Roxana Vacations from $371

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Your Roxana Vacation

Let our vacation packages to Roxana inspire your next escape. There's tons to love about this exciting city, starting with the neighborhood of Old Jamestown, which is great for nature and walking. Fill your free time with tours of Fast Eddies Bon Air, Robert Wadlow Statue and Lewis and Clark Interpretive Center, some of the top attractions you should see during your trip to Roxana. Your dream Roxana vacation is a few clicks away. Search hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.

The Latest Roxana vacation packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $753, price is now $371 per person
$371
per person
Jun 12 - Jun 14
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,639 reviews)
The entire stay was incredible

Reviewed on May 7, 2026

Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Save 100% on your flight
Price was $668, price is now $426 per person
$426
per person
Jul 26 - Aug 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.4/10 Very Good! (819 reviews)
Room decent but customer service was excellent. Breakfast should be free

Reviewed on May 4, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $903, price is now $614 per person
$614
per person
Jul 26 - Aug 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,006 reviews)
It has a very quaintly English theme. Very unique and fun.

Reviewed on May 8, 2026

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
Downtown West
Save 100% on your flight
Price was $1,037, price is now $734 per person
$734
per person
Jul 26 - Aug 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (1,819 reviews)
Really cool hotel with great onsite bar/restaurant, gym, pool and art gallery.

Reviewed on May 6, 2026

Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
Woodson Terrace
Save 100% on your flight
Price was $764, price is now $551 per person
$551
per person
Jul 26 - Aug 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.6/10 Good! (1,000 reviews)
Overpriced for an old run down hotel. Elevator was broken, hotel room door lower hall large slanted. So much so that you could see under the door so I had to use a towel. Paint chipping and bad plumbing and crumbs in corner common areas meaning they don’t deep vacuum. Breakfast looked good but I did not partake. Bar area was the best as well as the staff there. We checked out ASAP.

Reviewed on May 5, 2026

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Roxana Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from May 25 to May 26
$149 total
May 25 - May 26
Total with taxes and fees
8.6/10 Excellent! (4,060 reviews)
Very clean

Reviewed on May 8, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from May 10 to May 11
$116 total
May 10 - May 11
Total with taxes and fees
8.8/10 Excellent! (3,194 reviews)
None

Reviewed on May 8, 2026

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from May 31 to Jun 1
$173 total
May 31 - Jun 1
Total with taxes and fees
9/10 Wonderful! (1,823 reviews)
Really cool hotel with great onsite bar/restaurant, gym, pool and art gallery.

Reviewed on May 6, 2026

21C Museum Hotel St Louis
See all 1,437 properties in Roxana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Roxana Vacation Packages

Roxana Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)
Population
1,500
Top Sights
Splash City Family Waterpark, National Great Rivers Museum and Gateway Fun Park

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Frequently asked questions

How much does a Roxana vacation package cost?
You'll find cheap prices from $371 on Expedia for your Roxana escape. However, a range of factors like the hotel choice, length of stay and season will influence how much your vacation to Roxana costs.
What are the cheapest months to go to Roxana?
If you're looking to book a cheap Roxana vacation package, consider planning a trip in November, December and January. You're likely to find lower prices on accommodations and flights during these months — perfect for a budget-friendly getaway.
How many days is enough for Roxana?
With a well-organized travel plan, you can easily visit the main Roxana sights in a few days. But if you'd like to venture off the beaten track or go on day tours, think about booking your Roxana vacation for longer.
How to find the best Roxana package deals?
Use Expedia's filter tool to help you find some terrific Roxana package deals. When you start your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your escape for midweek, or search for Roxana package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Roxana vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, car rental and hotel into one great-value price and enjoy significant savings. You'll generally snag a better deal than booking each component separately. And you'll still get the flexibility to create a customized Roxana vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Roxana?
If you've got your Roxana vacation dates confirmed, book as early as you can to grab some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are great for setting off on a whim.
Does Expedia offer Book Now, Pay Later Roxana vacation packages?
If you're like us, you love discovering new places but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Roxana vacation over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.