Saint Charles Vacations from $618

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Your Saint Charles Vacation

With a vacation package to Saint Charles, say goodbye to travel planning and hello to stress-free adventure. Every detail of your journey has been taken care of before departing, so you can get on with experiencing this exciting city. Imes Bridge is one of the famous attractions to check off your to-do list during a trip to Saint Charles. Whoever you're traveling with and whatever you want to spend, your ultimate Saint Charles vacation is only clicks away with Expedia.

The Latest Saint Charles vacation packages

Price found within the past 48 hours. Click for updated prices.
Microtel Inn & Suites by Wyndham Ames

Microtel Inn & Suites by Wyndham Ames

2 out of 5
Price was $698, price is now $618 per person
$618
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
7.8/10 Good! (1,002 reviews)
The hotel is a bit dated and the room is small, however the room was clean, it was quiet, good breakfast, and the staff was friendly. I will definitely stay here again.

Reviewed on Jun 11, 2026

AmericInn by Wyndham Ames

AmericInn by Wyndham Ames

3 out of 5
Price was $777, price is now $682 per person
$682
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
8.4/10 Very Good! (1,000 reviews)
The owners were there late at night and early in thehe morning. They were extremely helpful and very friendly.

Reviewed on Jun 10, 2026

Iowa House

Iowa House

3 out of 5
Price was $767, price is now $685 per person
$685
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
9.6/10 Exceptional! (843 reviews)
The space was clean and breakfast was delicious.

Reviewed on Jun 3, 2026

Days Inn by Wyndham Ames

Days Inn by Wyndham Ames

2 out of 5
Price was $688, price is now $619 per person
$619
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
6.2/10 (956 reviews)
We saw no actual staff the whole stay. The breakfast was very minimal with some expired foods.

Reviewed on Apr 19, 2026

Microtel Inn & Suites by Wyndham Colfax/Newton

Microtel Inn & Suites by Wyndham Colfax/Newton

2 out of 5
Price was $698, price is now $638 per person
$638
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
7.6/10 Good! (610 reviews)
Wifi did not work and the hotel is old and in need of updates

Reviewed on May 27, 2026

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Saint Charles Hotel Deals

Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

3 out of 5
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jun 21 to Jun 22
$114 total
Jun 21 - Jun 22
Total with taxes and fees
9.2/10 Wonderful! (1,018 reviews)
"roof leaked onto bed and they knew that room was a problem"

Reviewed on Jun 13, 2026

Fairfield Inn and Suites by Marriott Des Moines West
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from Jul 3 to Jul 4
$146 total
Jul 3 - Jul 4
Total with taxes and fees
9.6/10 Exceptional! (1,185 reviews)
"It was great"

Reviewed on Jun 11, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Jun 24 to Jun 25
$79 total
Jun 24 - Jun 25
Total with taxes and fees
8.6/10 Excellent! (1,822 reviews)
"Parking was easy and spacious, stayed in a non-smoking room and didn’t have a whiff of smoke at all. Can’t comment on breakfast as we chose to sleep in, but from 4am-10am the longest I’ve ever seen from a hotel which was awesome. Rooms were clean and spacious, the bed was comfortable and the bathroom ..."

Reviewed on Jun 12, 2026

Days Inn & Suites by Wyndham Des Moines Airport
See all 637 properties in Saint Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Saint Charles Vacation Packages

Saint Charles Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Des Moines Intl. Airport (DSM)
Population
650
Top Sights
Lake Ahquabi State Park, The Winterset Stage and Holliwell Bridge

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Frequently asked questions

How much does a Saint Charles vacation package cost?
Offering excellent value package deals from $618 on Expedia, you'll be surprised at how little a vacation to Saint Charles costs! Expedia's packages make travel planning easier and your savings go further.
What are the cheapest months to go to Saint Charles?
If you're looking to book a cheap Saint Charles vacation package, consider traveling in November, December and January. You'll generally find better rates on flights and accommodations during these months — ideal for budget-conscious travelers.
How many days is enough for Saint Charles?
The ideal length for your Saint Charles vacation depends on what you'd like to do and see. Typically, a few days to a week will give you enough time to visit all the main attractions and explore some hidden treasures along the way.
How to find the best Saint Charles package deals?
Bagging a cheap Saint Charles package deal is a cinch with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply some filters and browse what's available. You can customize your search by "Amenities," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to view the most affordable Saint Charles package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a Saint Charles vacation as a package?
An Expedia vacation package could land you great savings when compared to booking flights and accommodations separately. Better still, you can customize your Saint Charles getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Saint Charles?
If you're planning an impromptu Saint Charles trip, check out our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can score amazing deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Saint Charles vacation packages?
Secure your perfect escape to Saint Charles with help from Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait until payday — we've joined forces with online lender Affirm to give you more flexibility and choice. Our vacation packages with payment plans allow you to spread the total cost over 3, 6 or 12 months. With no hidden or late payment fees, you can easily stick to your budget and snap up cheap deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.