
Main Street Vacations from $361
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Your Main Street Vacation
From its bars and pubs to its culture and dining, there are plenty of convincing reasons to book a vacation package to Main Street. When it's time to escape from it all, this urban neighborhood has a spot just for you. Some leading nearby attractions to check out during your trip to Main Street include University of Michigan, Michigan Stadium and University of Michigan Museum of Art. Expedia can put your travel plans into action. Book your ultimate Main Street vacation now.
The Latest Main Street Vacation Packages
Price found within the past 48 hours. Click for updated prices.


Saint John's Resort
Price was $1,200, price is now $629 per person
$629
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Detroit (DTW)
9.6/10 Exceptional! (1,006 reviews)
Upon walking in the front door, there are smiles and welcoming staff no matter what time you arrive. The rooms are fully stocked with anything you might need. The restaurant is top tier! The cleanliness of this hotel is second to none!! It is the nicest maintained hotel that I have ever stayed in. We love it here!
Reviewed on Jul 29, 2026

Ann Arbor North Inn
Thurston
Save 100% on your flight
Price was $587, price is now $408 per person
$408
per person
Sep 4 - Sep 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Detroit (DTW)
7.8/10 Good! (1,051 reviews)
The building as a whole was rundown, but the room was nice. The air conditioning was excellent and everything in the room was very clean and well taken care of. The bed and pillows were very comfortable. Too bad the hallways looked so rough.
Reviewed on Jul 30, 2026


Hotel Chataura
Price was $569, price is now $419 per person
$419
per person
Sep 22 - Sep 29
found 1 day ago
Roundtrip flight included
New York (JFK) to Detroit (DTW)
4.8/10 (344 reviews)
I had the worst time the power without when I asked about. When will the power be coming back on? They had a young teenager at the desk telling me, I had to wait until Monday to talk to a manager. This was on Friday, July 3rd, there was no power in the room. You\n Could not even use the shower cause the water was cold. So when I tried to talk to the manager that followed week before I checked out on that Tuesday, I was told that I should have checked out that Friday when I had flew in from San Francisco and they will not refund. My money , because I ordered online so since they were so insensitive in how they treated me, I did contact my lawyer and the Better Business Bureau and I am going to contact anybody I can because I felt I was given injustice for a room that I could not take a shower in. Are relax in because of no power and no hot water. They told me was because of the storm they were coming in and out, but more than half the hotel was still lit up and when I looked at rules from outside their rooms were still they're on power was still on in their rooms. So that lets me know that there was something wrong with the idea that I flew in from out of town , and they could not accommodate me with a rule that works
Reviewed on Jul 29, 2026
Where to stay in Main Street
Find the best Main Street areas and neighborhoods for the activities you enjoy most. Learn more about Main Street

South Central
3 out of top 10 points of interest in this area
While visiting South Central, you might make a stop by sights like Michigan Stadium and Yost Ice Arena.
Main Street Hotel Deals

Wyndham Garden Ann Arbor
2900 Jackson Ave Ann Arbor MI
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Aug 2 to Aug 3
$88 total
Aug 2 - Aug 3
Total with taxes and fees
7.2/10 Good! (1,512 reviews)
"Hotel was dated"
Reviewed on Jul 31, 2026

Weber's Hotel & Restaurant
3050 Jackson Road Ann Arbor MI
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $188 total per night from Aug 3 to Aug 4
$188 total
Aug 3 - Aug 4
Total with taxes and fees

Ann Arbor North Inn
2300 Green Road Ann Arbor MI
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $104 total per night from Aug 10 to Aug 11
$104 total
Aug 10 - Aug 11
Total with taxes and fees
7.8/10 Good! (1,055 reviews)
"The building as a whole was rundown, but the room was nice. The air conditioning was excellent and everything in the room was very clean and well taken care of. The bed and pillows were very comfortable. Too bad the hallways looked so rough."
Reviewed on Jul 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do

Italian Pasta Cooking Class in Detroit (Includes 3-Course Meal)
$129
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.






















