Roxana Vacations from $277

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Roxana Vacation

Let our vacation packages to Roxana inspire your next escape. There's tons to love about this exciting city, starting with the neighborhood of Old Jamestown, which is great for nature and walking. Fill your free time with tours of Fast Eddies Bon Air, Robert Wadlow Statue and Lewis and Clark Interpretive Center, some of the top attractions you should see during your trip to Roxana. Your dream Roxana vacation is a few clicks away. Search hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.

The Latest Roxana vacation packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Save 100% on your flight
Price was $378, price is now $277 per person
$277
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again.

Reviewed on Dec 22, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $712, price is now $353 per person
$353
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Clean room and easy parking.

Reviewed on Feb 2, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $495, price is now $362 per person
$362
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
The Cheshire is in a class by itself. The halls and sitting areas are so full of history and there’s an ambiance that we just love. Our suite, Treasure Island, was amazing! Large, clean, luxurious and cozy with a beautiful fireplace and large jacuzzi. We had a delicious dinner at the Basso, relaxed in the very British, cozy Fox & Hound, enjoyed a coffee at the Tudor styled Starbucks and as always, enjoyed breakfast beside the fireplace. We loved our stay!

Reviewed on Jan 28, 2026

Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

4 out of 5
Downtown St. Louis
Save 100% on your flight
Price was $573, price is now $420 per person
$420
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (458 reviews)
Property and room was really nice. I will be staying here in the future

Reviewed on Nov 25, 2025

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Save 100% on your flight
Price was $534, price is now $393 per person
$393
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.4/10 Very Good! (1,006 reviews)
The room was great. I enjoyed my stay.

Reviewed on Feb 3, 2026

Don't see what you're looking for?
See all available trips from Columbus to Roxana
View all trips

Roxana Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Feb 22 to Feb 23
$162 total
Feb 22 - Feb 23
Total with taxes and fees
9/10 Wonderful! (1,594 reviews)
Everything was great i can’t wait to stay again

Reviewed on Feb 6, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $112 total per night from Feb 8 to Feb 9
$112 total
Feb 8 - Feb 9
Total with taxes and fees
8.8/10 Excellent! (3,081 reviews)
Lovely hotel. Great breakfast

Reviewed on Jan 29, 2026

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $152 total per night from Feb 28 to Mar 1
$152 total
Feb 28 - Mar 1
Total with taxes and fees
8.4/10 Very Good! (4,017 reviews)
Nice room & friendly staff!

Reviewed on Jan 28, 2026

Hyatt Regency St. Louis at The Arch
See all 1,382 properties in Roxana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Roxana Vacation Packages

Roxana Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)
Population
1,500
Top Sights
Splash City Family Waterpark, National Great Rivers Museum and Gateway Fun Park

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Roxana vacation package cost?
You'll find cheap prices from $277 on Expedia for your Roxana escape. However, a range of factors like the hotel choice, length of stay and season will influence how much your vacation to Roxana costs.
What are the cheapest months to go to Roxana?
If you're looking to book a cheap Roxana vacation package, consider planning a trip in November, December and January. You're likely to find lower prices on accommodations and flights during these months — perfect for a budget-friendly getaway.
How many days is enough for Roxana?
With a well-organized travel plan, you can easily visit the main Roxana sights in a few days. But if you'd like to venture off the beaten track or go on day tours, think about booking your Roxana vacation for longer.
How to find the best Roxana package deals?
Use Expedia's filter tool to help you find some terrific Roxana package deals. When you start your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your escape for midweek, or search for Roxana package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Roxana vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, car rental and hotel into one great-value price and enjoy significant savings. You'll generally snag a better deal than booking each component separately. And you'll still get the flexibility to create a customized Roxana vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Roxana?
If you've got your Roxana vacation dates confirmed, book as early as you can to grab some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are great for setting off on a whim.
Does Expedia offer Book Now, Pay Later Roxana vacation packages?
If you're like us, you love discovering new places but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Roxana vacation over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.