Main South, MA
Worcester
Visit Main South
Stay near popular Main South attractions
Things to do
New England Botanic Garden Day Trip from Boston
$72
per adult
Main South Hotel Deals
Sonesta Select Boston Milford
10 Fortune Blvd Milford MA
$94 nightly
The price is $105 total per night from Nov 1 to Nov 2
$105 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Milford. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
7.6/10 Good! (1,000 reviews)
"The room was fine. The screen was not attached to the balcony. The latch to the door locked me out of the room twice. Maintenance had to come remove the latch. Overall, the state was fine. I would stay again."
Reviewed on Oct 26, 2026
Publick House Historic Inn and Country Motor Lodge
277 Main Street (RT 131) Sturbridge MA
$79 nightly
The price is $88 total per night from Nov 2 to Nov 3
$88 total
Nov 2 - Nov 3
Total with taxes and fees
Book a stay at this spa resort in Sturbridge. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
Motel 6 Framingham, MA - Boston West
1668 Worcester Rd Framingham MA
$96 nightly
The price is $107 total per night from Nov 16 to Nov 17
$107 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this motel in Framingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Wellsworth Hotel
14 Mechanic St Southbridge MA
$96 nightly
The price is $108 total per night from Nov 22 to Nov 23
$108 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Southbridge. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (1,706 reviews)
"Everything was nice. A little disappointed that the bar closed at 10:00 since we got in around 10:30."
Reviewed on Oct 27, 2026
Best Western Royal Plaza Hotel & Trade Center
181 Boston Post Rd W Marlborough MA
$88 nightly
The price is $98 total per night from Nov 24 to Nov 25
$98 total
Nov 24 - Nov 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful ...
DoubleTree by Hilton Hotel Boston - Westborough
5400 Computer Dr Westborough MA
$114 nightly
The price is $127 total per night from Nov 5 to Nov 6
$127 total
Nov 5 - Nov 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Westborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Main South
Find the best Main South areas and neighborhoods for the activities you enjoy most.
Worcester Central Business District
If you're spending some time in Worcester Central Business District, DCU Center and Mechanics Hall are top sights worth seeing.
Union HIll
While Union HIll isn't home to many top sights, Union Station and The Hanover Theatre for the Performing Arts are some notable places to visit nearby.
Photo by Lisa Frackiewicz
Open Photo by Lisa Frackiewicz
Shrewsbury Street
Shrewsbury Street might not have many top sights, but Union Station and DCU Center are two attractions nearby that you can check out.
Photo by Paula Jellison
Open Photo by Paula Jellison
Canal District
If you're looking for some top things to see and do in Canal District and surrounding area, you can visit Union Station and The Hanover Theatre for the Performing Arts.
Franklin Plantation
While Franklin Plantation isn't home to many top sights, Union Station and EcoTarium are some notable places to visit nearby.