Mosel Wine Region Vacations from $299

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Your Mosel Wine Region Vacation

Reserve a vacation package to Mosel Wine Region and go wherever your adventurous soul takes you. This destination has plenty to offer, including its nature, history, festivals, and so much more. Start your trip to Mosel Wine Region with some time in Trier visiting popular sights like Trier Roman Amphitheatre and Trier Christmas Market. Koblenz is another top city that draws crowds from far and wide. Deutsches Eck and Ehrenbreitstein Fortress are two of the leading places to see in this destination. Expedia has hotels, flights, car rentals and more to help you curate your very own tailored Mosel Wine Region vacation today.

The Latest Mosel Wine Region vacation packages

Price found within the past 48 hours. Click for updated prices.
The Central City - Luxury ApartHotel

The Central City - Luxury ApartHotel

Bonnevoie
Save 100% on your flight
$299
per person
Oct 10 - Oct 12
found 1 day ago
Roundtrip flight included
London (LON) to Luxembourg (LUX)
9.4/10 Exceptional! (76 reviews)
Short overnight stay, close to Tran station for travel.

Reviewed on Aug 31, 2026

The Queen Luxury Apartments Villa Vinicia

The Queen Luxury Apartments Villa Vinicia

Save 100% on your flight
$415
per person
Oct 1 - Oct 4
found 1 day ago
Roundtrip flight included
London (LON) to Luxembourg (LUX)
8.6/10 Excellent! (40 reviews)
The apartment was spotless and so spacious. The bed and the sofa bed were both really comfy. The bathroom had a spa bath which was a nice surprise. The kitchen had everything we needed snd the washing machine was a handy bonus. The location was great and really easy to walk into the city or catch a tram. We drove and could park the car outside for 30mins to unpack before taking it to a nearby car park. Overall a great stay, thank you.

Reviewed on Aug 21, 2026

Hotel du Commerce

Hotel du Commerce

Save 100% on your flight
$338
per person
Oct 1 - Oct 4
found 1 day ago
Roundtrip flight included
London (LON) to Luxembourg (LUX)
8.2/10 Very Good! (111 reviews)
The hotel is centrally located and well managed. Rooms are spotless. It was a great place to spend two days en route to Vianden.

Reviewed on Aug 10, 2026

The Seven Hotel

The Seven Hotel

Save 100% on your flight
$329
per person
Oct 1 - Oct 4
found 1 day ago
Roundtrip flight included
London (LON) to Luxembourg (LUX)
8.4/10 Very Good! (101 reviews)
A most positive surprise on our travels: Very helpful and professional staff, hotel smart and functional with a most inspiring restaurant. We loved it all.

Reviewed on Sep 24, 2025

INNSiDE by Meliá Luxembourg

INNSiDE by Meliá Luxembourg

Gasperich
Save 100% on your flight
$355
per person
Oct 1 - Oct 4
found 1 day ago
Roundtrip flight included
London (LON) to Luxembourg (LUX)
9.2/10 Wonderful! (388 reviews)
It wasn’t clear to me how far from the city it was. Was not happy with the hotel overall

Reviewed on Aug 5, 2026

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Where to stay in Mosel Wine Region

Find the best Mosel Wine Region areas and neighborhoods for the activities you enjoy most. Learn more about Mosel Wine Region
A large classical building with symmetrical architecture, a well-maintained garden with hedges and flower beds, and a clear sky.

Altstadt Koblenz

2 out of top 10 points of interest in this area

You'll enjoy the museums and riverfront in Altstadt Koblenz. You might want to make time for a stop at Koblenz Town Hall or Forum Mittelrhein.

A historic square with a prominent clock tower, traditional buildings, and a cobblestone street.

Mitte

2 out of top 10 points of interest in this area

Mitte is noteworthy for its historic sites, and you can make a stop at top attractions like Trier Christmas Market and Karl Marx House.

A historic stone building with arched windows and a dome.

Altstadt Trier

Altstadt Trier is noteworthy for its historic sites, and you can make a stop at top attractions like Trier Christmas Market and Karl Marx House.

A nighttime cityscape with a river reflecting lights, a prominent castle-like building, and a bridge.

Mitte

Unique features of Mitte include the river views and bars. Make a stop by Rhein Mosel Halle Congress Center or Rhine while you're exploring the area.

Bernkastel-Kues is a charming town located on the banks of the Moselle River in Germany. It is famous for its  ruins of Landshut Castle overlooking the town.

Historic Downtown

The restaurants and wineries are a few reasons travelers visit Historic Downtown. Want to see more of the surrounding area? Landshut Castle and Winery Dr. Loosen are a few top sights nearby.

Stay near popular Mosel Wine Region attractions

A river with a bridge, a statue, and a waterfront promenade with flags.

Deutsches Eck

9.0/10 (491 reviews)
Watch the boats at the meeting of two grand rivers and inspect the replica of a momentous sculpture at the German Corner.
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A castle on a hill with a cobblestone path leading up to it.

Burg Eltz

9.0/10 (262 reviews)
You can learn about the history of Wierschem when you stop by Burg Eltz. Wander the riverfront in this quaint area.
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A river with boats, a castle on a hill, and a church with a tall spire.

Moselle Promenade

9.0/10 (473 reviews)
Explore the great outdoors at Moselle Promenade, a lovely green space in Cochem. While you're in the area, stroll along the riverfront.
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A river with boats, a castle on a hill, and a church with a spire.

Reichsburg Cochem

9.0/10 (379 reviews)
Reichsburg Cochem is just one of the places to see in Cochem, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the riverfront.
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A historic stone building with arched windows and a dome.

Porta Nigra

9.2/10 (803 reviews)
Glimpse the ancient world when you explore the interior chambers of this Roman relic, the largest surviving city gate north of the Alps and a UNESCO World Heritage Site.
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A historic castle on a hill overlooking a calm river, with buildings and a bridge in the foreground.

Ehrenbreitstein Fortress

8.8/10 (295 reviews)
Take the cable car on a scenic journey to a mountaintop to see one of the largest preserved forts in Europe.
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A street with pink and orange buildings, a church with a tall spire, and mannequins in a shop window.

Trier Cathedral

9.4/10 (525 reviews)
Study the majestic design of this fortress-like structure, which is the largest church in the city and one of Germany’s oldest cathedrals.
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Vulkaneifel Thermal Spa

8.8/10 (53 reviews)
Explore the great outdoors at Vulkaneifel Thermal Spa, a lovely green space in Bad Bertrich. While you're in the area, stroll along the riverfront.
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Mosel Wine Region Hotel Deals

bestprice Hotel Koblenz

bestprice Hotel Koblenz

Bahnhofpl. 1 Koblenz RP
Fully refundableReserve now, pay when you stay
$68 nightly
$73 total
Sep 13 - Sep 14
Total with taxes and fees
8/10 Very Good! (86 reviews)
"Excellent breakfast"

Reviewed on Aug 30, 2026

bestprice Hotel Koblenz
Premier Inn Koblenz City

Premier Inn Koblenz City

Clemensstrasse 32 Koblenz
$92 nightly
$98 total
Sep 27 - Sep 28
Total with taxes and fees
8.4/10 Very Good! (36 reviews)
"Reception staff should be more customer focused"

Reviewed on Aug 30, 2026

Premier Inn Koblenz City
Diehls Hotel

Diehls Hotel

Rheinsteigufer 1 Koblenz RP
Fully refundableReserve now, pay when you stay
$88 nightly
$94 total
Sep 27 - Sep 28
Total with taxes and fees
8.2/10 Very Good! (300 reviews)
"Overall, it is an ok-"

Reviewed on Aug 26, 2026

Diehls Hotel
See all 3,243 properties in Mosel Wine Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mosel Wine Region Vacation Packages

Mosel Wine Region Essential Information

Language
German
Currency
Euros
Local Welcome
Guten Tag
Local Goodbye
Tschüss
Closest Airport
Frankfurt Intl. Airport (FRA)

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