Mesotopos Vacations from $1,252

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Your Mesotopos Vacation

History, cuisine, art and more … It's all waiting for you with a Mesotopos vacation package. And with the ability to customize your city getaway, you know it'll be one that's tough to forget. Every trip to Mesotopos needs a well-thought-out itinerary. Fill yours with major attractions such as Naturist Beach, Ágios Panteleímon and Podarás. Browse Expedia's wide range of travel options and start planning your ultimate vacation to Mesotopos now.

The Latest Mesotopos vacation packages

Price found within the past 48 hours. Click for updated prices.
Aeolian Village Beach Resort

Aeolian Village Beach Resort

4 out of 5
Price was $1,416, price is now $1,252 per person
$1,252
per person
Aug 31 - Sep 4
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Mytilene (MJT)
9/10 Wonderful! (25 reviews)
Hotel has the Best sea/beach in the area. Turnover doesnt meet the expectation. Dinner was good, breakfast product quality was poor. 1.5 hour drive from the ferry. But overall it was a nice stay for us

Reviewed on Jul 27, 2025

Hotel Delfinia

Hotel Delfinia

3 out of 5
Price was $1,640, price is now $1,361 per person
$1,361
per person
Jul 13 - Jul 18
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Mytilene (MJT)
7.6/10 Good! (115 reviews)
Clean rooms. Nice property right on the beach. Only downside was the pool closed too early.

Reviewed on Sep 17, 2025

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Mesotopos Hotel Deals

Clara Hotel

Clara Hotel

3 out of 5
Avlaki Petras Lesvos Lesvos Island
7.8/10 Good! (17 reviews)
Great hotel to stay in Petra! A++
"Great place to stay in Petra, great service, great location, great experience!"

Reviewed on Aug 16, 2024

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Clara Hotel
Aeolian Village Beach Resort

Aeolian Village Beach Resort

4 out of 5
Aeolian Village, Skala Eresos Lesvos Lesvos
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $119 total per night from Jun 13 to Jun 14
$119 total
Jun 13 - Jun 14
Total with taxes and fees
9/10 Wonderful! (25 reviews)
"A lovely place to stay! The hotel rooms were super modern, aircon worked well, small fridge, hairdryer, shower was good, bed was comfy, balcony was nice! The staff were amazing too, masseuse did an excellent massage for my partners back! Pool was really nice, always a life guard on duty, plenty of ..."

Reviewed on May 25, 2026

Aeolian Village Beach Resort
Aegeon Hotel

Aegeon Hotel

3 out of 5
Skala Kallonis Lesvos
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $67 total per night from Jun 17 to Jun 18
$67 total
Jun 17 - Jun 18
Total with taxes and fees
8.8/10 Excellent! (28 reviews)
"Nice Staff and bartender. Good concept in the middle of rural. Next to seaside. Best value for money."

Reviewed on Sep 6, 2024

Aegeon Hotel
See all 137 properties in Mesotopos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mesotopos Vacation Packages

Mesotopos Essential Information

Language
Greek
Currency
Euros
Local Welcome
Ya su
Local Goodbye
Yiá sou
Population
770
Top Sights
Skala Kallonis Beach, Natural History Museum of the Lesvos Petrified Forest and Naturist Beach

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Frequently asked questions

How much does a Mesotopos vacation package cost?
Offering excellent value package deals from $1,252 on Expedia, you'll be pleasantly surprised at how much a vacation to Mesotopos costs! Expedia's packages make travel planning easier and your savings go further.
What are the cheapest months to go to Mesotopos?
You can usually find reduced prices and greater availability in September, November and December. Browse our cheap Mesotopos vacation packages and you could score some excellent off-season deals.
How many days is enough for Mesotopos?
With a well-organized itinerary, you can easily visit the main Mesotopos sights in a few days. But if you'd like to discover hidden spots or go on day tours, consider booking your Mesotopos vacation for longer.
How to find the best Mesotopos package deals?
Landing a cheap Mesotopos package deal is a breeze with Expedia. Once you've entered your travel dates and destination under our "Packages" tab, set your budget range, apply a couple of filters and browse what's available. You can tweak your search by "Area," "Amenities," "Property type" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Mesotopos package deals. Want a simple trick to score the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are usually lower.
Is it cheaper to book a Mesotopos vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking hotels and flights individually. Better still, you can customize your Mesotopos trip to fit your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Mesotopos?
If you've got your Mesotopos travel dates finalized, book early to grab some outstanding deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are ideal for setting off on a whim.
Does Expedia offer Book Now, Pay Later Mesotopos vacation packages?
If you're like us, you love traveling the world but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Mesotopos trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.