A mountainous landscape with a prominent peak, a valley with a body of water, and a sunset in the background.

Mendrisio District Vacations & Trips from $1,126

Book a Hotel + Flight or Car together to unlock savings

Your Mendrisio District Vacation

When adventure calls, answer it with a customized vacation package to Mendrisio District. Wherever you're headed and whatever you have planned, get ready to immerse yourself in a destination that'll make you truly feel alive. Begin your trip to Mendrisio District by spending a few nights in Stabio, one of the most popular cities here. Whether you're traveling on a shoestring or in the lap of luxury, Expedia are here to help you organize your next dream Mendrisio District vacation.

Top destinations in Mendrisio District

The Latest Mendrisio District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 28 - Feb 3

    Kurhaus Cademario Hotel & SPA + Flight

    Cademario
    5 nights
    4.5 star property
    9.2/10 - Wonderful (868 reviews)
    Roundtrip • Boston (BOS) - Lugano (LUG)
    BOS - MXP • 1 stop MXP - BOS • 1 stop
    $1,406
    $1,126
    per traveler
    found 1 day ago
    Kurhaus Cademario Hotel & SPA
  • Feb 2 - Feb 8

    Collina d'Oro Resort & SPA + Flight

    Collina d'Oro
    5 nights
    5.0 star property
    9.2/10 - Wonderful (189 reviews)
    Roundtrip • New York (JFK) - Lugano (LUG)
    JFK - MXP • Nonstop MXP - JFK • Nonstop
    $1,640
    $1,302
    per traveler
    found 18 hours ago
    Collina d'Oro Resort & SPA
  • Jan 28 - Feb 3

    Swiss Diamond Boutique Hotel La Romantica + Flight

    Melide
    5 nights
    5.0 star property
    9.8/10 - Exceptional (66 reviews)
    "The best!!!"
    Reviewed October 30, 2026
    Roundtrip • Boston (BOS) - Lugano (LUG)
    BOS - MXP • 1 stop MXP - BOS • 1 stop
    $1,861
    $1,508
    per traveler
    found 1 day ago
    Swiss Diamond Boutique Hotel La Romantica
  • Jan 28 - Feb 3

    Swiss Diamond Hotel & SPA + Flight

    Vico Morcote
    5 nights
    5.0 star property
    9.0/10 - Wonderful (471 reviews)
    Roundtrip • Boston (BOS) - Lugano (LUG)
    BOS - MXP • 1 stop MXP - BOS • 1 stop
    $1,555
    $1,295
    per traveler
    found 1 day ago
    Swiss Diamond Hotel & SPA
  • Dec 28 - Jan 3

    Hotel De La Paix + Flight

    Loreto
    5 nights
    3.5 star property
    8.8/10 - Excellent (658 reviews)
    "I enjoyed my stay. Staff were friendly and helpful, room was clean and comfortable, breakfast was excellent, a good restaurant attached to the hotel, a short walk to the lake and funicular San Salvatore and transit nearby. I would stay again."
    Reviewed November 4, 2026
    Roundtrip • Boston (BOS) - Lugano (LUG)
    BOS - MXP • 1 stop MXP - BOS • 1 stop
    $2,256
    $1,888
    per traveler
    found 1 day ago
    Hotel De La Paix

Discover the most popular places to visit in Mendrisio District

What to do in Mendrisio District

Mendrisio District Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.