Medora Vacations from $252

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The Latest Medora vacation packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

$252
per person
Oct 13 - Oct 16
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
9.2/10 Wonderful! (1,676 reviews)
Remodeled and Inviting Free EV

Remodeled and Inviting Free EV

Save 100% on your flight
$416
per person
Oct 16 - Oct 19
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
10/10 Exceptional! (1 review)
It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it

Reviewed on Aug 7, 2026

The Cheshire

The Cheshire

Save 100% on your flight
$516
per person
Sep 30 - Oct 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,006 reviews)
The Knight Center at Washington University

The Knight Center at Washington University

Save 100% on your flight
$323
per person
Oct 13 - Oct 16
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
9.4/10 Exceptional! (646 reviews)
HoteLumiere at the Arch Hotel & Casino - A Caesars Rewards Destination

HoteLumiere at the Arch Hotel & Casino - A Caesars Rewards Destination

Downtown St. Louis
Save 100% on your flight
$378
per person
Oct 16 - Oct 19
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
6.8/10 (1,013 reviews)
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Medora Hotel Deals

The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

3559 College Avenue Alton IL
Fully refundable
$104 nightly
$118 total
Sep 7 - Sep 8
Total with taxes and fees
7.8/10 Good! (792 reviews)
"The room was nice, they had workers fixing and remodeling while we were there. That was nice to see. Only issue we had with the room was some light bulbs were just gone, the water pressure was terrible, and the walk in shower bar that keeps main glass secure wasn't attached to the wall. Our biggest ..."

Reviewed on Jul 31, 2026

The Great Rivers, an Ascend Collection Hotel
Comfort Inn Alton near I-255

Comfort Inn Alton near I-255

11 Crossroads Ct Alton IL
Fully refundable
$88 nightly
$100 total
Aug 20 - Aug 21
Total with taxes and fees
7.4/10 Good! (601 reviews)
"Nice, large rooms. Breakfast was so-so."

Reviewed on Aug 11, 2026

Comfort Inn Alton near I-255
 Memorable Family experiences at The Castle of Palmyra.

Memorable Family experiences at The Castle of Palmyra.

Palmyra IL
10/10 Exceptional! (167 reviews)
"We’re very disappointed that the observatory was not open. And the Beach was in unusable do to over growth weeds and grass in the sand! Cats were very nice and had some great time by the fire pit and on the boat!"

Reviewed on Jul 26, 2026

Get rates
Memorable Family experiences at The Castle of Palmyra.
See all 37 properties in Medora
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Medora Vacation Packages

Medora Essential Information

Language
English
Currency
U.S dollars
Top Sights
Beaver Dam State Park, Jersey County Historical Society and Cheney Mansion

More vacations you might like

Frequently asked questions

How much does a Medora vacation package cost?
Offering great value package deals from $252 on Expedia, you'll be pleasantly surprised at how much a vacation to Medora costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Medora?
If you'd like to snag a cheap Medora vacation package, consider planning a trip in November, December and January. You'll generally find lower rates on flights and hotels during these months — ideal for budget-conscious travelers.
How many days is enough for Medora?
With a well-organized travel plan, you can easily visit the top Medora attractions in a few days. But if you want to explore off the beaten track or go on day tours, think about booking your Medora vacation for longer.
How to find the best Medora package deals?
Start your search for a Medora package deal by entering your destination and travel dates under our "Packages" tab. Then apply a few filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the perfect Medora package deal right away, simply change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Medora escape underway.
Is it cheaper to book a Medora vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking accommodations and flights separately. Better still, you can customize your Medora getaway to match your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Medora?
Land incredible discounts by reserving your flights early with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Medora getaway.
Does Expedia offer Book Now, Pay Later Medora vacation packages?
Jet off on your dream trip to Medora with our Book Now, Pay Later vacations. No need to save up or wait until your next paycheck — we've teamed up with online lender Affirm to offer you flexibility and choice. Our vacation packages with payment plans mean you can split the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stay on budget and snag great deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.