Mezzojuso Vacations from $1,549

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Mezzojuso Vacation

Our Mezzojuso vacation packages offer countless opportunities to discover new sights, sounds and smells. And with all of the travel arrangements taken care of, you can let go and enjoy your city getaway without a care in the world. Royal Palace of Ficuzza is one of the leading attractions to include on your sightseeing agenda during a trip to Mezzojuso. A few clicks is all it takes to put together the ultimate Mezzojuso vacation on Expedia.

The Latest Mezzojuso vacation packages

Price found within the past 48 hours. Click for updated prices.
Ambasciatori Hotel

Ambasciatori Hotel

4 out of 5
Palermo Historical Center
Price was $1,801, price is now $1,549 per person
$1,549
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Palermo (PMO)
8.4/10 Very Good! (1,000 reviews)
Ac work well. Spacious room

Reviewed on Apr 26, 2026

The Signature Level at Grand Palladium Sicilia Resort & Spa

The Signature Level at Grand Palladium Sicilia Resort & Spa

5 out of 5
Price was $3,226, price is now $2,449 per person
$2,449
per person
Jul 18 - Jul 24
found 1 hour ago
Roundtrip non-stop flight included
Boston (BOS) to Palermo (PMO)
9.4/10 Exceptional! (17 reviews)
The drinking glasses were dirty most of the time. That was disappointing. The staff were lovely and pleasant. Dinner timings and options were limited. We were signature level and would have expected options for sea view, but those seemed to only be for the main building Food was okay.

Reviewed on Oct 7, 2025

Grand Palladium Sicilia Resort & Spa

Grand Palladium Sicilia Resort & Spa

5 out of 5
Price was $2,846, price is now $2,210 per person
$2,210
per person
Jul 18 - Jul 24
found 1 hour ago
Roundtrip non-stop flight included
Boston (BOS) to Palermo (PMO)
8.8/10 Excellent! (148 reviews)
Amazing time! I honestly loved the bungalows we stayed in, felt like a high end experience even though the signature stay is a better experience but we truly loved our room and the staff was so nice and the buffet was amazing didn't really need to experience the other restaurants and the bar in the lobby was amazing

Reviewed on May 7, 2026

Hotiday Apartments Cefalù

Hotiday Apartments Cefalù

4 out of 5
Price was $2,589, price is now $2,164 per person
$2,164
per person
Jul 12 - Jul 18
found 1 day ago
Roundtrip flight included
Akron (CAK) to Palermo (PMO)
9/10 Wonderful! (2 reviews)
The property was a good size and had a washing machine and spa. It was well presented. It was a little out of Cefalu and I would have preferred something a little closer or alternatively I stayed in the actual resort at another time and enjoyed the location more. A major advantage of the apartment is that it comes with access to resort areas and the beach is wonderful.

Reviewed on Oct 9, 2025

MClub Cala Regina

MClub Cala Regina

4 out of 5
Price was $2,411, price is now $2,036 per person
$2,036
per person
Jun 14 - Jun 20
found 2 hours ago
Roundtrip non-stop flight included
New York (NYC) to Palermo (PMO)
8/10 Very Good! (16 reviews)
The property was dated and room smelled of smoke.

Reviewed on Sep 9, 2021

Don't see what you're looking for?
See all available trips from Columbus to Mezzojuso
View all trips

Mezzojuso Hotel Deals

Hotel Politeama

Hotel Politeama

4 out of 5
Piazza Ruggiero Settimo,15 Palermo PA
$177 nightly
The price is $206 total per night from Jun 7 to Jun 8
$206 total
Jun 7 - Jun 8
Total with taxes and fees
9.4/10 Exceptional! (548 reviews)
I had a great stay at Hotel Politeama in Palermo. The location is unbeatable—right in the heart of the city, making it easy to explore shops, restaurants, and major attractions. The rooms were clean, comfortable, and well-maintained, and the staff was friendly and helpful throughout my stay. Breakfast ...

Reviewed on May 11, 2026

Hotel Politeama
Grand Hotel Wagner

Grand Hotel Wagner

5 out of 5
Via R. Wagner, 2 Palermo PA
Fully refundableReserve now, pay when you stay
$225 nightly
The price is $260 total per night from Jun 7 to Jun 8
$260 total
Jun 7 - Jun 8
Total with taxes and fees
9/10 Wonderful! (834 reviews)
The hotel is nice and the rooms have high ceilings, but it needs a complete refurbishment. No view at all. 2 small windows opening to small row of backyard. The staff were nice. The bed was good and comfortable, and the breakfast was acceptable.

Reviewed on May 10, 2026

Grand Hotel Wagner
NH Palermo

NH Palermo

4 out of 5
Foro Italico Palermo PA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $174 total per night from Jun 7 to Jun 8
$174 total
Jun 7 - Jun 8
Total with taxes and fees
8.2/10 Very Good! (1,004 reviews)
Great breakfast buffet

Reviewed on May 10, 2026

NH Palermo
See all 3,264 properties in Mezzojuso
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mezzojuso Vacation Packages

Mezzojuso Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Punta Raisi Airport (PMO)
Population
2,600
Top Sights
C.I.D.M.A. International Documentary Center of Mafia and the No Mafia Movement, Cascata delle Due Rocche and Caccamo Castle

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Mezzojuso vacation package cost?
You can snap up a vacation package to this destination from $1,549 on Expedia. But how much your vacation to Mezzojuso costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Mezzojuso?
If you'd like to snag a cheap Mezzojuso vacation package, consider visiting in November, December and January. You'll generally find better prices on airfares and hotels during these quieter months — ideal for a budget-friendly break.
How many days is enough for Mezzojuso?
The ideal length for your Mezzojuso vacation depends on what you'd like to do. Generally, a few days to a week will give you enough time to tick off all the major attractions and explore some hidden treasures along the way.
How to find the best Mezzojuso package deals?
Bagging a cheap Mezzojuso package deal is a cinch with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your budget range, apply a couple of filters and browse what's available. You can tailor your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most pocket-friendly Mezzojuso package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Mezzojuso vacation as a package?
You can enjoy significant savings on your next Mezzojuso getaway by booking a tailored vacation package. Click on the "Package" heading, then select your destination and travel dates to browse some great flight and hotel prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Mezzojuso?
If you've got your Mezzojuso travel dates finalized, book as soon as you can to score some outstanding deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for traveling on a whim.
Does Expedia offer Book Now, Pay Later Mezzojuso vacation packages?
Set off on your ideal getaway to Mezzojuso with help from Expedia's Book Now, Pay Later vacations. There's no need to save like crazy or hold off until your next paycheck — we've partnered with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans allow you to spread the cost over 3, 6 or 12 months. With no hidden or late payment fees, it's easy to stay on budget and snap up cheap deals before they sell out.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.