Penermon Vacations from $299
Book a Hotel + Flight or Car together to unlock savings
Your Penermon Vacation
Unforgettable adventures await when you book a Penermon vacation package. Whether you're a history buff, foodie or just a traveler who loves discovering new places, there's something for everyone in this lively city. Can't wait to do a little sightseeing? Spend some time exploring top attractions such as Stoddard County Civil War Memorial Cemetery during your trip to Penermon. Your perfect Penermon vacation is a couple of clicks away. Explore hotels, airfares and more on Expedia for an adventure that's tailored to suit your travel style.
The Latest Penermon vacation packages
Price found within the past 48 hours. Click for updated prices.
EC Reed's Mercantile and Hotel
$299
per person
Nov 6 - Nov 8
found 6 hours ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
9.6/10 Exceptional! (108 reviews)
Cool setup in the Mercantile. The "Continental breakfast" was virtually non-existent, consisting of a Keurig coffeemaker, a handful of apples and bananas, and if you timed it right, Entemanns muffins. The restaurant was closed my entire time there. The room was odd-sized: low toilet, which was too close to the wall (the toilet roll holder pressed against my upper arm when sitting), and the sink was too tall (hitting me in the ribs).
Reviewed on Aug 28, 2026
Makanda Inn
$438
per person
Nov 6 - Nov 8
found 6 hours ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
10/10 Exceptional! (39 reviews)
I travel to So. Illinois annually to visit but this is my first stay at the Makanda Inn. It will not be my last. I had a very peaceful stay- after long days of family visit and running around with the grands, it was so nice to stay here where it was quiet and relaxing. Breakfast every morning was top notch and just the right portions.
Reviewed on Jul 22, 2026
Penermon Hotel Deals
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
$108 total
Sep 14 - Sep 15
Total with taxes and fees
9.6/10 Exceptional! (1,008 reviews)
"Had a very nice stay for one night while traveling. Room was clean and comfortable."
Reviewed on Aug 31, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$87 nightly
$100 total
Sep 2 - Sep 3
Total with taxes and fees
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$66 nightly
$76 total
Sep 7 - Sep 8
Total with taxes and fees
7.2/10 Good! (1,003 reviews)
"Front desk was welcoming and nice. Room was cleaned, beds were comfy. Very spacious. Quiet as well."
Reviewed on Sep 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Penermon Vacation Packages
Penermon Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Top Sights | Dexter Welcome Center Depot and Museum, The Heritage House and Keller Veteran Memorial |
More vacations you might like
Frequently asked questions
How much does a Penermon vacation package cost?
Offering excellent value package deals from $299 on Expedia, you'll be surprised at how little a vacation to Penermon costs! Our packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Penermon?
February, April and August are the best times to look for cheap Penermon vacation packages. Choosing to travel in less busy months means you can usually find reduced prices on accommodations and flights.
How many days is enough for Penermon?
Typically, a handful of days is enough to see the major sights during your Penermon vacation. But if you want to have some time to kick back or go on day trips, think about extending your trip.
How to find the best Penermon package deals?
Begin your search for a Penermon package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply a few filters, like "Popular locations" and "Property type," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the perfect Penermon package deal straight away, simply change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Penermon escape off to a flying start.
Is it cheaper to book a Penermon vacation as a package?
You can enjoy significant savings on your next Penermon break by booking a customized vacation package. Click on the "Package" heading, then enter your destination and travel dates to browse the best hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Penermon?
Enjoy fantastic discounts by reserving your flights early with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for an impromptu Penermon break.
Does Expedia offer Book Now, Pay Later Penermon vacation packages?
Set off on your dream escape to Penermon with help from Expedia's Book Now, Pay Later vacations. No need to save up or hold off until the next payday — we've teamed up with online lender Affirm to offer you flexibility and choice. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no late payment fees or extra charges, it's easy to budget for your trip and snap up cheap deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.