Quebrada San Isidro Vacations from $901

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The Latest Quebrada San Isidro vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,260, price is now $901 per person
$901
per person
Aug 1 - Aug 6
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (5,433 reviews)
Excellent hotel with very helpful staff 5 stars!!!

Reviewed on May 22, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,873, price is now $1,189 per person
$1,189
per person
Aug 1 - Aug 6
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,017 reviews)
Central to everything

Reviewed on May 20, 2026

Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Calidonia
Save 100% on your flight
Price was $2,117, price is now $1,431 per person
$1,431
per person
Jul 6 - Jul 13
found 21 hours ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.

Reviewed on Jul 26, 2025

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,521, price is now $1,048 per person
$1,048
per person
Aug 1 - Aug 6
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,524 reviews)
It's an ok Hotel, however for the second time my shower drain has issues and the cleaning in that area could be better.

Reviewed on May 20, 2026

Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Price was $1,780, price is now $1,354 per person
$1,354
per person
Jul 30 - Aug 4
found 7 hours ago
Roundtrip flight included
Georgetown (GEO) to Panama City (PTY)
9.8/10 Exceptional! (27 reviews)
In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.

Reviewed on Mar 12, 2026

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Quebrada San Isidro Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós

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Frequently asked questions

How much does a Quebrada San Isidro vacation package cost?
You can grab a vacation package to this popular destination from $901 on Expedia. But how much your vacation to Quebrada San Isidro costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to Quebrada San Isidro?
July, September and December are the best times to look for cheap Quebrada San Isidro vacation packages. Traveling in less busy months means you can usually find reduced prices on flights and accommodations.
How many days is enough for Quebrada San Isidro?
The ideal duration of your Quebrada San Isidro vacation depends on what you'd like to see and do. Generally, a handful of days to a week will give you enough time to check out all the leading attractions and discover some hidden treasures along the way.
How to find the best Quebrada San Isidro package deals?
Start your search for a Quebrada San Isidro package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the ideal Quebrada San Isidro package deal straight away, simply tweak your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Quebrada San Isidro escape off to a flying start.
Is it cheaper to book a Quebrada San Isidro vacation as a package?
You can enjoy significant savings on your Quebrada San Isidro escape by booking a tailored vacation package. Check the "Package" heading, then enter your destination and travel dates to view the best hotel prices and airfares. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Quebrada San Isidro?
If you're considering a spontaneous Quebrada San Isidro getaway, browse our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Quebrada San Isidro vacation packages?
Your Quebrada San Isidro getaway is meant to be an escape from your busy life, not a reason for money-related stress. So to allow you that extra flexibility, we've partnered with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.