Main South Vacations from $621

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The Latest Main South Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Boston Lodge and Suites

Boston Lodge and Suites

Dorchester
$621
per person
Nov 2 - Nov 6
found 10 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Boston (BOS)
8.4/10 Very Good! (190 reviews)
Parking was not easy. It was advertised as free parming and the explanation made it seem simple enough but finding free street parking in the area is not easy and you co stantly have to move your vehicles.

Reviewed on May 19, 2026

Luxury Apartments by Hyatus at Boston Everett

Luxury Apartments by Hyatus at Boston Everett

$1,408
per person
Oct 15 - Oct 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
9/10 Wonderful! (6 reviews)
We were in Boston for the Mammoth March in Hingham and needed a base for some sight seeing in Boston for the week. We did not have a rental car but the parking garage was easily accessible and secure. We were able to get ubers very easily from the location. The Chelsea train station was only a 5 min walk away and the trains were reliable and efficient. The support staff replied to all our messages in the chat option quickly and were very helpful. The kitchen was well stocked and set up. The apartment was clean and all the linens and towels were freshly laundred. Would recommend this place without hesitation.

Reviewed on Jun 15, 2026

Iris Hotel Boston

Iris Hotel Boston

Coolidge Corner
Save 100% on your flight
$1,263
per person
Sep 22 - Sep 29
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
9.4/10 Exceptional! (612 reviews)
Very nice boutique with good amenities. Parking was easy,and close proximity to Fenway Park via MBTA . One complaint was the puffed up pillows for sleeping. Very uncomfortable. Also heavy comforter on beds in the summer. Next time would explore other hotels.

Reviewed on Aug 9, 2026

Good Hotels Boston

Good Hotels Boston

South End
Save 100% on your flight
$1,410
per person
Sep 22 - Sep 29
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
8/10 Very Good! (55 reviews)
Very nice people and had excellent help!

Reviewed on Aug 7, 2026

The Langham, Boston

The Langham, Boston

Downtown Boston
Save 100% on your flight
$994
per person
Sep 19 - Sep 22
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
9.6/10 Exceptional! (1,002 reviews)
Beautiful hotel in a perfect location in Boston. Quiet yet walkable to everything you might want from history to water to public transport. The staff are helpful and the bar is excellent

Reviewed on Aug 9, 2026

Where to stay in Main South

Find the best Main South areas and neighborhoods for the activities you enjoy most. Learn more about Main South
A historic building with a red brick facade and arched windows.

Worcester Central Business District

3 out of top 10 points of interest in this area

The second-largest city in Massachusetts is a lively hub of culture, with museums, theaters and galleries to explore between shopping and dining.

An indoor dining area with tables and chairs, large windows, and hanging light bulbs.

Shrewsbury Street

Shrewsbury Street might not have many top sights, but Union Station and EcoTarium are two attractions nearby that you can check out.

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Franklin Plantation

While Franklin Plantation isn't home to many top sights, EcoTarium and Union Station are some notable places to visit nearby.

A red bridge over a calm lake with stone steps leading up to it.

Union HIll

While Union HIll isn't home to many top sights, Union Station and The Hanover Theatre for the Performing Arts are some notable places to visit nearby.

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Piedmont

If you're looking for some top things to see and do in Piedmont and surrounding area, you can visit The Hanover Theatre for the Performing Arts and Mechanics Hall.

Main South Hotel Deals

Publick House Historic Inn and Country Motor Lodge

Publick House Historic Inn and Country Motor Lodge

277 Main Street (RT 131) Sturbridge MA
Fully refundableReserve now, pay when you stay
$88 nightly
$98 total
Aug 11 - Aug 12
Total with taxes and fees
9/10 Wonderful! (1,750 reviews)
"It was a great all-in-one stop after a long day’s drive."

Reviewed on Aug 9, 2026

Publick House Historic Inn and Country Motor Lodge
Wellsworth Hotel

Wellsworth Hotel

14 Mechanic St Southbridge MA
Fully refundableReserve now, pay when you stay
$116 nightly
$130 total
Sep 6 - Sep 7
Total with taxes and fees
Wellsworth Hotel
Sonesta Select Boston Milford

Sonesta Select Boston Milford

10 Fortune Blvd Milford MA
Fully refundableReserve now, pay when you stay
$92 nightly
$103 total
Aug 16 - Aug 17
Total with taxes and fees
7.8/10 Good! (1,025 reviews)
"There was no breakfast included."

Reviewed on Aug 9, 2026

Sonesta Select Boston Milford
See all 346 properties in Main South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Main South attractions

Clark University

8.0/10 (184 reviews)
Enjoy the collegiate vibe when you visit Clark University, during your trip to Worcester. Experience the entertainment venues or attend a sporting event in this family-friendly area.
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Burnside Fountain

After visiting Burnside Fountain, make a plan to see the other sights and activities in Worcester. Experience the entertainment venues and theater scene in this family-friendly area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.