
Saint Charles Vacations from $618
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Your Saint Charles Vacation
With a vacation package to Saint Charles, say goodbye to travel planning and hello to stress-free adventure. Every detail of your journey has been taken care of before departing, so you can get on with experiencing this exciting city. Imes Bridge is one of the famous attractions to check off your to-do list during a trip to Saint Charles. Whoever you're traveling with and whatever you want to spend, your ultimate Saint Charles vacation is only clicks away with Expedia.
The Latest Saint Charles vacation packages
Price found within the past 48 hours. Click for updated prices.

Microtel Inn & Suites by Wyndham Ames
Price was $698, price is now $618 per person
$618
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
7.8/10 Good! (1,002 reviews)
The hotel is a bit dated and the room is small, however the room was clean, it was quiet, good breakfast, and the staff was friendly. I will definitely stay here again.
Reviewed on Jun 11, 2026

AmericInn by Wyndham Ames
Price was $777, price is now $682 per person
$682
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
8.4/10 Very Good! (1,000 reviews)
The owners were there late at night and early in thehe morning. They were extremely helpful and very friendly.
Reviewed on Jun 10, 2026


Days Inn by Wyndham Ames
Price was $688, price is now $619 per person
$619
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
6.2/10 (956 reviews)
We saw no actual staff the whole stay. The breakfast was very minimal with some expired foods.
Reviewed on Apr 19, 2026

Microtel Inn & Suites by Wyndham Colfax/Newton
Price was $698, price is now $638 per person
$638
per person
Jul 30 - Aug 3
found 3 hours ago
Roundtrip non-stop flight included
Orlando (ORL) to Des Moines (DSM)
7.6/10 Good! (610 reviews)
Wifi did not work and the hotel is old and in need of updates
Reviewed on May 27, 2026
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Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jun 21 to Jun 22
$114 total
Jun 21 - Jun 22
Total with taxes and fees
9.2/10 Wonderful! (1,018 reviews)
"roof leaked onto bed and they knew that room was a problem"
Reviewed on Jun 13, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from Jul 3 to Jul 4
$146 total
Jul 3 - Jul 4
Total with taxes and fees
9.6/10 Exceptional! (1,185 reviews)
"It was great"
Reviewed on Jun 11, 2026

Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Jun 24 to Jun 25
$79 total
Jun 24 - Jun 25
Total with taxes and fees
8.6/10 Excellent! (1,822 reviews)
"Parking was easy and spacious, stayed in a non-smoking room and didn’t have a whiff of smoke at all. Can’t comment on breakfast as we chose to sleep in, but from 4am-10am the longest I’ve ever seen from a hotel which was awesome. Rooms were clean and spacious, the bed was comfortable and the bathroom ..."
Reviewed on Jun 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Saint Charles Vacation Packages
Saint Charles Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Des Moines Intl. Airport (DSM) |
Population | 650 |
Top Sights | Lake Ahquabi State Park, The Winterset Stage and Holliwell Bridge |
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