Medora Vacations from $487

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Medora vacation packages

Price found within the past 48 hours. Click for updated prices.
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
Edmundson
Price was $567, price is now $487 per person
$487
per person
Jan 29 - Feb 1
found 23 hours ago
Roundtrip flight included
Houston (HOU) to St. Louis (STL)
8/10 Very Good! (1,002 reviews)

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was $719, price is now $599 per person
$599
per person
Jan 29 - Feb 1
found 23 hours ago
Roundtrip flight included
Houston (HOU) to St. Louis (STL)
8.6/10 Excellent! (1,080 reviews)
Great room great stay! Would definitely recommend and visit again!

Reviewed on Nov 13, 2026

Landing Furnished Apartments - Central West End

Landing Furnished Apartments - Central West End

3.5 out of 5
Central West End
Price was $614, price is now $535 per person
$535
per person
Jan 29 - Feb 1
found 23 hours ago
Roundtrip flight included
Houston (HOU) to St. Louis (STL)
7/10 Good! (7 reviews)

Residence Inn St Louis Westport

Residence Inn St Louis Westport

3 out of 5
Westport
Price was $578, price is now $505 per person
$505
per person
Jan 29 - Feb 1
found 23 hours ago
Roundtrip flight included
Houston (HOU) to St. Louis (STL)
9.2/10 Wonderful! (430 reviews)

Sheraton Westport Plaza Hotel St. Louis

Sheraton Westport Plaza Hotel St. Louis

3.5 out of 5
Westport
Price was $720, price is now $637 per person
$637
per person
Jan 29 - Feb 1
found 23 hours ago
Roundtrip flight included
Houston (HOU) to St. Louis (STL)
8.4/10 Very Good! (880 reviews)

Don't see what you're looking for?
See all available trips from Columbus to Medora
View all trips

Medora Hotel Deals

The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

3 out of 5
3559 College Avenue Alton IL
Fully refundable
$91 nightly
The price is $104 total per night from Dec 13 to Dec 14
$104 total
Dec 13 - Dec 14
Total with taxes and fees
7.8/10 Good! (825 reviews)
"I really enjoy this hotel. It is large and spacious, the rooms are clean and updated with nice aesthetic. The Mexican restaurant attached is good. The best part is the family that owns/lives here. They gave us ice cream in the lobby just because we were up late working while they were pulling some ..."

Reviewed on Nov 12, 2026

The Great Rivers, an Ascend Collection Hotel
Best Western Plus Parkway Hotel

Best Western Plus Parkway Hotel

2.5 out of 5
1900 Homer Adams Pkwy Alton IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Nov 22 to Nov 23
$102 total
Nov 22 - Nov 23
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
"The young lady at the front desk was the main reason our stay was so pleasant."

Reviewed on Nov 2, 2026

Best Western Plus Parkway Hotel
Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG

2.5 out of 5
2008 HOMER ADAMS PARKWAY Alton IL
Fully refundable
$122 nightly
The price is $139 total per night from Nov 29 to Nov 30
$139 total
Nov 29 - Nov 30
Total with taxes and fees
9/10 Wonderful! (251 reviews)
"Great for business or pleasure."

Reviewed on Nov 11, 2026

Holiday Inn Express and Suites Alton St Louis Area by IHG
See all 37 properties in Medora
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Medora Vacation Packages

Medora Essential Information

Language
English
Currency
U.S dollars
Top Sights
Beaver Dam State Park, Jersey County Historical Society and Cheney Mansion

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Medora vacation package cost?
Offering great value package deals from $487 on Expedia, you'll be pleasantly surprised at how much a vacation to Medora costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Medora?
If you'd like to snag a cheap Medora vacation package, consider planning a trip in November, December and January. You'll generally find lower rates on flights and hotels during these months — ideal for budget-conscious travelers.
How many days is enough for Medora?
With a well-organized travel plan, you can easily visit the top Medora attractions in a few days. But if you want to explore off the beaten track or go on day tours, think about booking your Medora vacation for longer.
How to find the best Medora package deals?
Start your search for a Medora package deal by entering your destination and travel dates under our "Packages" tab. Then apply a few filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the perfect Medora package deal right away, simply change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Medora escape underway.
Is it cheaper to book a Medora vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking accommodations and flights separately. Better still, you can customize your Medora getaway to match your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Medora?
Land incredible discounts by reserving your flights early with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu Medora getaway.
Does Expedia offer Book Now, Pay Later Medora vacation packages?
Jet off on your dream trip to Medora with our Book Now, Pay Later vacations. No need to save up or wait until your next paycheck — we've teamed up with online lender Affirm to offer you flexibility and choice. Our vacation packages with payment plans mean you can split the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stay on budget and snag great deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.