Find hotels in Mesadha from $88

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Dec 27 - Dec 28
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Our top choices for Mesadha hotels

Front of property
Philippos Xenia Hotel

Philippos Xenia Hotel

Philippos Xenia Hotel
4.0 star property
Serres
8.4 out of 10, Very Good, (25)
"Good value parking and excellent restaurant, delicious food"
United Kingdom
Jennifer
Philippos Xenia Hotel
Standard Room | 1 bedroom, soundproofing, WiFi, bed sheets
Acropol

Acropol

Acropol
4.0 star property
Serres
8.4 out of 10, Very Good, (15)
"Hotel was rated as a 4*. As i m an experienced traveler, i was expecting more of this property. They must have received the 4* when they first opened due to supposed facilities they had. Room was totally outdated, the pavement partially cleaned, there was issues with the light so that some lights turned on in the middle of the night, minibar was not existing, the minibar fridge was not working properly, the safe was not working, the bathroom tub - jacuzzi was not working either. We went for...
United States
Vittoria
$75 nightly
The price is $88
Jan 11 - Jan 12, 2026
Total with taxes and fees
Acropol
Outdoor pool, open 11:00 AM to 8:30 PM, pool umbrellas, sun loungers
Agnatio Hotel Spa

Agnatio Hotel Spa

Agnatio Hotel Spa
3.0 star property
Sintiki
9.8 out of 10, Exceptional, (8)
"Nous avons passé un très agréable séjour. Le personnel a été d'une très grande gentillesse avec nous et tout s'est bien passé."
France
serge
$85 nightly
The price is $99
Jan 6 - Jan 7, 2026
Total with taxes and fees
Agnatio Hotel Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesadha Hotel Reviews

Acropol

Acropol

10/10 Excellent
"Comfortable spacious room. "
Norman 1-night trip
Posted 2 weeks ago
Acropol

More cheap stays in Mesadha

Metropolis

Metropolis

Dion. Solomou Str. - Emporiou Sq., 49 Serres Central Macedonia
Get rates
8/10 Very Good! (8 reviews)

Frequently asked questions

Where is the best place to stay in Mesadha?
Philippos Xenia Hotel, located 13.3 mi (21.4 km) from the heart of Mesadha, is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Agnatio Hotel Spa and Acropol. See all available top hotels, or vacation rentals in Mesadha.
What are some of the best vacation home rentals that Mesadha has to offer?
Villa Acropolis Serres Next to Center (Parking): This vacation home rental outside of Mesadha is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a coffee maker, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Mesadha.
If I need to cancel my hotel reservation in Mesadha, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesadha.
Where can I learn more about changing or cancelling my trip to Mesadha?
For additional details about rescheduling or cancelling your trip to Mesadha, click here.
What's the best hotel for staying near Macedonia Airport (SKG)?
Hyatt Regency Thessaloniki is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.1 mi (1.8 km) from Macedonia Airport. Other options near the airport are Athina Airport Hotel and Hotel Nikopolis.
What is staying in Mesadha like?
Travelers to Mesadha will find plenty to explore and enjoy. There are 15 hotels and other accommodations in the surrounding area. Find out more about Mesadha.
What should I do while I'm visiting Mesadha?
Places to visit in the wider area include Cave of Alistrati, Roupel Bunker, and Sarakatsani Folklore Museum. You'll also find Irakleia Central Square and Archeological Museum of Mpezesteni-Serres in the area. Check out what more to see and do in Expedia's Mesadha guide.
What's the seasonal weather like in Mesadha?
The hottest months are usually August and July with an average temp of 78°F, while the coldest months are January and February with an average of 44°F. Average annual precipitation for Mesadha is 29 inches.