Mosel Wine Region Vacations from $800

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Your Mosel Wine Region Vacation

Reserve a vacation package to Mosel Wine Region and go wherever your adventurous soul takes you. This destination has plenty to offer, including its nature, history, festivals, and so much more. Start your trip to Mosel Wine Region with some time in Trier visiting popular sights like Trier Roman Amphitheatre and Trier Christmas Market. Koblenz is another top city that draws crowds from far and wide. Deutsches Eck and Ehrenbreitstein Fortress are two of the leading places to see in this destination. Expedia has hotels, flights, car rentals and more to help you curate your very own tailored Mosel Wine Region vacation today.

The Latest Mosel Wine Region vacation packages

Price found within the past 48 hours. Click for updated prices.
FAVORITE Parkhotel I Spa – Business – Fine Dining

FAVORITE Parkhotel I Spa – Business – Fine Dining

Oberstadt
$800
per person
Dec 12 - Dec 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Frankfurt (FRA)
8.6/10 Excellent! (288 reviews)
The hotel is very well equipped and the staff were courteous and helpful. My personal criticism is the rooms are poorly soundproofed and having the Gym on the top floor is not the best option. I could hear every dropped dumbbell. Such a shame as the location is great.

Reviewed on Aug 13, 2026

Villa Westend Hotel an der Messe

Villa Westend Hotel an der Messe

Westend-Süd
$921
per person
Dec 5 - Dec 10
found 1 day ago
Roundtrip non-stop flight included
Seattle (SEA) to Frankfurt (FRA)
8.2/10 Very Good! (199 reviews)
Very nice hotel . Room was spacious , breakfast was delicious and staff very attentive . Only a short walk from main station and old town

Reviewed on Aug 23, 2026

Villahotel Rheinblick

Villahotel Rheinblick

Rodenkirchen
$1,339
per person
Dec 4 - Dec 8
found 1 day ago
Roundtrip non-stop flight included
Chicago (ORD) to Cologne (CGN)
9.2/10 Wonderful! (157 reviews)
Very clean and accommodating. We arrived earlier then our check in. The staff allowed us to store our luggage.

Reviewed on Sep 1, 2026

Hotel am Augustinerplatz

Hotel am Augustinerplatz

Old Town Cologne
$1,506
per person
Dec 3 - Dec 8
found 1 day ago
Roundtrip non-stop flight included
Chicago (ORD) to Cologne (CGN)
8/10 Very Good! (515 reviews)
Messehotel Köln-Deutz

Messehotel Köln-Deutz

Innenstadt
$1,158
per person
Nov 11 - Nov 17
found 1 day ago
Roundtrip flight included
Madison (MSN) to Cologne (CGN)
8.2/10 Very Good! (95 reviews)
This is a lovely quiet hotel within walking distance of the busy central Cologne. The staff couldn't be more helpful, even ensuring we had a room on arrival 4 hours before the official check in time. We were even offered refreshments while we waited. The room is clean and the towels etc changed every day. Supermarkets, cafes etc within easy walking distance. Id definitely recommend if you want the peace away from the hustle and bustle of central Cologne.

Reviewed on Dec 8, 2025

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Where to stay in Mosel Wine Region

Find the best Mosel Wine Region areas and neighborhoods for the activities you enjoy most. Learn more about Mosel Wine Region
A large classical building with symmetrical architecture, a well-maintained garden with hedges and flower beds, and a clear sky.

Altstadt Koblenz

1 out of top 10 points of interest in this area

You'll enjoy the museums and riverfront in Altstadt Koblenz. You might want to make time for a stop at Koblenz Town Hall or Forum Mittelrhein.

A historic stone building with arched windows and a dome.

Altstadt Trier

2 out of top 10 points of interest in this area

Altstadt Trier is noteworthy for its historic sites, and you can make a stop at top attractions like Trier Christmas Market and Karl Marx House.

A historic square with a prominent clock tower, traditional buildings, and a cobblestone street.

Mitte

Mitte is noteworthy for its historic sites, and you can make a stop at top attractions like Trier Christmas Market and Karl Marx House.

A stone archway with a view of a river and a town below.

Historic Downtown

The restaurants and wineries are a few reasons travelers visit Historic Downtown. Want to see more of the surrounding area? Landshut Castle and Winery Dr. Loosen are a few top sights nearby.

A nighttime cityscape with a river reflecting lights, a prominent castle-like building, and a bridge.

Mitte

Unique features of Mitte include the river views and bars. Make a stop by Rhein Mosel Halle Congress Center or Rhine while you're exploring the area.

Stay near popular Mosel Wine Region attractions

A castle on a hill with a cobblestone path leading up to it.

Burg Eltz

9.0/10 (262 reviews)
You can learn about the history of Wierschem when you stop by Burg Eltz. Wander the riverfront in this quaint area.
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A river with boats, a castle on a hill, and a church with a tall spire.

Moselle Promenade

9.0/10 (473 reviews)
Explore the great outdoors at Moselle Promenade, a lovely green space in Cochem. While you're in the area, stroll along the riverfront.
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A river with a bridge, a statue, and a waterfront promenade with flags.

Deutsches Eck

9.0/10 (491 reviews)
Watch the boats at the meeting of two grand rivers and inspect the replica of a momentous sculpture at the German Corner.
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A river with boats, a castle on a hill, and a church with a spire.

Reichsburg Cochem

9.0/10 (379 reviews)
Reichsburg Cochem is just one of the places to see in Cochem, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the riverfront.
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A historic stone building with arched windows and a dome.

Porta Nigra

9.2/10 (803 reviews)
Glimpse the ancient world when you explore the interior chambers of this Roman relic, the largest surviving city gate north of the Alps and a UNESCO World Heritage Site.
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A historic church with two towers and a large clock.

Trier Cathedral

9.4/10 (525 reviews)
Study the majestic design of this fortress-like structure, which is the largest church in the city and one of Germany’s oldest cathedrals.
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A historic castle on a hill overlooking a calm river, with buildings and a bridge in the foreground.

Ehrenbreitstein Fortress

8.8/10 (295 reviews)
Take the cable car on a scenic journey to a mountaintop to see one of the largest preserved forts in Europe.
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Vulkaneifel Thermal Spa

8.8/10 (53 reviews)
Explore the great outdoors at Vulkaneifel Thermal Spa, a lovely green space in Bad Bertrich. While you're in the area, stroll along the riverfront.
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Mosel Wine Region Hotel Deals

bestprice Hotel Koblenz

bestprice Hotel Koblenz

Bahnhofpl. 1 Koblenz RP
Fully refundableReserve now, pay when you stay
$64 nightly
$68 total
Oct 4 - Oct 5
Total with taxes and fees
8/10 Very Good! (91 reviews)
"Lacking in soft furnishings which makes the room and dining room feel less cosy but this is only an opinion. It was still excellent one night."

Reviewed on Sep 16, 2026

bestprice Hotel Koblenz
Schloss Lieser, Autograph Collection

Schloss Lieser, Autograph Collection

Moeselstrasse 33 Lieser
$184 nightly
$197 total
Oct 18 - Oct 19
Total with taxes and fees
9/10 Wonderful! (235 reviews)
"For such an expensive hotel, surprised beds were not made up properly every day. Cushions were left on the floor. Breakfast is very expensive and ought to be included when you are paying 300 euros a night. Fantastic building though and wonderful location."

Reviewed on Sep 14, 2026

Schloss Lieser, Autograph Collection
Premier Inn Koblenz City

Premier Inn Koblenz City

Clemensstrasse 32 Koblenz
Fully refundableReserve now, pay when you stay
$75 nightly
$80 total
Oct 18 - Oct 19
Total with taxes and fees
8.4/10 Very Good! (46 reviews)
"The hotel was located in the center of Koblenz with the tourist information center across the street which made it very helpful when we had questions."

Reviewed on Sep 12, 2026

Premier Inn Koblenz City
See all 3,315 properties in Mosel Wine Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mosel Wine Region Vacation Packages

Mosel Wine Region Essential Information

Language
German
Currency
Euros
Local Welcome
Guten Tag
Local Goodbye
Tschüss
Closest Airport
Frankfurt Intl. Airport (FRA)

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