
Nepenthe Vacations from $329
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Your Nepenthe Vacation
Take the stress out of planning your next escape by booking a Nepenthe vacation package. Immerse yourself in the sights and sounds of this appealing neighborhood and experience everything it has to offer. Not sure where to go during your trip to Nepenthe? Nearby attractions such as Chapel of the Holy Cross, Cathedral Rock and Tlaquepaque Arts and Crafts Village are good places to start. Stop dreaming and start doing. When it's time to book your ideal vacation to Nepenthe, Expedia will help you get there.
The Latest Nepenthe Vacation Packages

Westgate Painted Mountain Golf Resort
Reviewed on Nov 22, 2025


Raintree at Phoenix South Mountain Preserve
Reviewed on Nov 9, 2025


Sentral Sol Modern
Reviewed on Nov 22, 2025
Where to stay in Nepenthe

West Sedona
Bask in the glow of red sandstone formations while exploring numerous hiking and mountain biking trails. Discover the unique turquoise-arched McDonald's and the awe-inspiring Chapel of the Holy Cross, nestled within a red rock cliff.
Discover the most popular places to visit in Nepenthe

Oak Creek Canyon
Take one of Arizona’s most beautiful scenic drives through this canyon and be sure to take your hiking boots, fishing rod, swimsuit and camera along for the ride.

Red Rock State Park
Enjoy a trip to Red Rock State Park and popular activities like hiking in Sedona. Stroll along the riverfront or discover the area's mountain views.

Chapel of the Holy Cross
Emerging from one of Sedona’s famous walls of red rock, this chapel is a spectacular sight to behold.
Things to do

Half-day Sedona Sightseeing Tour

Sightseeing Highlights Tour of Sedona























