Panama Vacations & Trips from $549

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Your Panama Vacation

Reserve a vacation package to Panama and make travel planning quick and easy. With the finer details organized before you leave, you can focus on enjoying every moment in this destination. Your trip to Panama wouldn't be complete without exploring some of its best cities, starting with Tocumen. Some of the top attractions here include Metromall Panama and Los Pueblos Commercial Center. Rio Hato should also be on the itineraries of all Panama travelers. Visitors to this city love Playa Blanca and Santa Clara Beach. When you're ready to stop dreaming and start doing, Expedia will help turn your Panama vacation into reality.

Top destinations in Panama

The Latest Panama Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Panamonte
Casa Fofo
Central Hotel Bocas del Toro
Ciel y Miel
Mahogany Suites

Best Places to Vacation in Panama

1. Plan your dream getaway to Panama City

Panama City in Panama offers a vibrant and diverse atmosphere for families looking for a memorable vacation. With its stunning skyscrapers, scenic views, and bustling streets, there is plenty to explore and enjoy. Whether it's shopping at local markets, dining at delicious restaurants, or trying your luck at the casinos, Panama City has something for everyone. Families can also enjoy tours and sightseeing activities to discover the rich history and culture of the city. From exploring the Panama Canal to dancing the night away at lively bars, Panama City promises an unforgettable experience for families.

  • The peak season is from July to September
  • The off-peak season is from October to December
  • Travelers tend to stay 3 days in Panama City

2. Enjoy Rio Hato with a travel package

Rio Hato, located in Coclé, Panama, offers a unique and diverse atmosphere perfect for a beach vacation. With its stunning beaches and beautiful sunrises, it is an ideal destination for relaxation and recreation. The local art scene and family-friendly activities provide entertainment for all ages, while festivals throughout the year showcase the vibrant culture of the area. Whether you're looking for a romantic getaway or a fun-filled adventure, Rio Hato has something for everyone. Enjoy the sea, explore the local bars, and immerse yourself in the warm and welcoming atmosphere of this coastal paradise.

  • The peak season is from January to March
  • The off-peak season is from August to October
  • Travelers tend to stay 3 days in Rio Hato

3. Discover Bocas del Toro with our vacation deals

Bocas del Toro in the Bocas del Toro Province of Panama offers a vibrant and diverse atmosphere for outdoor enthusiasts. With its stunning beaches, picturesque islands, and crystal-clear waters, it is a paradise for activities such as scuba diving and snorkeling. The local culture is rich, with live music and dancing adding to the lively atmosphere. Vacation packages are popular among travelers, offering a range of tours and experiences. Whether you're looking for relaxation or adventure, Bocas del Toro has something to offer for everyone.

  • The peak season is from January to March
  • The off-peak season is from October to December
  • Travelers tend to stay 3 days in Bocas del Toro

4. Find your perfect Boquete vacation

Boquete, located in the Chiriquí Province of Panama, offers a unique outdoor vacation experience. With its ideal geography, visitors can enjoy activities such as coffee tours, hiking, rafting, and ziplining. The area is known for its breathtaking volcanoes and stunning natural surroundings, making it a haven for adventure and nature enthusiasts. In addition to outdoor activities, Boquete also offers a wide range of dining options, allowing travelers to indulge in local cuisine. The popular traveler activities in Boquete include destination activities and various things to do, ensuring that visitors have a memorable and fulfilling vacation.

  • The peak season is from January to March
  • The off-peak season is from May to July
  • Travelers tend to stay 3 days in Boquete

6. Book your ideal Colon with a vacation package

Colon, Colon, Panama offers a diverse range of experiences for families on vacation. Whether you're in the mood for shopping, relaxation, or enjoying family-friendly activities, Colon has it all. With its secluded hunting spots, beautiful lakes, and abundant wildlife, nature enthusiasts will be in their element. The lush jungles provide a perfect backdrop for fishing and swimming adventures. For those looking to explore the ocean, there are exciting options like cruises and ocean cruises. Colon truly has something for everyone, making it an ideal destination for a memorable family vacation.

  • The peak season is from January to March
  • The off-peak season is from October to December
  • Travelers tend to stay 3 days in Colon

5. Experience Veracruz with a travel package

Veracruz in Panamá Oeste Province, Panama, offers a perfect atmosphere for a family vacation. With its secluded beaches, delicious seafood, and relaxing ambiance, it is an ideal destination. You can enjoy exciting excursions and explore the stunning coastline while indulging in fresh seafood. Veracruz is also known for its vacation packages, which cater to the needs of travelers. Whether you want to unwind on the beach or savor a delightful dining experience, Veracruz has it all. Don't miss the chance to create unforgettable memories with your family in this beautiful coastal town.

  • The peak season is from December to February
  • The off-peak season is from May to July
  • Travelers tend to stay 3 days in Veracruz

Find the Best Panama Vacation Packages

Panama Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Population
3,864,200
Top Sights
Cinta Costera, Venao Beach and Sleeping Indian Girl

Panama Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $126 total per night from Nov 10 to Nov 11
$126 total
Nov 10 - Nov 11
Total with taxes and fees
9/10 Wonderful! (4,433 reviews)
.

Reviewed on Oct 27, 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
$121 nightly
The price is $133 total per night from Nov 1 to Nov 2
$133 total
Nov 1 - Nov 2
Total with taxes and fees
8.4/10 Very Good! (2,272 reviews)
It was a nice property

Reviewed on Oct 28, 2025

Crowne Plaza Panama Airport by IHG
Gran Evenia Bijao & Convention Center

Gran Evenia Bijao & Convention Center

3.5 out of 5
Carretera Interamericana km 108, Rio Hato
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $152 total per night from Oct 30 to Oct 31
$152 total
Oct 30 - Oct 31
Total with taxes and fees
7.8/10 Good! (997 reviews)
Nice experience

Reviewed on Oct 23, 2025

Gran Evenia Bijao & Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Panama vacation package cost?
Say yes to new adventures with our Panama vacation packages, which start from only $549. Pick the flights and hotels that suit your style. Then, add on some tours or activities to cap off your unique adventure.
How do I get a cheap travel package to Panama?
Booking a hotel and flight together with Expedia won't just save you time — it'll save you a nice amount too. A Panama vacation package makes it a cinch to arrange the ideal trip. With more than 550 airlines all over the world to pick from, finding convenient flights that fit your schedule won't be an issue. On top of that, we've got over 1,000,000 hotel options globally to choose from. Now that's choice! Whatever your budget, Expedia puts more of the world within your reach.
Where should I stay in Panama?
To see terrific sights like Miraflores Locks and Metropolitan Cathedral of Panama, Panama City is the place to be. Plenty of travelers also enjoy spending time in Panama Canal Zone, home to Miraflores Locks and Gatun Locks. If you've got an extended vacation in Panama, why not check out both cities?
What are the top hotels in Panama?
Look up Hotel Riu Plaza Panama and Crowne Plaza Panama Airport, an IHG Hotel. They're the first choice for many travelers headed to Panama City. If Bocas del Toro features in your travel itinerary, Divers Paradise Boutique Hotel and La Coralina Island House are both top-notch options.
How far in advance should I book my Panama vacation?
Reserving your seat early with Expedia means one less thing to have to worry about. Most air carriers display prices up to 12 months in advance. This is generally the cheapest time to book. If circumstances have left you booking late, low prices to Panama sometimes occur a few weeks before departure.
What does an Expedia Panama travel package include?
That depends on what you're after. If you're traveling solo, you might decide to combine flights and hotels. Taking the whole family to Panama? A travel package including rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to tailor your travel package.
What should I know before booking a Panama travel package?
You'll enjoy amazing savings when you combine your hotels, flights and rental cars into a package. Plus, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Panama Expedia vacation package?
Yes — that's one of the best things about an Expedia package. You get to choose. We have more than 550 airline partners globally, so you have options galore when creating your Panama getaway.
Does Expedia offer Book Now, Pay Later Panama vacation packages?
Having teamed up with online lender Affirm, Expedia provides financial flexibility with a Book Now, Pay Later option for hotel and activities packages. Get the money side of things out of the way with an upfront payment or split the cost of your getaway over multiple installments. There's a payment option to suit every wanderer.
If I'm not able to travel, can I cancel my Panama vacation package?
Because we understand life is full of surprises, the answer is yes. For further information, check out our Customer Service Portal. But generally speaking, if you've booked your package in the last 24 hours, you may be able to change or cancel it without penalty. Your airline, hotel or car rental company may charge a fee if your booking is older than that.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.