Panama Vacation Rentals

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Dec 15 - Dec 16
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Dec 16 - Dec 17
This weekend
Dec 19 - Dec 21
Next weekend
Dec 26 - Dec 28

Our top choices for Panama vacation rentals

Smart TV
Spacious and charming 🌸🌸🌸

Vacation Home in Fort Smith

Spacious and charming 🌸🌸🌸
9.4 out of 10, Exceptional, (15)
"Enjoyed the screened in porch and the friendly cats in the neighborhood. We loved the house and we will be back!"
United States
Anonymous traveler
$137 nightly
The price is $156
Dec 19 - Dec 20
Total with taxes and fees
Spacious and charming 🌸🌸🌸
Interior
Fort Smith / Furnished 4 BR / Nurses, Ebbing, TDY

Vacation Home in Fort Smith

Fort Smith / Furnished 4 BR / Nurses, Ebbing, TDY
10.0 out of 10, Exceptional, (15)
"Great place to stay while visiting Fort Smith"
United States
jon c.
$375 nightly
The price is $384
Dec 19 - Dec 20
Total with taxes and fees
Fort Smith / Furnished 4 BR / Nurses, Ebbing, TDY
Microwave, oven, stovetop, dishwasher
Charming 2-bedroom townhome at centrally located Fort Smith

Vacation Home in Fort Smith

Charming 2-bedroom townhome at centrally located Fort Smith
2.0 star property
10.0 out of 10, Exceptional, (1)
"Nice cozy lovely stay!! "
United States
Amy S.
$176 nightly
The price is $201
Jan 15 - Jan 16, 2026
Total with taxes and fees
Charming 2-bedroom townhome at centrally located Fort Smith
Fridge, microwave, oven, stovetop
Conveniently located duplex!

Vacation Home in Fort Smith

Conveniently located duplex!
10.0 out of 10, Exceptional, (2)
"Perfect size for an overnight or short stay. Extremally clean, pillows were great, very comfortable bed, I likes not having to climb up into bed. It would have been perfect if there were legs on the sofa, it was rather low for our middle aged knees."
United States
Misty S.
$159 nightly
The price is $181
Dec 17 - Dec 18
Total with taxes and fees
Conveniently located duplex!
Interior
Southern Comfort Downtown Ft Smith!

Vacation Home in Fort Smith

Southern Comfort Downtown Ft Smith!
10.0 out of 10, Exceptional, (30)
"Comfortable home away from home. "
United States
Monica P.
$159 nightly
The price is $182
Dec 18 - Dec 19
Total with taxes and fees
Southern Comfort Downtown Ft Smith!
Interior
Retro Centrally Located Duplex!

Vacation Home in Fort Smith

Retro Centrally Located Duplex!
10.0 out of 10, Exceptional, (4)
"This place was fun and clean "
United States
cara s.
$150 nightly
The price is $171
Dec 17 - Dec 18
Total with taxes and fees
Retro Centrally Located Duplex!
Interior
King bed! Gameroom! Super cozy-The Treasured Mist!

Vacation Home in Fort Smith

King bed! Gameroom! Super cozy-The Treasured Mist!
9.4 out of 10, Exceptional, (3)
"The room was clean and comfortable. The bed was awesome. Very peaceful . Nice place to stay."
United States
David G.
$130 nightly
The price is $141
Dec 16 - Dec 17
Total with taxes and fees
King bed! Gameroom! Super cozy-The Treasured Mist!
Living area
Charming 3-bedroom bungalow in delightful Fort Smith with WiFi, AC

Vacation Home in Fort Smith

Charming 3-bedroom bungalow in delightful Fort Smith with WiFi, AC
9.8 out of 10, Exceptional, (24)
"Very quite beautiful space easy check in "
United States
Jalishia V.
$148 nightly
The price is $168
Dec 22 - Dec 23
Total with taxes and fees
Charming 3-bedroom bungalow in delightful Fort Smith with WiFi, AC
Interior
Large suite w/ king bed! The Blooming Garden!

Apartment in Fort Smith

Large suite w/ king bed! The Blooming Garden!
10.0 out of 10, Exceptional, (1)
"We just was there for a short getaway. it was very pleasant to be there and very quiet no problems at all."
United States
david r.
$130 nightly
The price is $141
Dec 16 - Dec 17
Total with taxes and fees
Large suite w/ king bed! The Blooming Garden!
Exterior
DOWNTOWN COZY GETAWAY

Vacation Home in Fort Smith

DOWNTOWN COZY GETAWAY
10.0 out of 10, Exceptional, (29)
"Loved the location, close to historical downtown, museums and places to eat. Easy access to everything we were interested in doing! We had a great time in Fort Smith and this cottage worked perfect for us and our sweet elderly dog! The house was just as pictured, so clean and well maintained. It had everything we needed and more. Cathy provided us with lots of information before our arrival and afterwards to make sure we were taken care of. We will definitely stay here again! "
United States
Paula O.
$166 nightly
The price is $189
Dec 22 - Dec 23
Total with taxes and fees
DOWNTOWN COZY GETAWAY
Interior
Modern stone cottage just one minute from I-40 exit 321 in Muldrow, Oklahoma.

Cottage in Muldrow

Modern stone cottage just one minute from I-40 exit 321 in Muldrow, Oklahoma.
8.0 out of 10, Very Good, (1)
"Our stay was wonderful, we had to go out and buy earing utensils but besides that everything was perfect."
United States
Resa H.
$119 nightly
The price is $132
Dec 16 - Dec 17
Total with taxes and fees
Modern stone cottage just one minute from I-40 exit 321 in Muldrow, Oklahoma.
Interior
Downtown Chop Shop house, HUGE garage pets allowed

Vacation Home in fort smith

Downtown Chop Shop house, HUGE garage pets allowed
9.8 out of 10, Exceptional, (13)
"super clean and comfortable. host is bada## with communication. me and my crew love the chop house"
United States
randall m.
$115 nightly
The price is $117
Dec 16 - Dec 17
Total with taxes and fees
Downtown Chop Shop house, HUGE garage pets allowed
Fridge, microwave, oven, stovetop
Boho Bungalow 2-bedroom house Professionally Cleaned in delightful Fort Smith

Vacation Home in Fort Smith

Boho Bungalow 2-bedroom house Professionally Cleaned in delightful Fort Smith
8.0 out of 10, Very Good, (3)
"Reasonable price"
United States
Lynn C.
$135 nightly
The price is $154
Dec 16 - Dec 17
Total with taxes and fees
Boho Bungalow 2-bedroom house Professionally Cleaned in delightful Fort Smith
Fridge, microwave, oven, stovetop
One bedroom duplex in desirable Park Hill

Vacation Home in Fort Smith

One bedroom duplex in desirable Park Hill
10.0 out of 10, Exceptional, (6)
"I enjoyed the place, very quiet area and close to some good restaurants. I plan to stay here again."
United States
Byron I.
$195 nightly
The price is $222
Dec 22 - Dec 23
Total with taxes and fees
One bedroom duplex in desirable Park Hill
1 bedroom, WiFi
Modern Downtown 1-Bedroom • Pet-Friendly Stay with Yard

Apartment in Fort Smith

Modern Downtown 1-Bedroom • Pet-Friendly Stay with Yard
10.0 out of 10, Exceptional, (1)
"This was a very cute and clean Vrbo. The location was a little hard to find, but the hostess was super quick to respond and help. I would stay here again:) "
United States
Robyn W.
$141 nightly
The price is $161
Dec 16 - Dec 17
Total with taxes and fees
Modern Downtown 1-Bedroom • Pet-Friendly Stay with Yard
Interior
Spacious 4-bedroom apartment in wonderful Fort Smith

Apartment in Fort Smith

Spacious 4-bedroom apartment in wonderful Fort Smith
2.0 star property
$133 nightly
The price is $152
Dec 16 - Dec 17
Total with taxes and fees
Spacious 4-bedroom apartment in wonderful Fort Smith
Exterior
Funkhaus of Fort Smith •Stay Funky•

Vacation Home in Fort Smith

Funkhaus of Fort Smith •Stay Funky•
10.0 out of 10, Exceptional, (21)
"Loved it and beds are comfy. Need side side tables other than that perfect "
United States
Hannah S.
$188 nightly
The price is $215
Dec 16 - Dec 17
Total with taxes and fees
Funkhaus of Fort Smith •Stay Funky•
Interior
StarLab '86 -Downtown Pet Friendly

Vacation Home in Fort Smith

StarLab '86 -Downtown Pet Friendly
10.0 out of 10, Exceptional, (1)
"Everything that was advertised plus more. Very clean and the little surprises it had was amazing. "
United States
Clint S.
$115 nightly
The price is $117
Dec 16 - Dec 17
Total with taxes and fees
StarLab '86 -Downtown Pet Friendly
Smart TV
Amazing 3-bedroom home with 2 full baths. Spacious fenced backyard. WiFi present

Vacation Home in Fort Smith

Amazing 3-bedroom home with 2 full baths. Spacious fenced backyard. WiFi present
2.0 star property
9.4 out of 10, Exceptional, (17)
"Great place to stay, very clean, easy to get into and a lot of space for our family! Will use again for sure."
United States
Chris S.
$216 nightly
The price is $247
Jan 15 - Jan 16, 2026
Total with taxes and fees
Amazing 3-bedroom home with 2 full baths. Spacious fenced backyard. WiFi present
Outdoor spa tub
Pirate Seeking crew. Downtown with hot tub!

Vacation Home in fort smith

Pirate Seeking crew. Downtown with hot tub!
10.0 out of 10, Exceptional, (43)
"We arrr mighty pleased with all the nautical details. This inn be worth it's weight in doubloons, savvy?"
United States
Rory O.
$115 nightly
The price is $117
Dec 16 - Dec 17
Total with taxes and fees
Pirate Seeking crew. Downtown with hot tub!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Walnut Inn Roland

Walnut Inn Roland

10/10 Excellent
"The rooms were completely updated. The staff was friendly and fast. Good housekeeping service. "
Karen 2-night trip
Posted 1 day ago
Walnut Inn Roland

Find out more about Panama

Everything you need to know about Panama vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panama vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panama in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $117 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panama rentals

At Expedia, we put the best Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Panama?

Yes, we offer vacation rentals close to well known attractions in Panama, or you can go with a more remote option if you're looking for a relaxing stay.

What's the top vacation rental that Panama has to offer?

StarLab '86 -Downtown Pet Friendly: This vacation home rental near Panama is located in the city center and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Kick off your shoes and enjoy yourself with a selection of games and a hot tub.

What’s there to see and do in Panama?

While you're exploring the area, Twyman Park and Davy Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Choctaw Travel Plaza and Casino and Spiro Mounds Archaeological Center.

What’s a vacation rental in Panama like?

A vacation rental is a private property you can stay in for a few weeks or just a few days in Panama. Vacation rentals offer extras like WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular option for a small group gathering.