Nepenthe Vacations from $640

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Your Nepenthe Vacation

Take the stress out of planning your next escape by booking a Nepenthe vacation package. Immerse yourself in the sights and sounds of this appealing neighborhood and experience everything it has to offer. Not sure where to go during your trip to Nepenthe? Nearby attractions such as Chapel of the Holy Cross, Cathedral Rock and Tlaquepaque Arts and Crafts Village are good places to start. Stop dreaming and start doing. When it's time to book your ideal vacation to Nepenthe, Expedia will help you get there.

The Latest Nepenthe Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Sedona Springs Resort

Sedona Springs Resort

3 out of 5
West Sedona
Price was $926, price is now $640 per person
$640
per person
Jun 4 - Jun 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Phoenix (PHX)
9.2/10 Wonderful! (1,282 reviews)
Hot tub perfect and private. So much room! 2 floors! Spa tub! Fireplace! Beds are super plush.

Reviewed on Mar 31, 2026

The Wilde Resort and Spa

The Wilde Resort and Spa

4 out of 5
West Sedona
Save 100% on your flight
Price was $1,593, price is now $1,077 per person
$1,077
per person
May 3 - May 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Phoenix (PHX)
9.2/10 Wonderful! (801 reviews)
good location the bed is very comfortable.

Reviewed on Mar 31, 2026

Hyatt Vacation Club at Pinon Pointe, Sedona

Hyatt Vacation Club at Pinon Pointe, Sedona

3.5 out of 5
Uptown Sedona
Save 100% on your flight
Price was $1,313, price is now $956 per person
$956
per person
May 3 - May 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Phoenix (PHX)
8.8/10 Excellent! (1,019 reviews)
Nice place, nice location. Great views. Pleasant staff. Rooms and facilities are a bit dated, considering the price. Disappointing that their policy is to only clean and make up our room one night out of the three we stayed. Disappointing that the pool kept closing for maintenance -- we were never able to access it.

Reviewed on Mar 31, 2026

Hilton Vacation Club Los Abrigados Resort & Spa Sedona

Hilton Vacation Club Los Abrigados Resort & Spa Sedona

3.5 out of 5
Chapel
Price was $930, price is now $679 per person
$679
per person
May 3 - May 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Phoenix (PHX)
9/10 Wonderful! (3,684 reviews)
Rooms worn down, carpet dirty, beds had dips on each side. Parking difficult. Amazing customer service though!

Reviewed on Apr 2, 2026

Royal Palms Resort and Spa, part of Hyatt

Royal Palms Resort and Spa, part of Hyatt

5 out of 5
Camelback East
Save 100% on your flight
Price was $2,594, price is now $1,915 per person
$1,915
per person
May 11 - May 16
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Phoenix (PHX)
9.2/10 Wonderful! (1,006 reviews)
Very nice and calming. Felt very private. Pool Area could use some work. Maybe larger. Wasn’t able to use overcrowded on high temp day in Mach. Too many people in pool and not enough shade or seating Over all beautiful and staff was amazing.

Reviewed on Mar 25, 2026

Where to stay in Nepenthe

Find the best Nepenthe areas and neighborhoods for the activities you enjoy most. Learn more about Nepenthe
West Sedona

West Sedona

2 out of top 10 points of interest in this area
4.5/5(1,948 area reviews)

Bask in the glow of red sandstone formations while exploring numerous hiking and mountain biking trails. Discover the unique turquoise-arched McDonald's and the awe-inspiring Chapel of the Holy Cross, nestled within a red rock cliff.

Find hotels in West Sedona

Nepenthe Hotel Deals

Arabella Hotel Sedona

Arabella Hotel Sedona

3.5 out of 5
725 Highway 179 Sedona Sedona AZ
Fully refundableReserve now, pay when you stay
$337 nightly
The price is $384 total per night from Apr 27 to Apr 28
$384 total
Apr 27 - Apr 28
Total with taxes and fees
9.2/10 Wonderful! (2,772 reviews)
The room balcony view was not great.breakfast was great. The guidance on trails was great.

Reviewed on Apr 2, 2026

Arabella Hotel Sedona
Sky Ranch Lodge

Sky Ranch Lodge

3.5 out of 5
1105 Airport Rd. Sedona AZ
Fully refundableReserve now, pay when you stay
$318 nightly
The price is $360 total per night from May 3 to May 4
$360 total
May 3 - May 4
Total with taxes and fees
9.6/10 Exceptional! (2,103 reviews)
Loved the view from our room. absolutely worth the upgrade. We did not have breakfast there. The Airstream ready to serve a few drinks. Will definitely be back.

Reviewed on Apr 2, 2026

Sky Ranch Lodge
Enchantment

Enchantment

4.5 out of 5
525 Boynton Canyon Rd Sedona AZ
$969 nightly
The price is $1,030 total per night from May 3 to May 4
$1,030 total
May 3 - May 4
Total with taxes and fees
9.4/10 Exceptional! (578 reviews)
We loved our trip here.

Reviewed on Apr 1, 2026

Enchantment
See all 3,156 properties in Nepenthe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Nepenthe

Oak Creek Canyon

Oak Creek Canyon

4.5/5(1,527 reviews)

Take one of Arizona’s most beautiful scenic drives through this canyon and be sure to take your hiking boots, fishing rod, swimsuit and camera along for the ride.

Oak Creek Canyon
Red Rock State Park

Red Rock State Park

4.5/5(1,149 reviews)

Enjoy a trip to Red Rock State Park and popular activities like hiking in Sedona. Stroll along the riverfront or discover the area's beautiful sunsets.

Red Rock State Park
Slide Rock State Park

Slide Rock State Park

4.5/5(735 reviews)

Swim down a natural water slide and explore a former pioneer homestead at this popular destination for outdoor fun.

Slide Rock State Park

Things to do

Sedona Boynton Canyon Trolley Tour

Sedona Boynton Canyon Trolley Tour

$26
per adult
90% of travellers recommend
Sedona Boynton Canyon Trolley Tour
Sedona Magical Sightseeing Highlight Tour- 5 Stars

Sedona Magical Sightseeing Highlight Tour- 5 Stars

$69
per adult
100% of travellers recommend
Sedona Magical Sightseeing Highlight Tour- 5 Stars
Chuck Wagon Supper & Western Stage Show at Blazin' M Ranch Ticket

Chuck Wagon Supper & Western Stage Show at Blazin' M Ranch Ticket

$99
per adult
80% of travellers recommend
Chuck Wagon Supper & Western Stage Show at Blazin' M Ranch Ticket
See all activities in Sedona
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.