Mosel Wine Region Vacation Packages 2026 from $1,103

Your Mosel Wine Region Vacation

Reserve a vacation package to Mosel Wine Region and go wherever your adventurous soul takes you. This destination has plenty to offer, including its nature, history, festivals, and so much more. Start your trip to Mosel Wine Region with some time in Trier visiting popular sights like Trier Roman Amphitheatre and Trier Christmas Market. Koblenz is another top city that draws crowds from far and wide. Deutsches Eck and Ehrenbreitstein Fortress are two of the leading places to see in this destination. Expedia has hotels, flights, car rentals and more to help you curate your very own tailored Mosel Wine Region vacation today.

The Latest Mosel Wine Region vacation packages

Price found within the past 48 hours. Click for updated prices.

Hotel Frankfurt Messe affiliated by Meliá

Bockenheim

$1,103

per person

Nov 30 - Dec 7

found 1 day ago

Roundtrip non-stop flight included

Washington (IAD) to Frankfurt (FRA)

7.8/10 Good! (475 reviews)

FAVORITE Parkhotel I Spa – Business – Fine Dining

Oberstadt

$1,484

per person

Dec 1 - Dec 7

found 10 hours ago

Roundtrip flight included

Washington (IAD) to Frankfurt (FRA)

8.6/10 Excellent! (291 reviews)

The hotel is very well equipped and the staff were courteous and helpful. My personal criticism is the rooms are poorly soundproofed and having the Gym on the top floor is not the best option. I could hear every dropped dumbbell. Such a shame as the location is great.

Reviewed on Aug 13, 2026

Hotel Monopol

Gutleutviertel

$1,246

per person

Dec 1 - Dec 7

found 1 day ago

Roundtrip flight included

Washington (IAD) to Frankfurt (FRA)

8.2/10 Very Good! (1,003 reviews)

Hotel Hammer - Mainz Hauptbahnhof

Mainz City Center

$1,248

per person

Nov 30 - Dec 7

found 4 hours ago

Roundtrip non-stop flight included

Washington (IAD) to Frankfurt (FRA)

9/10 Wonderful! (586 reviews)

The location next the train and an easy walk into the core was excellent for us.

Reviewed on Oct 20, 2026

Hotel Monika

$1,183

per person

Nov 30 - Dec 7

found 1 day ago

Roundtrip non-stop flight included

Washington (IAD) to Frankfurt (FRA)

9.6/10 Exceptional! (23 reviews)

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Where to stay in Mosel Wine Region

Find the best Mosel Wine Region areas and neighborhoods for the activities you enjoy most. Learn more about Mosel Wine Region

A large classical building with symmetrical architecture, a well-maintained garden with hedges and flower beds, and a clear sky.

Altstadt Koblenz

1 out of top 10 points of interest in this area

You'll enjoy the museums and riverfront in Altstadt Koblenz. You might want to make time for a stop at Koblenz Theatre or Koblenz Town Hall.

A historic stone building with arched windows and a dome.

Altstadt Trier

3 out of top 10 points of interest in this area

Altstadt Trier is noteworthy for its historic sites, and you can make a stop at top attractions like Trier Christmas Market and Karl Marx House.

A historic square with a prominent clock tower, traditional buildings, and a cobblestone street.

Mitte

Mitte is noteworthy for its historic sites, and you can make a stop at top attractions like Frankenturm and Trier Christmas Market.

A stone archway with a view of a river and a town below.

Historic Downtown

The restaurants and wineries are a few reasons travelers visit Historic Downtown. Want to see more of the surrounding area? Landshut Castle and Winery Dr. Loosen are a few top sights nearby.

A nighttime cityscape with a river reflecting lights, a prominent castle-like building, and a bridge.

Mitte

Unique features of Mitte include the river views and bars. Make a stop by Rhein Mosel Halle Congress Center or Rhine while you're exploring the area.

Stay near popular Mosel Wine Region attractions

A castle on a hill with a cobblestone path leading up to it.

Burg Eltz

9.0/10 (262 reviews)

You can learn about the history of Wierschem when you stop by Burg Eltz. Wander the riverfront in this quaint area.

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A river with a bridge, a statue, and a waterfront promenade with flags.

Deutsches Eck

9.0/10 (491 reviews)

Watch the boats at the meeting of two grand rivers and inspect the replica of a momentous sculpture at the German Corner.

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A river with boats, a castle on a hill, and a church with a tall spire.

Moselle Promenade

9.0/10 (473 reviews)

Explore the great outdoors at Moselle Promenade, a lovely green space in Cochem. While you're in the area, stroll along the riverfront.

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A river with boats, a castle on a hill, and a church with a spire.

Reichsburg Cochem

9.0/10 (379 reviews)

Reichsburg Cochem is just one of the places to see in Cochem, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the riverfront.

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Porta Nigra

9.2/10 (803 reviews)

Glimpse the ancient world when you explore the interior chambers of this Roman relic, the largest surviving city gate north of the Alps and a UNESCO World Heritage Site.

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A historic church with two towers and a large clock.

Trier Cathedral

9.4/10 (525 reviews)

Study the majestic design of this fortress-like structure, which is the largest church in the city and one of Germany’s oldest cathedrals.

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A historic castle on a hill overlooking a calm river, with buildings and a bridge in the foreground.

Ehrenbreitstein Fortress

8.8/10 (295 reviews)

Take the cable car on a scenic journey to a mountaintop to see one of the largest preserved forts in Europe.

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Trier Christmas Market

9.4/10 (33 reviews)

You can find the perfect gifts to bring home at Trier Christmas Market during your visit to Trier. Amble around the area's waterfront or experience its museums.

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Mosel Wine Region Hotel Deals

bestprice Hotel Koblenz

Bahnhofpl. 1 Koblenz RP

Fully refundableReserve now, pay when you stay

$59 nightly

$63 total

Nov 1 - Nov 2

Total with taxes and fees

8/10 Very Good! (106 reviews)

"Good location. The floor had been swept but seemed like it might have been quite a while since it had seen a mop."

Reviewed on Oct 20, 2026

Schloss Lieser, Autograph Collection

Moeselstrasse 33 Lieser

$206 nightly

$221 total

Nov 15 - Nov 16

Total with taxes and fees

Mercure Hotel Trier Porta Nigra

Porta-Nigra-Platz 1 Trier RP

Fully refundableReserve now, pay when you stay

$93 nightly

$103 total

Nov 16 - Nov 17

Total with taxes and fees

See all 3,272 properties in Mosel Wine Region

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.