Panama Vacations from $768

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Your Panama Vacation

Reserve a Panama vacation package and get ready to experience the best of this lively city. Consider staying in the neighborhood of Celoron, which is great for watersports, walking and fishing. During your trip to Panama, carve some time in your schedule for sightseeing. One of the best places to start exploring is Ashville Bay. Don't delay visiting this destination any longer. The perfect Panama vacation is a couple of clicks away with Expedia.

The Latest Panama vacation packages

Price found within the past 48 hours. Click for updated prices.
Days Inn by Wyndham Warren

Days Inn by Wyndham Warren

3 out of 5
Price was $848, price is now $768 per person
$768
per person
Jul 25 - Aug 1
found 10 hours ago
Roundtrip flight included
San Francisco (SFO) to Erie (ERI)
6.6/10 (1,001 reviews)
There was no coffee or breakfast like the advertisement showed.

Reviewed on Apr 17, 2026

La Quinta Inn & Suites by Wyndham Erie

La Quinta Inn & Suites by Wyndham Erie

3 out of 5
Price was $980, price is now $858 per person
$858
per person
Jul 25 - Aug 1
found 10 hours ago
Roundtrip flight included
San Francisco (SFO) to Erie (ERI)
6.2/10 (1,005 reviews)
the breakfast was okay

Reviewed on May 1, 2026

Hazeltine Boutique Hotel BnB

Hazeltine Boutique Hotel BnB

2 out of 5
Price was $1,233, price is now $1,098 per person
$1,098
per person
Jul 25 - Aug 1
found 10 hours ago
Roundtrip flight included
San Francisco (SFO) to Erie (ERI)
10/10 Exceptional! (93 reviews)
Wonderful experience! Comfy & cozy, very classy hotel. Beautifully decorated & an amazing historic atmosphere. Room was super comfy.

Reviewed on Apr 29, 2026

3314 Highland Ave. 4 Bedroom Home by RedAwning

3314 Highland Ave. 4 Bedroom Home by RedAwning

3.5 out of 5
Price was $2,840, price is now $2,571 per person
$2,571
per person
Jul 25 - Aug 1
found 10 hours ago
Roundtrip flight included
San Francisco (SFO) to Jamestown (JHW)
No reviews
Holiday Inn Express & Suites Jamestown by IHG

Holiday Inn Express & Suites Jamestown by IHG

2.5 out of 5
Price was $1,326, price is now $1,231 per person
$1,231
per person
Jul 25 - Aug 1
found 10 hours ago
Roundtrip flight included
San Francisco (SFO) to Jamestown (JHW)
9.2/10 Wonderful! (816 reviews)
Clean, quiet, good breakfast, easy check in and parking, good location

Reviewed on May 4, 2026

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Panama Hotel Deals

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

2.5 out of 5
6310 Old Station Road North East PA
Fully refundable
$107 nightly
The price is $121 total per night from May 14 to May 15
$121 total
May 14 - May 15
Total with taxes and fees
9/10 Wonderful! (1,196 reviews)
Great location for our trip from North Carolina to visit Niagara Falls. If you love hearing interstate traffic all night, this is the place for you. Also annoying were the other guests letting their doors slam shut (not the hotel's fault), the people above us walking heavily on their heels (also ...

Reviewed on May 7, 2026

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG
Chautauqua Harbor Hotel - Jamestown

Chautauqua Harbor Hotel - Jamestown

3.5 out of 5
10 Dunham Ave Celoron NY
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $172 total per night from May 12 to May 13
$172 total
May 12 - May 13
Total with taxes and fees
9.6/10 Exceptional! (1,003 reviews)
Very attentive staff! Great hospitality.

Reviewed on May 5, 2026

Chautauqua Harbor Hotel - Jamestown
La Quinta Inn & Suites by Wyndham Jamestown

La Quinta Inn & Suites by Wyndham Jamestown

3 out of 5
200 W 3rd St Jamestown NY
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from May 10 to May 11
$102 total
May 10 - May 11
Total with taxes and fees
8.4/10 Very Good! (1,002 reviews)
Breakfast was excellent; staff were extremely courteous and helpful

Reviewed on May 4, 2026

La Quinta Inn & Suites by Wyndham Jamestown
See all 549 properties in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Panama Vacation Packages

Panama Essential Information

Language
English
Currency
U.S dollars
Top Sights
Midway State Park, Long Point on Lake Chatauqua State Park and Chautauqua Lake

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Frequently asked questions

How much does a Panama vacation package cost?
Offering excellent value package deals from $768 on Expedia, you'll be thrilled with how little a vacation to Panama costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Panama?
If you're looking to book a cheap Panama vacation package, consider planning a trip in November, December and January. You'll usually find better prices on hotels and flights during these months — perfect for budget-conscious travelers.
How many days is enough for Panama?
Usually, a handful of days is enough to check out the top sights during your Panama vacation. However, if you want to have some time to rest or take day trips, consider extending your itinerary.
How to find the best Panama package deals?
Begin your search for a Panama package deal by entering your preferred travel dates and destination under our "Packages" tab. Then add some filters, like "Popular locations" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the ideal Panama package deal straight away, just change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Panama adventure off to a flying start.
Is it cheaper to book a Panama vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component individually. And you'll still get the freedom to create a customized Panama vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Panama?
If you're considering a spontaneous Panama getaway, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score sensational deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Panama vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Panama break over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.