Panama Vacations from $535
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Panama vacation packages
Price found within the past 48 hours. Click for updated prices.
Panama Hotel Deals
Cobblestone Inn & Suites - Avoca
7013 N Chestnut St Avoca IA
Fully refundableReserve now, pay when you stay
$120 nightly
$134 total
Nov 1 - Nov 2
Total with taxes and fees
Shelby Country Inn and RV Park
15 East St Shelby IA
Fully refundableReserve now, pay when you stay
$89 nightly
$100 total
Oct 12 - Oct 13
Total with taxes and fees
8/10 Very Good! (225 reviews)
"The bed was clean and bug free. The staff was friendly and helpful. But the room was disappointing. We got the same room for both stays. The bathroom was dirty with hair on the walls. The flooring was coming apart. It was really humid and muggy in the room. The gap between the bed and the wall was ..."
Reviewed on Sep 28, 2026
Days Inn by Wyndham Denison IA
502 Boyer Valley Rd Denison IA
Fully refundableReserve now, pay when you stay
$76 nightly
$85 total
Oct 12 - Oct 13
Total with taxes and fees
8.2/10 Very Good! (133 reviews)
"We enjoyed our stay--the room was clean and quiet and the staff kind and helpful."
Reviewed on Oct 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Panama Vacation Packages
Panama Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
More vacations you might like
Frequently asked questions
How much does a Panama vacation package cost?
You'll find cheap prices from $535 on Expedia for your Panama break. However, factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Panama costs.
What are the cheapest months to go to Panama?
If you're looking to snag a cheap Panama vacation package, consider planning a trip in January, June and December. You'll typically find better rates on airfares and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Panama?
The ideal length of your Panama vacation depends on what you'd like to do and see. Generally, a few days to a week will give you plenty of time to check out all the leading attractions and explore some hidden spots along the way.
How to find the best Panama package deals?
Begin your search for a Panama package deal by entering your travel dates and destination under our "Packages" tab. Then add some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and browse offers that come with big savings. If you don't find the perfect Panama package deal right away, just switch up your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Panama escape underway.
Is it cheaper to book a Panama vacation as a package?
You can enjoy significant savings on your next Panama retreat by booking a customized vacation package. Check the "Package" heading, then enter your travel dates and destination to see some great flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Panama?
If you have your Panama vacation dates confirmed, book as soon as you can to grab some awesome deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for quick escapes.
Does Expedia offer Book Now, Pay Later Panama vacation packages?
If you're like us, you love traveling but don't love the price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your Panama break over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
