---
title: "Top 10 Hotels in San Isidro (from $45) 2026 - Competitive Prices | Expedia"
description: "Find 17 of the best hotels in San Isidro in 2026. Compare room rates, hotel reviews and availability. Most hotels are fully refundable."
canonical: "https://www.expedia.com/San-Isidro-Hotels.d553248635975849120.Travel-Guide-Hotels"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-13T00:54:21Z
---

Plan your trip

- [San Isidro Travel Guide](https://www.expedia.com/San-Isidro.dx553248635975849120)
- [Flights to San Isidro](https://www.expedia.com/Cheap-Flights-To-San-Isidro.d553248635975849120.Travel-Guide-Flights)
- [Car Rentals in San Isidro](https://www.expedia.com/Car-Rentals-In-San-Isidro.d553248635975849120.Car-Rental-Guide)
- [San Isidro Vacation Packages](https://www.expedia.com/San-Isidro.d553248635975849120.Destination-Travel-Guides)
- [Vacation Rentals in San Isidro](https://www.expedia.com/San-Isidro-Vacation-Rentals.d553248635975849120.Travel-Guide-VacationRentals)

# Find hotels in San Isidro from $45

## Go beyond your typical stay in San Isidro

[Pet friendly](https://www.expedia.com/Hotel-Search?destination=San%20Isidro,%20Matagalpa%20Department,%20Nicaragua&regionId=553248635975849120&latLong=12.930577,-86.194393&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=PETS)

[Pool](https://www.expedia.com/Hotel-Search?destination=San%20Isidro,%20Matagalpa%20Department,%20Nicaragua&regionId=553248635975849120&latLong=12.930577,-86.194393&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=POOL)

[Family friendly](https://www.expedia.com/Hotel-Search?destination=San%20Isidro,%20Matagalpa%20Department,%20Nicaragua&regionId=553248635975849120&latLong=12.930577,-86.194393&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&travelerType=family%5Ffriendly)

[Spa](https://www.expedia.com/Hotel-Search?destination=San%20Isidro,%20Matagalpa%20Department,%20Nicaragua&regionId=553248635975849120&latLong=12.930577,-86.194393&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=SPA%5FON%5FSITE)

[Resort](https://www.expedia.com/Hotel-Search?destination=San%20Isidro,%20Matagalpa%20Department,%20Nicaragua&regionId=553248635975849120&latLong=12.930577,-86.194393&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&lodging=HOTEL%5FRESORT)

[Apart­ment](https://www.expedia.com/Hotel-Search?destination=San%20Isidro,%20Matagalpa%20Department,%20Nicaragua&regionId=553248635975849120&latLong=12.930577,-86.194393&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&lodging=APARTMENT)

[Waterpark](https://www.expedia.com/Hotel-Search?destination=San%20Isidro,%20Matagalpa%20Department,%20Nicaragua&regionId=553248635975849120&latLong=12.930577,-86.194393&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=WATER%5FPARK)

[Condo](https://www.expedia.com/Hotel-Search?destination=San%20Isidro,%20Matagalpa%20Department,%20Nicaragua&regionId=553248635975849120&latLong=12.930577,-86.194393&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&lodging=CONDO)

## Check prices for these dates

[Check prices for these dates, December 13 – 14, 2026](https://www.expedia.com/Hotel-Search?regionId=553248635975849120&startDate=2026-12-13&endDate=2026-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

[View in a map](https://www.expedia.com/Hotel-Search?regionId=553248635975849120&stayLength=1&daysInFuture=30&pwaOverlay=map)

## Our top choices for San Isidro hotels

### [1\. Vera Eco-Resort](https://www.expedia.com/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information)

![A spacious bedroom with a large bed, two bedside tables, and a view of a green landscape through a balcony.](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/aef1bb54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

- Location: San Ramon
- Guest rating: 8.4/10 (Very good, 5 reviews)
- Price: $65 nightly, $76 total, Dec 7 - Dec 8, Total with taxes and fees
- Review: This place is amazing!!!! The staff is super friendly and the location is beautiful., by Gabriela

### [2\. City Express by Marriott Esteli](https://www.expedia.com/Esteli-Hotels-Hotel-Hex-Esteli.h6975392.Hotel-Information)

![A modern interior with seating areas, a reception desk, and a snack vending machine.](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/636c6300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Esteli
- Guest rating: 8.4/10 (Very good, 224 reviews)
- Price: $70 nightly, $80 total, Nov 15 - Nov 16, Total with taxes and fees
- Review: Her exceptional service. The quality of the food significantly enhanced the experience., by Gelis, August 16th, 2026

### [3\. H & R Ranch Resort](https://www.expedia.com/Esteli-Hotels-H-R-Ranch-Resort.h95048999.Hotel-Information)

![A stone-tiled patio with a view of lush green hills and a misty valley.](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/61ae0723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Esteli
- Guest rating: 8.2/10 (Very good, 37 reviews)
- Price: $66 nightly, $78 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: We enjoyed horse rides got massages. Polite very accommodating., by Tania, June 19th, 2026

### [4\. Montebrisa Boutique B&B](https://www.expedia.com/Matagalpa-Hotels-Montebrisa-Boutique-BB.h36746289.Hotel-Information)

![A spacious indoor area with two rocking chairs, a ceiling fan, and a view of lush greenery outside.](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/485f5871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Matagalpa
- Guest rating: 9.2/10 (Wonderful, 55 reviews)
- Price: $90 nightly, $104 total, Nov 14 - Nov 15, Total with taxes and fees
- Review: Montebrisa B B was a beautiful property. The Owner was very friendly helpful., by Lezlie, August 11th, 2026

### [5\. Hotel Los Altos Esteli](https://www.expedia.com/Esteli-Hotels-Hotel-Los-Altos-Esteli.h10608128.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/11000000/10610000/10608200/10608128/5610bed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Esteli
- Guest rating: 8.4/10 (Very good, 119 reviews)
- Price: $65 nightly, $75 total, Dec 3 - Dec 4, Total with taxes and fees
- Review: Very nice , friendly and helpful staff., by Imani, August 20th, 2026

### [6\. Hotel Neblina](https://www.expedia.com/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information)

![A hotel room with two beds, a small table, and a balcony with a view.](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/6d5f6fa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Jinotega
- Guest rating: 7.6/10 (Good, 17 reviews)
- Price: $47 nightly, $54 total, Dec 14 - Dec 15, Total with taxes and fees
- Review: The hotel is in a very good position. You like comfort go upgrade., by Barry, September 29th, 2026

### [7\. Brisas Hotel](https://www.expedia.com/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information)

![A hotel hallway with a tiled floor, a vase with flowers on the left, and a red wall at the end.](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/9454e921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Matagalpa
- Guest rating: 9.8/10 (Exceptional, 21 reviews)
- Price: $57 nightly, $66 total, Nov 14 - Nov 15, Total with taxes and fees
- Review: Very nice accommodation, a good value, fríe staff., by Robert

### [8\. Hotel Vizcaino](https://www.expedia.com/Matagalpa-Hotels-Hotel-Vizcaino.h124518912.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/125000000/124520000/124519000/124518912/0139537c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Matagalpa
- Guest rating: 9/10 (Wonderful, 8 reviews)
- Price: $52 nightly, $60 total, Nov 14 - Nov 15, Total with taxes and fees
- Review: Heymer and staff was great. Safe location, parking available. Breakfast made to order., by Conny, 15 days ago

### [9\. Matagalpa la Tierra Land Of Dreams](https://www.expedia.com/MATAGALPA-LA-TIERRA-LAND-OF-DREAMS.h45603109.Hotel-Information)

![A covered outdoor area with a stone floor, potted plants, and a view of a mountainous landscape.](https://images.trvl-media.com/lodging/46000000/45610000/45603200/45603109/b50df01e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: San Ramon
- Guest rating: 2/10 (1 review)
- Review: No pude llegar al hotel y perdí mi deposito me fue imposible llegar en el vehículo al punto donde estaba el hotel,no pude disfrutar del lugar muy mal la ubicación del hotel, by Juan

### [10\. Hotel Casa Vinculos](https://www.expedia.com/Esteli-Hotels-Hotel-Casa-Vinculos.h36800438.Hotel-Information)

![A two-story building with a tiled roof and a storefront.](https://images.trvl-media.com/lodging/37000000/36810000/36800500/36800438/f0bd2a4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Esteli

### [11\. Hotel Bugambilias](https://www.expedia.com/Esteli-Hotels-Hotel-Bugambilias.h134676321.Hotel-Information)

![An indoor swimming pool with a glass ceiling, surrounded by stone walls and multiple balconies with plants.](https://images.trvl-media.com/lodging/135000000/134680000/134676400/134676321/ce8531a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Esteli
- Price: $65 nightly, $74 total, Nov 21 - Nov 22, Total with taxes and fees

### [12\. Hospedaje Coffee and Cocktails](https://www.expedia.com/Esteli-Hotels-Hospedaje-Coffee-And-Cocktails.h134571118.Hotel-Information)

![A hotel room with a bed, two pillows, a heart-shaped throw, and a remote control.](https://images.trvl-media.com/lodging/135000000/134580000/134571200/134571118/01d170f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Esteli

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://www.expedia.com/Hotel-Search?startDate=2026-11-27&endDate=2026-11-28&regionId=553248635975849120&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top San Isidro Hotel Reviews

### [Brisas Hotel](https://www.expedia.com/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information)

![A hotel hallway with a tiled floor, a vase with flowers on the left, and a red wall at the end.](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/9454e921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: clinica Santa Fe 75 varas este, Matagalpa, MATAGALPA, 10000, NI
- Location: Matagalpa
- Star rating: 2.5/5
- Guest rating: 9.8/10 (21 reviews)
- Review: Excelente estadía, buen servicio…, by Lesther, August 10, 2026, rated 10/10 Excellent

### [City Express by Marriott Esteli](https://www.expedia.com/Esteli-Hotels-Hotel-Hex-Esteli.h6975392.Hotel-Information)

![A modern interior with seating areas, a reception desk, and a snack vending machine.](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/636c6300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Km 149 Carretera Panamericana, Esteli, NI
- Location: Esteli
- Star rating: 3/5
- Guest rating: 8.4/10 (224 reviews)
- Review: Very knowledgeable bilingual, friendly staff. Rooms were decent size, newer, a/c, nice bath, cable TV and wifi throughout building (not just in lobby!) Comfortable, clean beds with nice pillows. Security 24 hours - free parking - cameras throughout building. Felt very safe. Good location on main strip - easy to locate. Situated next to a nice, new mall. Highly recommend - we will come back!, by Mike, August 24, 2014, rated 10/10 Excellent

### [Hotel Los Altos Esteli](https://www.expedia.com/Esteli-Hotels-Hotel-Los-Altos-Esteli.h10608128.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/11000000/10610000/10608200/10608128/5610bed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Calle transversal #13, Esteli, Esteli, 31000, NI
- Location: Esteli
- Star rating: 3/5
- Guest rating: 8.4/10 (119 reviews)
- Review: Clean, quite and confortable, friendly staff… only downside was hot water was not available at all times, by MARTHA, August 28, 2021, rated 10/10 Excellent

### [Montebrisa Boutique B&B](https://www.expedia.com/Matagalpa-Hotels-Montebrisa-Boutique-BB.h36746289.Hotel-Information)

![A spacious indoor area with two rocking chairs, a ceiling fan, and a view of lush greenery outside.](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/485f5871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Del Parque Morazán, 3 Cuadras al Este, Matagalpa, Matagalpa, NI
- Location: Matagalpa
- Star rating: 3.5/5
- Guest rating: 9.2/10 (55 reviews)
- Review: Great little hotel, very comfortable, quiet, clean, appointed., by Jason, January 13, 2022, rated 10/10 Excellent

### [Hotel Vizcaino](https://www.expedia.com/Matagalpa-Hotels-Hotel-Vizcaino.h124518912.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/125000000/124520000/124519000/124518912/0139537c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Iglesia de Guadalupe 1 1/2 al sur, Matagalpa, matagalpa, 61000, NI
- Location: Matagalpa
- Star rating: 3/5
- Guest rating: 9/10 (8 reviews)
- Review: Heymer and staff was great. Safe location, parking available. Breakfast made to order. Wheelchair accessible., by Conny, October 28, 2026, rated 10/10 Excellent

### [H & R Ranch Resort](https://www.expedia.com/Esteli-Hotels-H-R-Ranch-Resort.h95048999.Hotel-Information)

![A stone-tiled patio with a view of lush green hills and a misty valley.](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/61ae0723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Highway 49, 14 Kilometers from Esteli, Esteli, Esteli Department, NI
- Location: Esteli
- Star rating: 3/5
- Guest rating: 8.2/10 (37 reviews)
- Review: We had an amazing stay! We loved the meals at the restaurant & the ambiance as well. Beautiful place. The staff was attentive, polite & very accommodating. We enjoyed horse rides & got massages as well. The views from the cabins are amazing! Do be prepared for mosquitoes at night. Unfortunately we are sensitive & the bugs love our blood so we left with many bug bites. Yet we would do it all over again! 💛, by Tania, June 19, 2026, rated 10/10 Excellent

### [Vera Eco-Resort](https://www.expedia.com/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information)

![A spacious bedroom with a large bed, two bedside tables, and a view of a green landscape through a balcony.](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/aef1bb54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Vera Eco-Resort, San Ramon, Matagalpa, NI
- Location: San Ramon
- Star rating: 2.5/5
- Guest rating: 8.4/10 (5 reviews)
- Review: Had an excellent week at the resort. If you need a quiet, relaxing break this is the place to go. There are several kilometers of hiking trails. You can also do horseback riding and be guided through the coffee making process. The rooms are comfortable and clean. Hot water is dependable. Most units have amazing views. The staff are eager to help you enjoy your stay. Especially Stanley, who is a master at the hospitality profession., by Mark, January 1, 2025, rated 10/10 Excellent

### [Hotel Neblina](https://www.expedia.com/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information)

![A hotel room with two beds, a small table, and a balcony with a view.](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/6d5f6fa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Del Restaurante Tip Top 1 Cuadra Al Sur, Jinotega, Jinotega, 65000, NI
- Location: Jinotega
- Star rating: 2.5/5
- Guest rating: 7.6/10 (17 reviews)
- Review: Lugar céntrico accesible , con estacionamiento Muy limpio y personal amable, by German, September 28, 2026, rated 10/10 Excellent

### [Hotel Fountain Blue](https://www.expedia.com/Matagalpa-Hotels-Hotel-Fountain-Blue.h133372681.Hotel-Information)

![A spacious room with a wooden ceiling, a sofa, a chair, a desk, and a large window with a view of greenery.](https://images.trvl-media.com/lodging/134000000/133380000/133372700/133372681/0b22a917.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Matagalpa
- Review: Muy bien la estadia en el hotel, by Jose, August 1, 2026, rated 8/10 Good

## Frequently Asked Questions

### When is the best time to go to San Isidro?

The best time to go to San Isidro is during the dry season, which generally runs from November to April.

During these months, you'll experience pleasant, sunny weather with lower humidity, making it ideal for exploring the coffee plantations and outdoor activities around the region. The roads are also in their best condition during the dry season, which is helpful for navigating the rural areas surrounding San Isidro.

For travelers interested in a comfortable and stress-free visit, avoiding the rainy season (May to October) is recommended.

### Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in San Isidro.

### How much is the nightly rate at a San Isidro hotel?

Prices for hotels in San Isidro often vary, but you can find a great deal from $45 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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