Main Street Vacations from $182

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Your Main Street Vacation

From its bars and pubs to its culture and dining, there are plenty of convincing reasons to book a vacation package to Main Street. When it's time to escape from it all, this urban neighborhood has a spot just for you. Some leading nearby attractions to check out during your trip to Main Street include University of Michigan, Michigan Stadium and University of Michigan Museum of Art. Expedia can put your travel plans into action. Book your ultimate Main Street vacation now.

The Latest Main Street Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Radisson Hotel Detroit Metro Airport

Radisson Hotel Detroit Metro Airport

3 out of 5
Price was $260, price is now $182 per person
$182
per person
Oct 16 - Oct 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Detroit (DTW)
7/10 Good! (1,027 reviews)
Close to the DTW airport.

Reviewed on Sep 1, 2025

Downtown Detroit Apartments by Landing

Downtown Detroit Apartments by Landing

4 out of 5
Downtown Detroit
Save 100% on your flight
Price was $918, price is now $645 per person
$645
per person
Oct 21 - Oct 28
found 10 hours ago
Roundtrip flight included
New York (JFK) to Detroit (DTW)
No reviews
420 Oasis

420 Oasis

2 out of 5
Save 100% on your flight
Price was $925, price is now $652 per person
$652
per person
Oct 14 - Oct 19
found 1 day ago
Roundtrip flight included
New York (JFK) to Detroit (DTW)
No reviews
Royal Park Hotel

Royal Park Hotel

4 out of 5
Save 100% on your flight
Price was $776, price is now $548 per person
$548
per person
Oct 16 - Oct 19
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Detroit (DTW)
9.2/10 Wonderful! (1,005 reviews)
Finest hotel in Rochester. clean and well managed. I will be back.

Reviewed on Sep 2, 2025

Daxton Hotel Birmingham, Curio Collection by Hilton

Daxton Hotel Birmingham, Curio Collection by Hilton

4 out of 5
Save 100% on your flight
Price was $960, price is now $732 per person
$732
per person
Oct 16 - Oct 19
found 16 hours ago
Roundtrip flight included
Baltimore (BWI) to Detroit (DTW)
9.2/10 Wonderful! (487 reviews)
Temporary construction makes access difficult but once resolve the rest has been 5 out of 5

Reviewed on Aug 31, 2025

Where to stay in Main Street

Find the best Main Street areas and neighborhoods for the activities you enjoy most. Learn more about Main Street
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South Central

3 out of top 10 points of interest in this area

While visiting South Central, you might make a stop by sights like Yost Ice Arena and Michigan Stadium.

Find hotels in South Central

Main Street Hotel Deals

Wyndham Garden Ann Arbor

Wyndham Garden Ann Arbor

3 out of 5
2900 Jackson Ave, Ann Arbor, MI
$75 nightly
The price is $83 total per night from Sep 14 to Sep 15
$83 total
Sep 14 - Sep 15
Total with taxes and fees
Wyndham Garden Ann Arbor
Weber's Hotel & Restaurant

Weber's Hotel & Restaurant

4 out of 5
3050 Jackson Road, Ann Arbor, MI
$159 nightly
The price is $176 total per night from Sep 28 to Sep 29
$176 total
Sep 28 - Sep 29
Total with taxes and fees
9.2/10 Wonderful! (1,269 reviews)
"We took a quick getaway and just loved this place. Pool hot tub and sauna, all indoor. Just can't wait to go back"

Reviewed on Aug 29, 2025

Weber's Hotel & Restaurant
Red Roof Inn Ann Arbor - U of Michigan South

Red Roof Inn Ann Arbor - U of Michigan South

2 out of 5
3505 S State St, Ann Arbor, MI
$62 nightly
The price is $69 total per night from Sep 6 to Sep 7
$69 total
Sep 6 - Sep 7
Total with taxes and fees
Red Roof Inn Ann Arbor - U of Michigan South
See all 662 properties in Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Main Street

University of Michigan as well as a couple

University of Michigan

4.5/5(1,101 reviews)

Come to see the ivied halls, grassy quads, cultural performances and athletic events at this renowned university, one of the world’s most prestigious.

University of Michigan
Michigan Football.

Michigan Stadium

4.5/5(445 reviews)

Catch an event at Michigan Stadium during your trip to Ann Arbor. Experience the area's lively festivals or attend a sporting event.

Michigan Stadium
University of Michigan Museum of Art showing modern architecture as well as a couple

University of Michigan Museum of Art

4.5/5(130 reviews)

Browse one of the nation’s greatest and oldest university art collections at this museum on the prestigious University of Michigan campus.

University of Michigan Museum of Art
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.