Panama Vacations

Book a Hotel + Flight or Car together to unlock savings

Photo by Susan Maycrink

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Panama Vacation

Reserve a Panama vacation package and get ready to experience the best of this lively city. Consider staying in the neighborhood of Celoron, which is great for watersports, walking and fishing. During your trip to Panama, carve some time in your schedule for sightseeing. One of the best places to start exploring is Ashville Bay. Don't delay visiting this destination any longer. The perfect Panama vacation is a couple of clicks away with Expedia.

Panama Hotel Deals

Peek'n Peak Resort Trademark Collection by Wyndham

Peek'n Peak Resort Trademark Collection by Wyndham

3.5 out of 5
1405 Olde Road Clymer NY
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $117 total per night from Jan 19 to Jan 20
$117 total
Jan 19 - Jan 20
Total with taxes and fees
8.6/10 Excellent! (1,001 reviews)
Nice place to spend some time with family and friends. Rooms needs some renovation but in general it’s nice place

Reviewed on Jan 11, 2026

Peek'n Peak Resort Trademark Collection by Wyndham
Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

2.5 out of 5
6310 Old Station Road North East PA
Fully refundable
$89 nightly
The price is $101 total per night from Jan 20 to Jan 21
$101 total
Jan 20 - Jan 21
Total with taxes and fees
8.8/10 Excellent! (1,163 reviews)
Room was clean. Kids loved the pool

Reviewed on Jan 6, 2026

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG
La Quinta Inn & Suites by Wyndham Jamestown

La Quinta Inn & Suites by Wyndham Jamestown

3 out of 5
200 W 3rd St Jamestown NY
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $91 total per night from Jan 14 to Jan 15
$91 total
Jan 14 - Jan 15
Total with taxes and fees
8.2/10 Very Good! (1,010 reviews)
Clean rooms, Good breakfast and friendly staff

Reviewed on Jan 9, 2026

La Quinta Inn & Suites by Wyndham Jamestown
See all 553 properties in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Panama Vacation Packages

Panama Essential Information

Language
English
Currency
U.S dollars
Top Sights
Midway State Park, Long Point on Lake Chatauqua State Park and Chautauqua Lake

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Frequently asked questions

How much does a Panama vacation package cost?
Offering excellent value package deals on Expedia, you'll be thrilled with how little a vacation to Panama costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Panama?
If you're looking to book a cheap Panama vacation package, consider planning a trip in November, December and January. You'll usually find better prices on hotels and flights during these months — perfect for budget-conscious travelers.
How many days is enough for Panama?
Usually, a handful of days is enough to check out the top sights during your Panama vacation. However, if you want to have some time to rest or take day trips, consider extending your itinerary.
How to find the best Panama package deals?
Begin your search for a Panama package deal by entering your preferred travel dates and destination under our "Packages" tab. Then add some filters, like "Popular locations" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the ideal Panama package deal straight away, just change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Panama adventure off to a flying start.
Is it cheaper to book a Panama vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component individually. And you'll still get the freedom to create a customized Panama vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Panama?
If you're considering a spontaneous Panama getaway, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score sensational deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Panama vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Panama break over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.