Quebrada San Isidro Vacations from $721

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

The Latest Quebrada San Isidro vacation packages

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $1,150, price is now $721 per person
$721
per person
Oct 11 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
Price was $3,815, price is now $2,039 per person
$2,039
per person
Nov 13 - Nov 20
just found
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
No reviews
Casa Fofo Family House

Casa Fofo Family House

3 out of 5
Price was $1,617, price is now $990 per person
$990
per person
Oct 11 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
No reviews
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Save 100% on your flight
Price was $1,533, price is now $968 per person
$968
per person
Nov 13 - Nov 20
just found
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
9.4/10 Exceptional! (111 reviews)
The grounds where beautiful and the staff was so friendly.

Reviewed on Jul 19, 2025

La Coralina Island House

La Coralina Island House

3.5 out of 5
Save 100% on your flight
Price was $1,953, price is now $1,288 per person
$1,288
per person
Nov 13 - Nov 20
just found
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
9.4/10 Exceptional! (84 reviews)
Wow! This resort is absolutely amazing! Bekar went above and beyond for us! He even brought in a TV to the lobby so we could watch the NHL playoff game! Food is 10/10 as well. We will definitely go back!

Reviewed on May 18, 2025

Don't see what you're looking for?
See all available trips from Columbus to Quebrada San Isidro
View all trips

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Quebrada San Isidro vacation package cost?
You can grab a vacation package to this popular destination from $721 on Expedia. But how much your vacation to Quebrada San Isidro costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to Quebrada San Isidro?
July, September and December are the best times to look for cheap Quebrada San Isidro vacation packages. Traveling in less busy months means you can usually find reduced prices on flights and accommodations.
How many days is enough for Quebrada San Isidro?
The ideal duration of your Quebrada San Isidro vacation depends on what you'd like to see and do. Generally, a handful of days to a week will give you enough time to check out all the leading attractions and discover some hidden treasures along the way.
How to find the best Quebrada San Isidro package deals?
Start your search for a Quebrada San Isidro package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the ideal Quebrada San Isidro package deal straight away, simply tweak your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Quebrada San Isidro escape off to a flying start.
Is it cheaper to book a Quebrada San Isidro vacation as a package?
You can enjoy significant savings on your Quebrada San Isidro escape by booking a tailored vacation package. Check the "Package" heading, then enter your destination and travel dates to view the best hotel prices and airfares. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Quebrada San Isidro?
If you're considering a spontaneous Quebrada San Isidro getaway, browse our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Quebrada San Isidro vacation packages?
Your Quebrada San Isidro getaway is meant to be an escape from your busy life, not a reason for money-related stress. So to allow you that extra flexibility, we've partnered with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.