
Mesotopos Vacations from $530
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Your Mesotopos Vacation
History, cuisine, art and more … It's all waiting for you with a Mesotopos vacation package. And with the ability to customize your city getaway, you know it'll be one that's tough to forget. Every trip to Mesotopos needs a well-thought-out itinerary. Fill yours with major attractions such as Naturist Beach, Ágios Panteleímon and Podarás. Browse Expedia's wide range of travel options and start planning your ultimate vacation to Mesotopos now.
The Latest Mesotopos vacation packages
Price found within the past 48 hours. Click for updated prices.


Mythical Coast Wellness Retreat
Price was $811, price is now $649 per person
$649
per person
Oct 16 - Oct 21
found 2 hours ago
Roundtrip non-stop flight included
Berlin (BER) to Mytilene (MJT)
8.6/10 Excellent! (42 reviews)
Great property with lovely views and friendly staff. Only issue is that the upper floors of some buildings are not handicapped accessible and you will have to carry luggage’s up the stairs. To avoid stay on one of the main buildings
Reviewed on Aug 2, 2024


The Loriet
Price was $673, price is now $549 per person
$549
per person
Oct 16 - Oct 21
found 2 hours ago
Roundtrip non-stop flight included
Berlin (BER) to Mytilene (MJT)
8.4/10 Very Good! (70 reviews)
Perfect hotel! Very authentic and beautiful. The only negative I would give is the lighting and the steps in the room.
Reviewed on Aug 8, 2025

Theofilos Paradise Boutique Hotel
Price was $798, price is now $725 per person
$725
per person
Oct 16 - Oct 21
found 2 hours ago
Roundtrip non-stop flight included
Berlin (BER) to Mytilene (MJT)
9.6/10 Exceptional! (152 reviews)
For a small island seperated from the mainland, this hotel exceeded my expectations. Clean, spacious rooms and the new, modern building made the difference. No mold or moldy smell in the rooms. Central AC cooled the rooms very quickly when needed. The bed was really comfortable. The hotel is situated in the middle of shopping and dining district, with many dining options nearby. Yet, when we closed the windows, we didn’t hear much noise. The cafes and bars remained open and bustling until 1-2am (summertime, I don’t know about winter). Friendly and helpful staff was also a plus. Breakfast wasn’t special, but good. I always appreciate eggs in the morning as they keep me full for longer. Both morning had a selection of eggs and cheese, olives, a few kinds of jams, some tomatoes and cucumbers. They also had local pastries for breakfast, and of course, yoghurt.
Reviewed on Aug 13, 2025
Mesotopos Hotel Deals

Delfinia Hotel & Bungalows
Molyvos, Mythimna, North Aegean Islands, Lesvos
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $116 total per night from Sep 10 to Sep 11
$116 total
Sep 10 - Sep 11
Total with taxes and fees

Aeolian Village Beach Resort
Aeolian Village, Skala Eresos, Lesvos, Lesvos

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.