Palm Isles Vacations from $392

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Your Palm Isles Vacation

Make planning your travels stress-free by creating a vacation package to Palm Isles. Let us handle the minutiae, so you can focus on appreciating everything this neighborhood has to offer. Your trip to Palm Isles wouldn't be complete without exploring major attractions nearby such as Fishing Pier Fort Myers Beach, Bunche Beach and Jungle Golf Ft. Myers. Stop dreaming and start doing. When it's time to book your ideal vacation to Palm Isles, Expedia will help get you there.

The Latest Palm Isles Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Edison Beach House

Edison Beach House

3.5 out of 5
Save 100% on your flight
Price was $616, price is now $392 per person
$392
per person
Nov 25 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Fort Myers (RSW)
9.4/10 Exceptional! (1,499 reviews)
Good service and nice people

Reviewed on Oct 14, 2025

LaPlaya Beach & Golf Resort - A Noble House Resort

LaPlaya Beach & Golf Resort - A Noble House Resort

4.5 out of 5
Vanderbilt Beach
Save 100% on your flight
Price was $1,729, price is now $996 per person
$996
per person
Jan 8 - Jan 11
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
8.8/10 Excellent! (1,002 reviews)
Our experience at La Playa was exceptional, everything was what we wanted and expected it to be

Reviewed on Sep 29, 2025

The Perry Hotel Naples

The Perry Hotel Naples

4.5 out of 5
Save 100% on your flight
Price was $937, price is now $569 per person
$569
per person
Jan 8 - Jan 11
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.6/10 Exceptional! (417 reviews)
I would give it excellent but we checked out around 9pm due to a few hours of the fire alarm going off. They had the fire department there but they were still working on the problem and we were concerned we wouldn’t be able to get a good night’s sleep.

Reviewed on Oct 14, 2025

Southseas

Southseas

3 out of 5
Save 100% on your flight
Price was $3,064, price is now $1,942 per person
$1,942
per person
Jan 3 - Jan 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
No reviews
Bellasera Resort

Bellasera Resort

4 out of 5
Old Naples
Save 100% on your flight
Price was $1,638, price is now $1,057 per person
$1,057
per person
Jan 8 - Jan 11
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.6/10 Exceptional! (2,219 reviews)
Joyful, relax and exceptional place in the center of the town. People at reception thanks to Tesse and her coworker was pleasant and welcoming , menu at Claw Bar and the London Club superbly delicious , service above and beyond accommodating , dream team of the cleaning crew (spotless clean, but invisible) , valet people friendly and entertaining . Whole experience during our stay was just perfect . Thank you , Bellasera , we will be back

Reviewed on Sep 29, 2025

Where to stay in Palm Isles

Find the best Palm Isles areas and neighborhoods for the activities you enjoy most. Learn more about Palm Isles
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Mid Island

1 out of top 10 points of interest in this area
4.5/5(108 area reviews)

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

Find hotels in Mid Island

Palm Isles Hotel Deals

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $214 total per night from Oct 21 to Oct 22
$214 total
Oct 21 - Oct 22
Total with taxes and fees
8.8/10 Excellent! (1,033 reviews)
"The thing that i did not like was that the tub was small and we had to pay for parking each day. Everything else was great."

Reviewed on Oct 11, 2025

Lani Kai Beachfront Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street, Fort Myers Beach, FL
$220 nightly
The price is $246 total per night from Oct 21 to Oct 22
$246 total
Oct 21 - Oct 22
Total with taxes and fees
8.8/10 Excellent! (1,531 reviews)
"This was a great resort. I was surprised that the main hotel is across the street from the beach, but there is a bridge that makes it easy to get to the beach, pool and restaurants. We came with our teens and there were lots of families there, which made it enjoyable for all of us."

Reviewed on Oct 11, 2025

Margaritaville Beach Resort Fort Myers
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave, Fort Myers, FL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Oct 16 to Oct 17
$70 total
Oct 16 - Oct 17
Total with taxes and fees
6.4/10 (1,010 reviews)
"Location was great"

Reviewed on Oct 10, 2025

Baymont by Wyndham Fort Myers Central
See all 16,787 properties in Palm Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Palm Isles

Bunche Beach featuring general coastal views and a beach

Bunche Beach

Find a relatively obscure beach in a popular area of sand, warm water and a fascinating variety of coastal life. You’ll be thankful for the uncrowded space.

Bunche Beach
Fishing Pier Fort Myers Beach featuring a sandy beach and a bridge

Lynn Hall Memorial Park

4.5/5(786 reviews)

Walk over the water on a long pier that’s popular day and night for the breeze and fishing.

Lynn Hall Memorial Park
#kidsfun I wouldn't say feed the seagulls but there are so many nice restaurants and beach shops.

Castle Beach

Why not spend a lazy afternoon at Castle Beach during your trip to Fort Myers Beach?

Castle Beach

Things to do

Fort Myers Beach Sunset Excursion

Fort Myers Beach Sunset Excursion

$60
per adult
100% of travellers recommend
Fort Myers Beach Sunset Excursion
Southwest Florida Sunset Sail

Southwest Florida Sunset Sail

$70
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
Dolphin and Sightseeing Tiki Cruise

Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included

$65
per adult
Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included
See all activities in Fort Myers Beach
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.