San Defendente Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

Check prices for these dates

In two weeks
Dec 26 - Dec 28
In two months
Feb 6 - Feb 8
In three months
Mar 6 - Mar 8
In four months
Apr 3 - Apr 5

Vacation Rentals in San Defendente

Exterior
Cascina Sant'Antonio

Cascina Sant'Antonio

Roddi
8.0 out of 10, Very Good, (14)
"Ras"
United States
Antonio
$78 nightly
The price is $86
Jan 8 - Jan 9, 2026
Total with taxes and fees
Cascina Sant'Antonio
Terrace/patio
Villa with vineyards, infinity pool, views of an UNESCO castle and the alps.

Villa with vineyards, infinity pool, views of an UNESCO castle and the alps.

Castagnole delle Lanze
10.0 out of 10, Exceptional, (55)
"So nice house in a pefect area with the best view and a lovely pool "
Denmark
Kim A.
Villa with vineyards, infinity pool, views of an UNESCO castle and the alps.
Terrace/patio
Felicin - Palazzo Boeri Panoramic Suites

Felicin - Palazzo Boeri Panoramic Suites

Monforte d'Alba
9.4 out of 10, Exceptional, (26)
"The property was nice with an absolutely amazing view from our apartment. The property’s restaurant was world class. "
United States
Diane
Felicin - Palazzo Boeri Panoramic Suites
Outdoor pool, sun loungers
Wellness Suite Na Canunà

Wellness Suite Na Canunà

Roddi
9.6 out of 10, Exceptional, (14)
"This place was spotless and very entertaining. Very modern and that threw us a bit. The owner was amazing and welcomed us and walked us through the electronic stuff. "
United States
Georgia
$151 nightly
The price is $169
Jan 4 - Jan 5, 2026
Total with taxes and fees
Wellness Suite Na Canunà
Interior entrance
Palazzo Centro

Palazzo Centro

Nizza Monferrato
9.0 out of 10, Wonderful, (51)
"The accommodation was basic but had what we needed for our stay. The Manager was very communicative and friendly. Breadfast vouchers for local cafes. "
United Kingdom
James
$82 nightly
The price is $95
Dec 15 - Dec 16
Total with taxes and fees
Palazzo Centro
Outdoor pool
Cascina Teresina vacation home with Pool - Monferrato -

Cascina Teresina vacation home with Pool - Monferrato -

Vanara
9.8 out of 10, Exceptional, (8)
"We were a group of 9 girls and had the best 3 days staying here. Alessio and Anna were incredible hosts and so helpful when we asked about arranging activities and taxis. It was a joy to stay here and we all said we’d love to go back. Only problem was we didn’t stay long enough and were all sad to leave. Thank you for having us ☺️"
United Kingdom
Alex G.
Cascina Teresina vacation home with Pool - Monferrato -
Property grounds
Beautifully restored farmhouse with pool immersed in the greenery

Beautifully restored farmhouse with pool immersed in the greenery

MAGLIANO ALFIERI
9.4 out of 10, Exceptional, (23)
"Property was just as listed. It was very comfortable and we really enjoyed our stay. Elena met us as we drove up and explained everything to us about the property. Had a wine tasting in the cellar of the house and we were very impressed with the whole affair. Would recommend the property to anyone wanting to visit the area."
United States
Patrick R.
Beautifully restored farmhouse with pool immersed in the greenery
Front of property
AlbaResidence Vico01

AlbaResidence Vico01

Alba
10.0 out of 10, Exceptional, (2)
$122 nightly
The price is $138
Dec 17 - Dec 18
Total with taxes and fees
AlbaResidence Vico01
Interior
This is Italian elegance with a touch of country house charm.

This is Italian elegance with a touch of country house charm.

barolo
$2,450 nightly
The price is $2,450
Dec 10 - Dec 11
Total with taxes and fees
This is Italian elegance with a touch of country house charm.
Outdoor pool
CASA DEL PRATO Farmhouse surrounded by greenery

CASA DEL PRATO Farmhouse surrounded by greenery

Roccaverano
10.0 out of 10, Exceptional, (3)
"Our stay in the house was amazing. The house is really beautiful and so is the garden and the surroundings. The hosts, Davide and Rolanda, where so nice and helpful toward us during our visit. If you plan to visit Piedmont, chose this house!"
Sweden
Fredrik S.
$399 nightly
The price is $399
Dec 9 - Dec 10
Total with taxes and fees
CASA DEL PRATO Farmhouse surrounded by greenery
Private kitchen
Appartamento Teresa

Appartamento Teresa

Asti
Appartamento Teresa
Classic Apartment | Desk, laptop workspace, free WiFi, bed sheets
San Martino Holiday Apartments

San Martino Holiday Apartments

Nizza Monferrato
10.0 out of 10, Exceptional, (3)
"Clean, beautiful, functional."
United States
Sayaka
$86 nightly
The price is $99
Dec 9 - Dec 10
Total with taxes and fees
San Martino Holiday Apartments
Front of property
Rivetto Suites

Rivetto Suites

Alba
10.0 out of 10, Exceptional, (33)
"Immaculate suite in great Alba location. Easy walk to great restaurants and shopping."
United States
Chong
Rivetto Suites
Outdoor pool, a heated pool
Villa Anna luxury and private pool in Alba

Villa Anna luxury and private pool in Alba

Italia, ALBA
10.0 out of 10, Exceptional, (15)
"We were there for 5 days to experience the Wine and Food of the Alba / Langhe region. Giulio was a great host and was very informative of the area with good suggestions for restaurants and other activities. It was a hot week while we were there and the pool was a delight. The views from the house were wonderful and the place was very quiet and peaceful. We would definitely stay here again when we come back to the region and would recommend to our friends."
United States
Cale R.
Villa Anna luxury and private pool in Alba
Family Apartment, 2 Bedrooms | Private kitchen | Coffee/tea maker, electric kettle, highchair, cleaning supplies
La Rosa Gialla

La Rosa Gialla

Barolo
10.0 out of 10, Exceptional, (36)
"We very much enjoyed our stay. Marina and Valentina were wonderful hosts, and we look forward to visiting again! "
United States
Rachel
La Rosa Gialla
Exterior
A vacation in the midst of nature just a stone's throw from Alba?

A vacation in the midst of nature just a stone's throw from Alba?

Alba
10.0 out of 10, Exceptional, (6)
"Check in easy and very friendly. Cristina hosted us in her lovely property for 4 nights which was impeccable. The details of the property are beyond description, and the hosts are the most welcoming people I ever met. Thank you for this lovely stay.. we will be back… "
Canada
Betty
A vacation in the midst of nature just a stone's throw from Alba?
Dining
Cà Mia, cozy apartment in the heart of the Roero 20 minutes from Alba.

Cà Mia, cozy apartment in the heart of the Roero 20 minutes from Alba.

Montà
Cà Mia, cozy apartment in the heart of the Roero 20 minutes from Alba.
Interior
VILLA WITH A VIEW - PRIVATE POOL AND BARBECUE

VILLA WITH A VIEW - PRIVATE POOL AND BARBECUE

Piemonte
VILLA WITH A VIEW - PRIVATE POOL AND BARBECUE
Outdoor pool
Villa "Piemonte" Pool & Whirlpool, AC, WLAN, BBQ, Slow Food & Peace❣

Villa "Piemonte" Pool & Whirlpool, AC, WLAN, BBQ, Slow Food & Peace❣

Tigliole
9.6 out of 10, Exceptional, (45)
"We had a nice stay and Irina is a great host. I recommend to order an on site dinner. The WIFI should be improved."
Netherlands
Tamás K.
Villa "Piemonte" Pool & Whirlpool, AC, WLAN, BBQ, Slow Food & Peace❣
Terrace/patio
LA MARTINA VILLA,luxury villa upon vineyards with a private swimming pool

LA MARTINA VILLA,luxury villa upon vineyards with a private swimming pool

Piedmont, Canelli
7.6 out of 10, Good, (7)
"The vila is very nice, with good views and near cute towns and villages. Unfortunately it wasn’t very clean. A lot of dog hairs, and equipment to clean was missing. Even a drying rack for laundry was missing. The glasses and cutlery was not that much. We had to gather all the equipment from the apartments to cook and eat properly. Overall very nice, but we had a lot of contact with the owner to get the stuff we wanted."
Netherlands
Koen v.
$545 nightly
The price is $545
Dec 10 - Dec 11
Total with taxes and fees
LA MARTINA VILLA,luxury villa upon vineyards with a private swimming pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top San Defendente Hotel Reviews

Hotel Calissano

Hotel Calissano

10/10 Excellent
"Friendly staff and attentive."
Andres 2-night trip
Posted 9 days ago
Hotel Calissano

Find out more about San Defendente

Everything you need to know about San Defendente vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the San Defendente vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect San Defendente vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

San Defendente vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in San Defendente. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit San Defendente in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $86 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on San Defendente rentals

At Expedia, we put the best San Defendente vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top San Defendente rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream San Defendente vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around San Defendente. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in San Defendente?

Yes, we offer vacation rentals near the most popular points of interest in San Defendente, or you can choose a secluded option if you're looking for relaxation.

What are some of the best vacation home rentals in San Defendente?

CASA DEL PRATO Farmhouse surrounded by greenery: Visitors like this San Defendente vacation home rental. It is located in a rural location and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a balcony, a garden, and a selection of games so you can immerse yourself in your vacation.

What’s there to see and do in San Defendente?

While exploring the area, visit family-friendly sights like Centro Sportivo Roero, or get outside and enjoy nature at Vineyard Landscape of Piedmont: Langhe-Roero and Monferrato. In the larger area, you’ll find Monta d'Alba Castle and Castle of Magliano Alfieri.

What’s a vacation rental in San Defendente like?

Vacation rentals are privately owned properties you can book for a long or short time in San Defendente. Vacation rentals feature amenities like kitchens and laundry facilities so you'll have all the conveniences of home. If you're concerned about a clean environment, a vacation rental can offer a sense of privacy away from public hotel elevators and busy front desks while still allowing you to travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for families.