Panama may have travel restrictions in place due to COVID-19.

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Panama Vacation Packages

Choose two or more items and save on your trip:

Panama Vacation: Coronavirus Information

Most Panama hotels offer free cancellation. Consider booking refundable hotels rather than non-refundable ones. Just look for the ‘free cancellation’ message during your hotel search. Prices can vary, but right now we believe that flexibility matters.

For more information about the impact of COVID-19 on your Panama trip, please visit our Coronavirus Information page (opens in new window).

Top Panama Flight + Hotel Deals

Riu Playa Blanca - All Inclusive
 Royal Decameron Panama All Inclusive
Punta Caracol Acqua Lodge
Summit Rainforest & Golf Resort
Marriott Executive Apartments Panama City, Finisterre
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2021 Panama vacation deals

The Westin Playa Bonita Panama
Toscana Inn
Valle Escondido Resort Golf and Spa
Las Olas Resort
Hotel California Panama
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Top Hotels in Panama

Principe Hotel and Suites
Principe Hotel and Suites
3 out of 5
Via Argentina, Panama City, Panama
Free CancellationReserve now, pay when you stay
The price is $49 per night from Oct 26 to Oct 27
4.2/5Very Good! (416 reviews)

"Centrico y atentos. El acceso es muy bueno y el rest de sushi"…"

Reviewed on Aug 17, 2020

Principe Hotel and Suites
Hyatt Place Panama City/Downtown
Hyatt Place Panama City/Downtown
3.5 out of 5
Avenida Aquilino de la Guardia, between, Vía España and Calle 52 Bella Vista, Panama City, Panama
4.3/5Excellent! (1,000 reviews)
Good location

"Hotel is a little worn but walking distance to restaurants. Has coin laundry on pool level which is great for multiweek travelers. Would.stay again."…"

Reviewed on Mar 10, 2020

Hyatt Place Panama City/Downtown
Hilton Panama
Hilton Panama
5 out of 5
Balboa Ave. and Aquilino De La Guardia, Panama City, Panama
Free CancellationReserve now, pay when you stay
The price is $110 per night from Nov 6 to Nov 7
4.4/5Excellent! (604 reviews)

"Great location and very clean. Confusing elevator system. Expensive drinks."…"

Reviewed on Apr 1, 2020

Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top things to do in Panama

Dinner & Folkloric Show
Image for Dinner & Folkloric Show

Dinner & Folkloric Show

Per adult
74% of travellers recommend
Private Bedroom in San Blas Islands - Escape into Paradise!!
Image for Private Bedroom in San Blas Islands - Escape into Paradise!!

Private Bedroom in San Blas Islands - Escape into Paradise!!

Per adult
Ancon Hill / Mi-Pueblito Village
Image for Ancon Hill / Mi-Pueblito Village

Ancon Hill / Mi-Pueblito Village

Per adult

Panama Hotel + Flights

Panama Vacation

While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.

Panama Hotel + Flights

Expedia has 1597 hotels available here starting at $49 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Vacation Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavors like ceviche?

Your Panama Vacation Itinerary

Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colorful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.

Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.

Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.

Panama Information

Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.

If you’ll be spending most of your time in the nation’s capital, check out our Panama City Vacation Packages .

Want to really experience the carefree vibe of this Latin American gem? Book one of our Panama All Inclusive Resorts and say adios to vacation planning stress.

Frequently asked questions

How much does a Panama vacation package cost?
Get ready to book, because a getaway to Panama starts from an affordable $382. When you bundle your hotels, flights and car rentals into a package, you’ll land the biggest bargains.
If I'm not able to travel, can I cancel my Panama vacation package?
It’s difficult to predict what the future holds, so it’s good to know that you can change or cancel your Panama vacation package. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Visit our Customer Service Portal for more information.
How do I get a cheap travel package to Panama?
Think of all the thrilling things you could do in Panama with an extra $583. If you bundle your hotel and flights into a package, that’s the amount you could save! You have so much choice with Expedia. In fact, you can choose from over 550 airlines and 1,000,000 hotels throughout the world. Whether you’re taking a break with the entire family or embarking on a solo adventure, planning a trip to Panama is better with a deal.
Where should I stay in Panama?
If you’d like to check out popular attractions such as Metropolitan Cathedral of Panama and Miraflores Locks, make sure you visit Panama City. Stay for a while to fully delve into this buzzing city.
What are the top hotels in Panama?
Hotel Riu Plaza Panama and Novotel Panama City know how to make their guests feel at home in Panama City. If your travel plans also include Bocas del Toro, look up Playa Tortuga Hotel Beach And Resort and Selina Bocas del Toro. Both are very popular with travelers.
When is the best time of year to visit Panama?
You’ll need to consider your priorities to find the right answer. Typically, you’ll land the best deals in , while is when hotel rates generally rise. Panama is at its busiest in . If you’re in the mood for a more relaxed vacation, would be a better time to pack your bags.
How far in advance should I book my Panama vacation?
It depends on the air carrier, but you can usually look up international airfares on Expedia up to a year in advance. While it’s a good idea to book ahead of time, lucky customers will sometimes find a cheaper seat only weeks before departure dates.
What does an Expedia Panama travel package include?
That depends on you. You can pick from a variety of Panama packages, such as a rental car, hotel and flight. You can also book a flight with a hotel, or a rental car with a flight. Once you’ve made your booking, you can add on the fun stuff like activities and tours. Whatever your ideal Panama vacation looks like, get set to save!
What should I know before booking a Panama travel package?
A travel package can be easier on the credit card than separately booking everything you need for your escape. For example, bundle your hotels, flights and rental cars and save a pretty penny. Whatever type of vacation you have in mind, there’s sure to be a package that suits your budget.
Does Expedia offer Book Now, Pay Later Panama vacation packages?
Expedia has partnered with online lender Affirm to help minimize any financial stress to do with your trip. This may be especially useful if your reason for travel arose unexpectedly. Book Now, Pay Later and split the cost of your hotel and activities vacation package over several payments.
Can I choose my airline with a Panama Expedia vacation package?
Yes, you sure can. Expedia has access to more than 550 partner airlines across the globe, so go with the carrier that matches your budget and traveling style.