Mosel Wine Region Vacations from $1,220

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Mosel Wine Region Vacation

Reserve a vacation package to Mosel Wine Region and go wherever your adventurous soul takes you. This destination has plenty to offer, including its nature, history, festivals, and so much more. Start your trip to Mosel Wine Region with some time in Trier visiting popular sights like Trier Roman Amphitheatre and Trier Christmas Market. Koblenz is another top city that draws crowds from far and wide. Deutsches Eck and Ehrenbreitstein Fortress are two of the leading places to see in this destination. Expedia has hotels, flights, car rentals and more to help you curate your very own tailored Mosel Wine Region vacation today.

The Latest Mosel Wine Region vacation packages

Price found within the past 48 hours. Click for updated prices.
BIVIUS Hotel Restaurant Luxembourg

BIVIUS Hotel Restaurant Luxembourg

$1,220
per person
Jan 5 - Jan 9
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Luxembourg (LUX)
8.2/10 Very Good! (279 reviews)
LEGERE HOTEL Luxembourg

LEGERE HOTEL Luxembourg

$1,227
per person
Jan 5 - Jan 9
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Luxembourg (LUX)
9/10 Wonderful! (919 reviews)
Parc Belair

Parc Belair

Belair
$1,243
per person
Jan 5 - Jan 9
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Luxembourg (LUX)
8.4/10 Very Good! (370 reviews)
The hotel was in a good location and the bus stop was right outside of the hotel. The room was clean, the staff were helpful and our room was upgraded due to an event that was taking place at the hotel. We had a nice view from the balcony and the bed was very comfortable. The lobby looked very nice. However, we were placed on a floor where there was tape and sheets on the floor and it wasn’t presentable for guests; it looked neglected and that they were in the middle of renovations. We shouldn’t have had this outside of our door; attention to detail matters. The upgrade didn’t come across this way due to how the corridor looked as well as the room which just looked standard. It came across that the hotel had overbooked/ assigned our original room to the guests who were at the hotel for a specific event. There was only one side table by the bed, therefore I had to use the chair in order to connect my devices and have them near to me. There was no air con in this room which was quite surprising. A manual fan was provided but did not help to keep the room cool as the room already had lots of hot air. The hotel is in a convenient location; however needs to improve in the areas outlined.

Reviewed on Jul 28, 2026

Hotel Re'serstuff

Hotel Re'serstuff

$1,253
per person
Jan 5 - Jan 9
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Luxembourg (LUX)
8.2/10 Very Good! (118 reviews)
I love it. Great place and bus stop across.

Reviewed on Oct 2, 2026

Hotel The Rose by Goeres

Hotel The Rose by Goeres

Hollerich
$1,287
per person
Jan 5 - Jan 9
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Luxembourg (LUX)
10/10 Exceptional! (12 reviews)
Very nice room in a quiet, boutique setting.

Reviewed on Sep 21, 2026

Don't see what you're looking for?
See all available trips from Columbus to Mosel Wine Region
View all trips

Where to stay in Mosel Wine Region

Find the best Mosel Wine Region areas and neighborhoods for the activities you enjoy most. Learn more about Mosel Wine Region
A large classical building with symmetrical architecture, a well-maintained garden with hedges and flower beds, and a clear sky.

Altstadt Koblenz

1 out of top 10 points of interest in this area

You'll enjoy the museums and riverfront in Altstadt Koblenz. You might want to make time for a stop at Koblenz Theatre or Koblenz Town Hall.

A historic stone building with arched windows and a dome.

Altstadt Trier

3 out of top 10 points of interest in this area

Altstadt Trier is noteworthy for its historic sites, and you can make a stop at top attractions like Trier Christmas Market and Karl Marx House.

A historic square with a prominent clock tower, traditional buildings, and a cobblestone street.

Mitte

Mitte is noteworthy for its historic sites, and you can make a stop at top attractions like Frankenturm and Trier Christmas Market.

A stone archway with a view of a river and a town below.

Historic Downtown

The restaurants and wineries are a few reasons travelers visit Historic Downtown. Want to see more of the surrounding area? Landshut Castle and Winery Dr. Loosen are a few top sights nearby.

A nighttime cityscape with a river reflecting lights, a prominent castle-like building, and a bridge.

Mitte

Unique features of Mitte include the river views and bars. Make a stop by Rhein Mosel Halle Congress Center or Rhine while you're exploring the area.

Stay near popular Mosel Wine Region attractions

A castle on a hill with a cobblestone path leading up to it.

Burg Eltz

9.0/10 (262 reviews)
You can learn about the history of Wierschem when you stop by Burg Eltz. Wander the riverfront in this quaint area.
See properties
A river with boats, a castle on a hill, and a church with a tall spire.

Moselle Promenade

9.0/10 (473 reviews)
Explore the great outdoors at Moselle Promenade, a lovely green space in Cochem. While you're in the area, stroll along the riverfront.
See properties
A river with a bridge, a statue, and a waterfront promenade with flags.

Deutsches Eck

9.0/10 (491 reviews)
Watch the boats at the meeting of two grand rivers and inspect the replica of a momentous sculpture at the German Corner.
See properties
A river with boats, a castle on a hill, and a church with a spire.

Reichsburg Cochem

9.0/10 (379 reviews)
Reichsburg Cochem is just one of the places to see in Cochem, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the riverfront.
See properties
A historic church with two towers and a large clock.

Trier Cathedral

9.4/10 (525 reviews)
Study the majestic design of this fortress-like structure, which is the largest church in the city and one of Germany’s oldest cathedrals.
See properties
A historic stone building with arched windows and a dome.

Porta Nigra

9.2/10 (803 reviews)
Glimpse the ancient world when you explore the interior chambers of this Roman relic, the largest surviving city gate north of the Alps and a UNESCO World Heritage Site.
See properties
A historic castle on a hill overlooking a calm river, with buildings and a bridge in the foreground.

Ehrenbreitstein Fortress

8.8/10 (295 reviews)
Take the cable car on a scenic journey to a mountaintop to see one of the largest preserved forts in Europe.
See properties

Vulkaneifel Thermal Spa

8.8/10 (53 reviews)
Explore the great outdoors at Vulkaneifel Thermal Spa, a lovely green space in Bad Bertrich. While you're in the area, stroll along the riverfront.
See properties

Mosel Wine Region Hotel Deals

bestprice Hotel Koblenz

bestprice Hotel Koblenz

Bahnhofpl. 1 Koblenz RP
Fully refundableReserve now, pay when you stay
$54 nightly
$58 total
Oct 18 - Oct 19
Total with taxes and fees
bestprice Hotel Koblenz
Schloss Lieser, Autograph Collection

Schloss Lieser, Autograph Collection

Moeselstrasse 33 Lieser
$165 nightly
$177 total
Nov 1 - Nov 2
Total with taxes and fees
Schloss Lieser, Autograph Collection
Mercure Hotel Trier Porta Nigra

Mercure Hotel Trier Porta Nigra

Porta-Nigra-Platz 1 Trier RP
Fully refundableReserve now, pay when you stay
$91 nightly
$101 total
Nov 16 - Nov 17
Total with taxes and fees
Mercure Hotel Trier Porta Nigra
See all 3,272 properties in Mosel Wine Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mosel Wine Region Vacation Packages

Mosel Wine Region Essential Information

Language
German
Currency
Euros
Local Welcome
Guten Tag
Local Goodbye
Tschüss
Closest Airport
Frankfurt Intl. Airport (FRA)

More vacations you might like

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.