The best area to stay in Manicoré is near the city center, particularly along the Madeira River waterfront.
This central area is the hub of activity in Manicoré. It's where you'll find most of the local businesses, eateries, and basic services. The waterfront offers views of the Madeira River, which is a key part of daily life and transportation in the region. The main thoroughfares, like Avenida Eduardo Ribeiro and Avenida Getúlio Vargas, crisscross this area. Independent travelers will find this area convenient for accessing local transportation and experiencing the town's daily rhythm.
For those planning excursions into the surrounding Amazon rainforest, staying close to the riverfront is especially beneficial. Many local guides and boat operators depart from this area, making it an efficient base for exploring the natural environment.