonville TN
$63 nightly
The price is $72 total per night from Dec 2 to Dec 3
$72 total
Dec 2 - Dec 3
Total with taxes and fees
Stay at this motel in Tiptonville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
Reelfoot Lake Inn
See all 57 properties in New Madrid
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

New Madrid MO
Stay at this vacation home in New Madrid. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions New Madrid Historical Museum and River Ridge ...
10/10 Exceptional! (1 review)
"The host was very quick to respond and so great to work with for on our stay."

Reviewed on Nov 11, 2025

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Hornbeak TN
Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (37 reviews)
"The place was nice, however the air-conditioning was out and the refrigerator did not work. It's early September in the south, no a/c means a miserable experience. After some time and several calls/messages I was able to reach the host. He said there was nothing he could do about it other than a ..."

Reviewed on Sep 7, 2026

Come and relax at the Refuge at beautiful Reelfoot Lake!
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (16 reviews)
"Great property! Highly recommend! We travel all the time and loved this place! Host was wonderful very helpful and communicative! Thanks for the wonderful experience!"

Reviewed on Nov 3, 2026

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
See all properties in New Madrid
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular New Madrid attractions

New Madrid Historical Museum

8.2/10 (36 reviews)
You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.
See properties

Frequently asked questions

Is New Madrid worth visiting?
New Madrid is worth visiting for its fascinating history, with attractions such as the New Madrid Historical Museum and the Hunter-Dawson State Historic Site. Travelers can also easily find local grocers for self-catering.
When is the best time to visit New Madrid?
The best time to visit New Madrid is from April through June, when the climate is most pleasant for exploring. For fewer crowds and better value, the quieter months of November through February are a good option, offering cooler weather for a different experience.
What is New Madrid known for?
New Madrid is known for being named after Madrid, and travelers can delve into its past at the New Madrid Historical Museum and the Hunter-Dawson State Historic Site. This riverside city, located on the Mississippi River, also offers the River Ridge Winery for visitors to enjoy.
What is a good itinerary length for New Madrid?
A good itinerary length for New Madrid is one to two days to explore key sites like the New Madrid Historical Museum and the Hunter-Dawson State Historic Site. For a more relaxed trip, two to three days allows travelers to also visit the River Ridge Winery and enjoy the local area at a leisurely pace.
What are the top things to do in and around New Madrid?
Explore New Madrid's history, natural beauty, and local flavors:


How do I plan a trip to New Madrid?
To plan your trip to New Madrid, search for places to stay and book flights and rental cars in advance. You can explore attractions like the New Madrid Historical Museum, Hunter-Dawson State Historic Site, and River Ridge Winery. For any outdoor activities, plan to enjoy them in the early morning or late afternoon.
Can I book a refundable hotel in New Madrid?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in New Madrid by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to New Madrid with Expedia?
Expedia makes it easier to plan your New Madrid trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in New Madrid?
The best choice depends on your travel style. Hotels in New Madrid can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my New Madrid trip on Expedia?
Once you've booked your New Madrid trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my New Madrid trip?
Expedia offers customer support before, during, and after your New Madrid trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to New Madrid?
If it's your first trip to New Madrid, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my New Madrid hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your New Madrid hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near New Madrid

A flock of birds flying over a field with bare trees in the background.

Tiptonville

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