
Midtown Vacations from $620
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Midtown Vacation
Lock in a vacation package to Midtown and experience everything this busy neighborhood has to offer. Known for its shopping, cafes and nightlife, your next epic adventure can be found right here. Start your trip to Midtown by visiting nearby attractions such as Alamo, Alamodome and San Antonio Zoo and Aquarium. Stop dreaming and start doing. When you're ready to lock in your dream vacation to Midtown, Expedia is here to help.
The Latest Midtown Vacation Packages

O´Brien Historic Hotel
Reviewed on May 9, 2026


Signia by Hilton La Cantera Resort & Spa
Reviewed on May 9, 2026

Hyatt Regency Hill Country Resort and Villas
Reviewed on Apr 28, 2026
Where to stay in Midtown

Downtown San Antonio
Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.
Midtown Hotel Deals

Riverwalk Plaza
The stay was suitable and felt safe. The staff was courteous. They obviously didn’t care about people smoking marijuana in the rooms because you could hardly walk down the hallway for the stitch. Definitely needs an update done to the facility. Three star property.
Reviewed on May 10, 2026

Drury Plaza Hotel San Antonio Riverwalk
Roof top pool is great. Direct access to Riverwalk is great for mobility challenged so as to avoid using stairs. Valet parking is convenient but expensive. Our room had a lot of street noise so good to use ear plugs which I did. Check room location for street noise if you are sensitive to that.
Reviewed on May 10, 2026

Menger Hotel
Beautiful pool and lobby
Reviewed on May 10, 2026
Discover the most popular places to visit in Midtown

San Antonio Zoo and Aquarium
There are nearly 800 wild and wonderful species at the zoo in the center of Brackenridge Park, not far from the city center.

Trinity University
Enjoy the collegiate vibe at Trinity University during your stay in San Antonio. Experience the entertainment choices and lively festivals in this walkable area.

Brackenridge Park
Brackenridge Park is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Experience the great live music and acclaimed theater scene in this walkable area.
Things to do


























