Matthews Vacations from $302

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The Latest Matthews vacation packages

Price found within the past 48 hours. Click for updated prices.
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
6.8/10 (107 reviews)
Nice place would recommend Mary Jane’s if you’re looking for good food

Reviewed on Jun 11, 2025

Rockwood Inn

Rockwood Inn

2 out of 5
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
10/10 Exceptional! (12 reviews)
The property seemed to run on its own. We never saw the staff, except for one brief meeting of the owner. The Inn is beautiful and well maintained. We were quite comfortable.

Reviewed on May 28, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
8.8/10 Excellent! (576 reviews)
Love the outdoor patio and the inside living room area for people to come visit you at the hotel

Reviewed on Jun 24, 2025

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
8.4/10 Very Good! (866 reviews)
Clean and great for a quick stop or few days. Breakfast options were pretty limited even by 7:30 so go early if you plan on using that.

Reviewed on Jun 27, 2025

Quality Inn

Quality Inn

2.5 out of 5
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
7/10 Good! (596 reviews)
Great room, great experience

Reviewed on May 27, 2025

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Matthews Hotel Deals

Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $101 total per night from Jul 6 to Jul 7
$101 total
Jul 6 - Jul 7
Total includes taxes and fees
8.2/10 Very Good! (1,003 reviews)
"Friendly"

Reviewed on Jun 23, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Jul 3 to Jul 4
$103 total
Jul 3 - Jul 4
Total includes taxes and fees
9.4/10 Exceptional! (1,003 reviews)
"Nice atmosphere"

Reviewed on Jun 27, 2025

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Jul 6 to Jul 7
$92 total
Jul 6 - Jul 7
Total includes taxes and fees
7.2/10 Good! (1,001 reviews)
"This property is updated, fresh paint in the halls and alot of work has gone into this location. The bed is comfortable and there are plenty of pillows (4)."

Reviewed on Jun 21, 2025

Days Inn and Suites by Wyndham Sikeston
See all 36 properties in Matthews
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Matthews Vacation Packages

Matthews Essential Information

Language
English
Currency
U.S dollars
Population
630

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Frequently asked questions

How much does a Matthews vacation package cost?
You'll find cheap prices from $302 on Expedia for your Matthews escape. However, a range of factors like the length of stay, hotel choice and season will determine how much your vacation to Matthews costs.
What are the cheapest months to go to Matthews?
If you're hoping to score a cheap Matthews vacation package, consider traveling in January, September and November. You're likely to find better prices on flights and accommodations during these months --- perfect for travelers wishing to save money.
How many days is enough for Matthews?
Usually, a handful of days is enough to visit the major attractions during your Matthews vacation. But if you want to have time to chill out or take day tours, think about extending your trip.
How to find the best Matthews package deals?
Begin your search for a Matthews package deal by entering your travel dates and destination under our "Packages" tab. Then apply some filters, like "Property type" and "Guest rating," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the ideal Matthews package deal right away, just change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Matthews escape off to a flying start.
Is it cheaper to book a Matthews vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging accommodations and flights separately. Better still, you can customize your Matthews trip to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Matthews?
If you've got your Matthews travel dates locked in, book as early as you can to bag some unbeatable deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for traveling on a whim.
Does Expedia offer Book Now, Pay Later Matthews vacation packages?
Your Matthews getaway should be a relaxing escape from your busy life, not a reason for money worries. So to allow you that extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.