Panama Vacations & Trips

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Choose one or more items to build your trip:

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Enjoy flexibility with our Book now Pay later option & fully refundable rates on most hotels

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Top destinations in Panama

Panama Flight and Hotel Deals

Amarla Boutique Hotel Casco Viejo
Gamboa Rainforest Reserve
The Executive Hotel
Hotel Caribe
Los Establos Boutique Resort- All Inclusive

Panama Vacation

While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.

Panama Hotel + Flights

Expedia has 1846 hotels available here starting at $81 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Vacation Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavors like ceviche?

Your Panama Vacation Itinerary

  • Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colorful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.

  • Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.

  • Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.

Panama Information

  • Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.

  • If you’ll be spending most of your time in the nation’s capital, check out our Panama City Vacation Packages.

  • Want to really experience the carefree vibe of this Latin American gem? Book one of our Panama All Inclusive Resorts and say adios to vacation planning stress.

Panama Hotel Deals

Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama, 81606579
Fully refundableReserve now, pay when you stay
The price is $81 per night from Dec 4 to Dec 5
$81
per night
Dec 4 - Dec 5
4.2/5 Very Good! (1,000 reviews)
"Everything was great"

Reviewed on Nov 25, 2022

Plaza Paitilla Inn Hotel
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
4 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is $97 per night from Dec 8 to Dec 9
$97
per night
Dec 8 - Dec 9
4.4/5 Wonderful! (1,018 reviews)
"The size of the room and bathroom is huge. The complimentary breakfast has so many food and drinks. The location is convenient to the new city and old town."

Reviewed on Nov 27, 2022

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport
Crowne Plaza Panama Airport
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama, 816016660
Fully refundable
The price is $115 per night from Dec 4 to Dec 5
$115
per night
Dec 4 - Dec 5
4.1/5 Very Good! (1,113 reviews)
"Hospedaje del 25 al 28 noviembre. Variedad en el desayuno. No tienen nevera en las habitaciones para poder mantener agua o refrigerios."

Reviewed on Nov 29, 2022

Crowne Plaza Panama Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Panama vacation package cost?
The cheapest Panama vacation package is $558, so the trip of your dreams can become a reality — without the high price tag. Bundle flights, hotels and car rentals to customize a package that suits your travel style.
If I'm not able to travel, can I cancel my Panama vacation package?
We totally get it — sometimes life doesn’t go according to plan. If you’ve booked a Panama vacation package and have to cancel or amend it, we can help. It’s always worth having a look at our Customer Service Portal first for information. But in general, if you’ve booked your package in the last 24 hours, you may be able to cancel or change your itinerary for free. If it’s more than 24 hours, your airline, hotel or car rental company may impose a fee.
How do I get a cheap travel package to Panama?
Combine your flights and hotels, add on extras such as activities or a rental car, and save up to $366. A Panama vacation package makes getting away on a budget a walk in the park. You won’t just pick up exciting discounts on your adventure — you’ll have a world of choice within in your grasp too. When you book with Expedia, you’ll have your pick of over 550 airlines and 1,000,000 properties around the globe. Your next big adventure starts right here, right now!
Where should I stay in Panama?
Panama City is a great place to explore. It attracts many visitors who come to check out its biggest sights, like Metropolitan Cathedral of Panama and Miraflores Locks.
What are the top hotels in Panama?
The Executive Hotel and JW Marriott Panama know how to make their guests feel at home in Panama City. If you also plan to visit Bocas del Toro, take a look at Punta Caracol Acqua Lodge and Azul Paradise Bocas Town. Both are top picks with travelers.
When is the best time of year to visit Panama?
If saving money is a priority, is the best time to escape to Panama. is typically the priciest month, so you’ll need a bigger travel budget if you visit then. are the peak season months and when this destination is often at its most exciting. Clear space in your calendar for if you’d prefer a quieter vacation.
How far in advance should I book my Panama vacation?
Savvy travelers often reserve their seats early. You can generally look up international airfares on Expedia up to a year before your flight. If you’re purchasing tickets last minute, don’t stress. Low prices sometimes appear in the last weeks prior to departure.
What does an Expedia Panama travel package include?
From hotels and flights to rental cars, Expedia can help you create a Panama package that’s right for you. Vacationing for a week or longer? Look into a flight, rental car and hotel bundle. If you’re taking a quick break, a hotel and airfare deal could be what you’re after. Tours and activities can be added after you’ve booked. Our packages make it a breeze to save and plan.
What should I know before booking a Panama travel package?
A travel package can be customized for your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Hotels, rental cars and flights — mix and match whatever combination suits your style.
Does Expedia offer Book Now, Pay Later Panama vacation packages?
Thanks to the combined efforts of Expedia and online lender Affirm, you can split the price of your package booking over a number of payments. For financial freedom, take advantage of our Book Now, Pay Later option and figure out a payment arrangement that matches your circumstances.
Can I choose my airline with a Panama Expedia vacation package?
With a vacation package, you’re in charge. Whether you’re looking to fly to Panama in economy or business class, simply pick from the available airline options. Expedia has access to more than 550 airline partners worldwide.
Can I travel to Panama right now?
Our Covid-19 Travel Advisor is the place to go for up-to-date information regarding quarantine policies and travel restrictions for Panama. Get clued up before you take off!

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