Masargantupo Vacations from $745

Book a Hotel + Flight or Car together to unlock savings

Your Masargantupo Vacation

The vibrant city of Masargantupo is calling your name. Uncover both its hidden gems and highlights with a Masargantupo vacation package that's tailored to you. When it's time to get out and see the sights, be sure to put Cayos Holandeses and Museum of the Kuna Nation on the to-do list for your trip to Masargantupo. Expedia is here to help you escape your daily routine. Tailor your vacation to Masargantupo to suit your travel style, whatever that may be.

The Latest Masargantupo vacation packages

Price found within the past 48 hours. Click for updated prices.
Kooteja Anton Valley ËRA

Kooteja Anton Valley ËRA

2 out of 5
Save 100% on your flight
Price was $1,266, price is now $745 per person
$745
per person
Jan 1 - Jan 8
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
6/10 (2 reviews)
Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
Price was $2,131, price is now $1,140 per person
$1,140
per person
Nov 19 - Nov 23
found 8 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
No reviews
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $3,226, price is now $1,985 per person
$1,985
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (997 reviews)
I like everything have a good service and the property installation have a good maintenance .

Reviewed on Oct 13, 2025

Mahogany Suites

Mahogany Suites

2 out of 5
Price was $2,000, price is now $1,306 per person
$1,306
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
No reviews
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Price was $2,197, price is now $1,526 per person
$1,526
per person
Dec 26 - Dec 30
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.8/10 Exceptional! (21 reviews)
It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment.

Reviewed on Jul 23, 2025

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See all available trips from Columbus to Masargantupo
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Discover the most popular places to visit in Masargantupo

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Masargantupo. Stroll along the seaside or experience the area's festivals.

Museum of the Kuna Nation

Porvenir Museum

You can spend time browsing the exhibits at Porvenir Museum during your travels in Narganá. Amble around the area's seaside or experience its festivals.

Porvenir Museum

What to do in Masargantupo

San Blas Money Heist Island Day tour - Visit 3-islands + Natural Pool

San Blas Money Heist Island Day tour - Visit 3-islands + Natural Pool

$76
per adult
San Blas Money Heist Island Day tour - Visit 3-islands + Natural Pool
Discover the San Blas Islands in one day

Discover the San Blas Islands in one day (3 islands)

$71
per adult
Discover the San Blas Islands in one day (3 islands)
Eco Agro Adventure with Horseback Riding in a Private Ranch

Eco Agro Adventure with Horseback Riding in a Private Ranch

$75
per adult
Eco Agro Adventure with Horseback Riding in a Private Ranch
See all activities in Masargantupo

Masargantupo Hotel Deals

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

2 out of 5
Diablo Island, Narganá, Guna Yala
$188 nightly
The price is $207 total per night from Oct 16 to Oct 17
$207 total
Oct 16 - Oct 17
Total with taxes and fees
Private Ocean-Front Cabin with private bathroom on San Blas Island
San Blas Paradise Private Cabins on Shipwreck Island - meals included

San Blas Paradise Private Cabins on Shipwreck Island - meals included

2 out of 5
Perro Island, Narganá, Guna Yala
Get rates
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Private Over the Water Cabin on San Blas Island

Private Over the Water Cabin on San Blas Island

2 out of 5
9.542876, -78.899058, Narganá, San Blas
7/10 Good! (6 reviews)
"Very nice. And I liked the food"

Reviewed on Aug 14, 2025

Get rates
Private Over the Water Cabin on San Blas Island
See all 59 properties in Masargantupo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Masargantupo Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Max Temp Winter
80ºF
Max Temp Summer
80ºF
Top Sights
Museum of the Kuna Nation and Cayos Holandeses

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Frequently asked questions

How much does a Masargantupo vacation package cost?
You can grab a vacation package to this popular destination from $745 on Expedia. But how much your vacation to Masargantupo costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Masargantupo?
If you're looking to book a cheap Masargantupo vacation package, consider planning a trip in May, June and July. You'll typically find better rates on accommodations and flights during these months — ideal for a budget-friendly getaway.
How many days is enough for Masargantupo?
With a well-organized itinerary, you can easily hit the main Masargantupo attractions in a handful of days. But if you want to explore off the beaten track or go on day trips, consider booking your Masargantupo vacation for longer.
How to find the best Masargantupo package deals?
Start your search for a Masargantupo package deal by entering your preferred trip dates and destination under our "Packages" tab. Then add some filters, like "Property type" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the ideal Masargantupo package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Masargantupo escape underway.
Is it cheaper to book a Masargantupo vacation as a package?
An Expedia vacation package could land you great savings when compared to booking hotels and flights individually. Better still, you can personalize your Masargantupo getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to Masargantupo?
If you have your Masargantupo travel dates confirmed, book as soon as you can to score some unbeatable deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are great for setting off on a whim.
Does Expedia offer Book Now, Pay Later Masargantupo vacation packages?
Your Masargantupo break should be a relaxing escape from your busy life, not a source of money-related stress. So to give you a little more flexibility, we've partnered with online lender Affirm to offer our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.