Title: Main South Vacation Packages 2026 from $422 | Expedia.com

[Hotels in Main South](https://expedia.com/Main-South-Worcester-Hotels.0-n897567693610442752-0.Travel-Guide-Filter-Hotels)[Flights to Worcester](https://expedia.com/Cheap-Flights-To-Worcester.d6023336.Travel-Guide-Flights)[Things to do in Worcester](https://expedia.com/Things-To-Do-In-Worcester.d6023336.Travel-Guide-Activities)[Car Rentals in Main South](https://expedia.com/Car-Rentals-In-Main-South.d897567693610442752.Car-Rental-Guide)

![](https://images.trvl-media.com/place/897567693610442752/63b37654-a482-4124-a5d2-7c8eca44c94d.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Main South Vacations from $422

## Book a Hotel + Flight or Car together to unlock savings

- ##  
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Better together  
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- ###  
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Plan, book, and manage your trip all in one place

## The Latest Main South Vacation Packages

Price found within the past 48 hours. Click for updated prices.

![Boston Lodge and Suites](https://images.trvl-media.com/lodging/22000000/21340000/21333100/21333029/d2b7feac_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Boston Lodge and Suites

Dorchester

$422

per person

Mar 29 - Apr 1

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Boston (BOS)

8.4/10 Very Good! (188 reviews)

Apartment was clean and short walk from train. Staff were very friendly and helpful. Not too far from downtown Boston. Check in/check out process was very easy and convenient. If I ever find myself back in Boston, I’ll definitely see if this one is available.

Reviewed on Nov 10, 2025

![D. Hotel Suites & Spa](https://images.trvl-media.com/lodging/1000000/850000/849400/849303/5f3c4e34_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### D. Hotel Suites & Spa

Save 100% on your flight

$480

per person

Apr 21 - Apr 28

found 1 day ago

Roundtrip flight included

Chicago (CHI) to Boston (BOS)

9.4/10 Exceptional! (2,242 reviews)

There were many good things about the stay however; our room was super close to the interstate and the traffic and trucks starting rolling by at 5:30 am. I searched for earplugs and it was not conducive to easy sleep. I would not stay again unless the room was far away from the highway. Be forewarned. The people were super nice and the room was fine. Not great sleep was not!

Reviewed on Feb 27, 2026

![The Colonnade Hotel Back Bay](https://images.trvl-media.com/lodging/1000000/20000/12700/12660/f43e7537_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### The Colonnade Hotel Back Bay

Back Bay

Save 100% on your flight

$534

per person

Mar 29 - Apr 1

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Boston (BOS)

9.2/10 Wonderful! (2,268 reviews)

We stay at the Colonnade fairly regularly because of its convenient location and easy parking. This time we were stuck there because of a blizzard, so we spent more time actually hanging around the hotel. The lobby is really comfortable and cozy with a gas fire and a front wall of glass. The room was also very comfortable, including beds, pillows, bathrobes. We ate breakfast twice at the hotel restaurant and the staff were warm and friendly.

Reviewed on Feb 25, 2026

![Hotel UMass](https://images.trvl-media.com/lodging/1000000/490000/480800/480785/4e423f91_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel UMass

Save 100% on your flight

$712

per person

Apr 21 - Apr 28

found 1 day ago

Roundtrip flight included

Chicago (CHI) to Boston (BOS)

8.8/10 Excellent! (1,002 reviews)

Convenience of the location

Reviewed on Feb 24, 2026

![The Langham, Boston](https://images.trvl-media.com/lodging/1000000/10000/2600/2558/9a3ebe8a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### The Langham, Boston

Downtown Boston

Save 100% on your flight

$713

per person

Mar 29 - Apr 1

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Boston (BOS)

9.6/10 Exceptional! (1,004 reviews)

Friendly staff, clean room

Reviewed on Feb 20, 2026

## Where to stay in Main South

Find the best Main South areas and neighborhoods for the activities you enjoy most. [Learn more about Main South](https://expedia.com/Worcester-Main-South.dx897567693610442752)

![Worcester Central Business District showing heritage architecture and a city](https://images.trvl-media.com/place/553248635976482380/2aee2088-badf-4d17-8cbd-dbb4485148b4.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Worcester Central Business District

4 out of top 10 points of interest in this area

4/5(116 area reviews)

 The second-largest city in Massachusetts is a lively hub of culture, with museums, theaters and galleries to explore between shopping and dining. 

[Find hotel + flight trips in Worcester Central Business District](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Worcester%20Central%20Business%20District&DestID=553248635976482380&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![very cool space in old buick dealership. great flatbread pizza, great vibe.](https://images.trvl-media.com/place/6023336/052f3b3e-f954-4e2a-8e7d-ebab4c69ae91.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Shrewsbury Street

 Shrewsbury Street might not have many top sights, but Union Station and EcoTarium are two attractions nearby that you can check out. 

[Find hotel + flight trips in Shrewsbury Street](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Shrewsbury%20Street&DestID=897568218764566528&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Piedmont

 If you're looking for some top things to see and do in Piedmont and surrounding area, you can visit The Hanover Theatre for the Performing Arts and Mechanics Hall. 

[Find hotel + flight trips in Piedmont](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Piedmont&DestID=984769317615050752&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Franklin Plantation

 While Franklin Plantation isn't home to many top sights, EcoTarium and Union Station are some notable places to visit nearby. 

[Find hotel + flight trips in Franklin Plantation](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Franklin%20Plantation&DestID=553248635976477075&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Elm Park

 If you're looking for some top things to see and do in Elm Park and surrounding area, you can visit Mechanics Hall and Elm Park. 

[Find hotel + flight trips in Elm Park](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Elm%20Park&DestID=984768787933184000&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

## Main South Hotel Deals

![Spacious & Clean 3BR APT near Clark University](https://images.trvl-media.com/lodging/116000000/115820000/115814800/115814705/314704fc_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Spacious & Clean 3BR APT near Clark University

 Worcester MA

$196 nightly

$224 total

Mar 2 - Mar 3

Total with taxes and fees

10/10 Exceptional! (1 review)

Perfect apartment with lots of room; comfortable beds. Decorated with a personal touch (some VRBO's feel too impersonal) which made it very welcoming. Could not be better located for visiting Clark University campus!

Reviewed on Aug 30, 2025

[](https://expedia.com/Hotel-Search?startDate=3%2F2%2F2026&endDate=3%2F3%2F2026&selected=115814705&PinnedHotelID=115814705&HadPinnedHotel=true&regionId=897567693610442752)

![Wellsworth Hotel](https://images.trvl-media.com/lodging/1000000/900000/894300/894252/61dc8b11_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Wellsworth Hotel

14 Mechanic St Southbridge MA

Fully refundableReserve now, pay when you stay

$107 nightly

$120 total

Mar 12 - Mar 13

Total with taxes and fees

9.2/10 Wonderful! (1,433 reviews)

We love the Wellsworth. It’s very clean, friendly attentive employees, heated pool that’s actually warm, indoor basketball court which is cool and unique and tasty restaurant on site, we love the fish n chips!

Reviewed on Feb 22, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F12%2F2026&endDate=3%2F13%2F2026&selected=894252&PinnedHotelID=894252&HadPinnedHotel=true&regionId=897567693610442752)

![Embassy Suites by Hilton Boston Marlborough](https://images.trvl-media.com/lodging/1000000/30000/23000/22959/2c252d7a_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Embassy Suites by Hilton Boston Marlborough

123 Boston Post Rd W Marlborough MA

Fully refundableReserve now, pay when you stay

$108 nightly

$121 total

Mar 8 - Mar 9

Total with taxes and fees

9.2/10 Wonderful! (1,004 reviews)

Room and hotel was fine. There was just a loud alarm going off at 5 A.M. and kept going off. Called the front desk and also told them at checkout. Couldn't fall back asleep because of the alarm.

Reviewed on Feb 27, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=22959&PinnedHotelID=22959&HadPinnedHotel=true&regionId=897567693610442752)

[See all 346 properties in Main South](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F28%2F2026&endDate=3%2F1%2F2026&regionId=897567693610442752)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

### Discover the most popular places to visit in Main South

![Clark University and University Park aerial view with fall foliage in City of Worcester, Massachusetts MA, USA.](https://images.trvl-media.com/place/6069989/2bc70915-f0f5-4cdb-84c1-0659d9a43606.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Clark University

4.5/5(43 reviews)

Enjoy the collegiate vibe when you visit Clark University, during your trip to Worcester. Experience the entertainment venues or attend a sporting event in this family-friendly area. 

[](https://expedia.com/Clark-University-Main-South.d6069989.Vacation-Attraction)

![Union Station which includes a garden and a statue or sculpture](https://images.trvl-media.com/place/6070395/72178995-a0a5-4b6b-9b56-8cadfad2ac20.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Union Station

4.5/5(41 reviews)

Worcester’s picturesque transportation hub is also a popular tourist attraction with majestic architecture and a long history to learn about.

[](https://expedia.com/Union-Station-Worcester-Central-Business-District.d6070395.Vacation-Attraction)

![O'Kane Hall in College of the Holy Cross with fall foliage in city of Worcester, Massachusetts MA, USA.](https://images.trvl-media.com/place/6232670/e5c31d5a-3542-488b-933a-a9279b2d0b7b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### College of the Holy Cross

4.5/5(53 reviews)

Explore the campus of College of the Holy Cross, during your trip to Worcester. Experience the entertainment venues and theater scene in this family-friendly area. 

[](https://expedia.com/College-Of-The-Holy-Cross-Worcester.d6232670.Vacation-Attraction)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.