Main South Vacations from $587

Book a Hotel + Flight or Car together to unlock savings

The Latest Main South Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Boston Lodge and Suites

Boston Lodge and Suites

Dorchester
$587
per person
Nov 3 - Nov 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
8.4/10 Very Good! (190 reviews)
Parking was not easy. It was advertised as free parming and the explanation made it seem simple enough but finding free street parking in the area is not easy and you co stantly have to move your vehicles.

Reviewed on May 19, 2026

Good Hotels Boston

Good Hotels Boston

South End
$1,545
per person
Sep 22 - Sep 29
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
8/10 Very Good! (55 reviews)
Very nice people and had excellent help!

Reviewed on Aug 7, 2026

Four Seasons Hotel Boston

Four Seasons Hotel Boston

Bay Village
Save 100% on your flight
$1,579
per person
Oct 21 - Oct 24
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
9.4/10 Exceptional! (475 reviews)
Overrated

Reviewed on Aug 10, 2026

Mandarin Oriental, Boston

Mandarin Oriental, Boston

Back Bay
Save 100% on your flight
$949
per person
Nov 5 - Nov 8
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Boston (BOS)
9.4/10 Exceptional! (440 reviews)
Sesuit Harbor House

Sesuit Harbor House

Save 100% on your flight
$842
per person
Oct 19 - Oct 24
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
9.6/10 Exceptional! (200 reviews)
This property is amazing! It’s so charming and has what anyone would want in a place to stay on the Cape. It’s situated in a great spot. Phil is incredibly lovely and helpful. I encourage anyone to consider staying at this property!

Reviewed on Aug 15, 2026

Where to stay in Main South

Find the best Main South areas and neighborhoods for the activities you enjoy most. Learn more about Main South
A historic building with a red brick facade and arched windows.

Worcester Central Business District

3 out of top 10 points of interest in this area

The second-largest city in Massachusetts is a lively hub of culture, with museums, theaters and galleries to explore between shopping and dining.

Find hotels in Worcester Central Business District
An indoor dining area with tables and chairs, large windows, and hanging light bulbs.

Shrewsbury Street

Shrewsbury Street might not have many top sights, but Union Station and EcoTarium are two attractions nearby that you can check out.

Find hotels in Shrewsbury Street
A red bridge over a calm lake with stone steps leading up to it.

Union HIll

While Union HIll isn't home to many top sights, Union Station and The Hanover Theatre for the Performing Arts are some notable places to visit nearby.

Find hotels in Union HIll
Default Image

Franklin Plantation

While Franklin Plantation isn't home to many top sights, EcoTarium and Union Station are some notable places to visit nearby.

Find hotels in Franklin Plantation
Default Image

Piedmont

If you're looking for some top things to see and do in Piedmont and surrounding area, you can visit The Hanover Theatre for the Performing Arts and Mechanics Hall.

Find hotels in Piedmont

Main South Hotel Deals

Publick House Historic Inn and Country Motor Lodge

Publick House Historic Inn and Country Motor Lodge

277 Main Street (RT 131) Sturbridge MA
Fully refundableReserve now, pay when you stay
$79 nightly
$89 total
Aug 24 - Aug 25
Total with taxes and fees
Publick House Historic Inn and Country Motor Lodge
Wellsworth Hotel

Wellsworth Hotel

14 Mechanic St Southbridge MA
Fully refundableReserve now, pay when you stay
$116 nightly
$130 total
Sep 15 - Sep 16
Total with taxes and fees
Wellsworth Hotel
Sonesta Select Boston Milford

Sonesta Select Boston Milford

10 Fortune Blvd Milford MA
Fully refundableReserve now, pay when you stay
$92 nightly
$103 total
Aug 31 - Sep 1
Total with taxes and fees
Sonesta Select Boston Milford
See all 343 properties in Main South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations
Golf Vacations
Golf Vacations
Luxury Vacations
Luxury Vacations
Romantic Vacations
Romantic Vacations
Ski Vacations
Ski Vacations
Gay Friendly Vacations
LGBTQ Friendly Vacations
LGBTQ Friendly Vacations
Adventure Vacations
Adventure Vacations
Vacations in Month
Where to go when
Where to go when
Honeymoon Vacations
Honeymoon Vacations
Mountain Vacations
Mountain Vacations
Fishing Vacations
Fishing Vacations
Adults Only Vacations
Adults Only Vacations
Waterpark Vacations
Waterpark Vacations
Scuba Diving Vacations
Scuba Diving Vacations
Yoga Vacations
Yoga Vacations
Cheap Vacations
Cheap Vacations
Solo Vacations
Solo Vacations

Stay near popular Main South attractions

Clark University

8.0/10 (184 reviews)
Enjoy the collegiate vibe when you visit Clark University, during your trip to Worcester. Experience the entertainment venues or attend a sporting event in this family-friendly area.
See properties

Burnside Fountain

After visiting Burnside Fountain, make a plan to see the other sights and activities in Worcester. Experience the entertainment venues and theater scene in this family-friendly area.
See properties
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.