San Isidro Vacations from $782

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Your San Isidro Vacation

Take the hassle out of organizing your next great adventure with a San Isidro vacation package. Whether you're here for its landmarks, food or something else, this city offers endless possibilities for fun. During your trip to San Isidro, give yourself plenty of time for sightseeing. An excellent place to begin exploring is Leonidas Proano Sports Center. Whatever your travel plans or the size of your budget, organizing your ultimate tailored San Isidro vacation is a piece of cake with Expedia.

The Latest San Isidro Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Dec 30 - Jan 4

    Hotel Patio Andaluz + Flight

    Quito Historic Center
    5 nights
    4.0 star property
    9.4/10 - Exceptional (502 reviews)
    "Nice, clean and pleasant hotel but be aware there is no lift and unless you get a room on the ground floor you will have to use the stars, go not great for people with mobility problems"
    Reviewed October 29, 2026
    Roundtrip • San Juan (SJU) - Quito (UIO)
    SJU - UIO • 1 stop UIO - SJU • 1 stop
    $1,108
    $782
    per traveler
    found 1 day ago
    Hotel Patio Andaluz
  • Jan 14 - Jan 18

    Hotel Mama Cuchara by Art Hotels Ecuador + Flight

    Quito Historic Center
    4 nights
    4.5 star property
    10/10 - Exceptional (41 reviews)
    Roundtrip • New York (EWR) - Quito (UIO)
    JFK - UIO • 1 stop UIO - EWR • 2 stops
    $1,600
    $1,116
    per traveler
    found 1 day ago
    Hotel Mama Cuchara by Art Hotels Ecuador
  • Feb 4 - Feb 8

    Illa Experience Hotel + Flight

    Quito Historic Center
    4 nights
    4.5 star property
    9.6/10 - Exceptional (47 reviews)
    "Hotel was like a jig saw puzzle with lots of stairways and areas. Still had construction going on. Rooms were very nice but no privacy unless you close your curtains. Room safes did not work in either of our rooms. You cannot flush toilet paper due to old pipes. Area did not feel very safe but we did not need to leave the hotel without a guide since the dining in the hotel was great. Overall I would recommend this hotel. "
    Reviewed April 9, 2026
    Roundtrip • New York (JFK) - Quito (UIO)
    JFK - UIO • Nonstop UIO - JFK • 1 stop
    $2,629
    $1,835
    per traveler
    found 1 day ago
    Illa Experience Hotel
  • Dec 30 - Jan 5

    Hotel Río Guayas by Art Hotels Ecuador + Flight

    Las Peñas
    6 nights
    4.0 star property
    10/10 - Exceptional (6 reviews)
    Roundtrip • New York (EWR) - Guayaquil (GYE)
    EWR - GYE • 1 stop GYE - EWR • 2 stops
    $2,987
    $2,087
    per traveler
    found 1 day ago
    Hotel Río Guayas by Art Hotels Ecuador
  • Jan 14 - Jan 18

    GO Quito Hotel + Flight

    Batán Grande
    4 nights
    5.0 star property
    9.6/10 - Exceptional (265 reviews)
    "Everything about my hotel stay was perfect! The service, cleanliness, atmosphere, and overall experience exceeded my expectations. I couldn't have asked for a better stay"
    Reviewed November 9, 2026
    Roundtrip • New York (EWR) - Quito (UIO)
    JFK - UIO • 1 stop UIO - EWR • 2 stops
    $1,566
    $1,124
    per traveler
    found 1 day ago
    GO Quito Hotel

San Isidro Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a San Isidro vacation package cost?

You can grab a vacation package to this top destination from $782 on Expedia. However, how much your vacation to San Isidro costs will depend on the length of stay, hotel choice and season.

What are the cheapest months to go to San Isidro?

If you're hoping to snag a cheap San Isidro vacation package, consider traveling in February, June and December. You'll generally find lower prices on flights and hotels during these months — ideal for a budget-friendly getaway.

How many days is enough for San Isidro?

With a well-organized travel plan, you can easily hit the most popular San Isidro sights in a few days. But if you'd like to discover hidden gems or go on day trips, think about booking your San Isidro vacation for longer.

How to find the best San Isidro package deals?

Use Expedia's handy filters to help you find some unbeatable San Isidro package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or browse for San Isidro package deals in the off-season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to book your vacation package well in advance.

Is it cheaper to book a San Isidro vacation as a package?

An Expedia vacation package could save you hundreds of dollars when compared to booking accommodations and flights separately. Better still, you can customize your San Isidro trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.

When to book a vacation package to San Isidro?

Enjoy incredible bargains by reserving your flights ahead of time with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for a spur-of-the-moment San Isidro vacation.

Does Expedia offer Book Now, Pay Later San Isidro vacation packages?

Secure your perfect trip to San Isidro with our Book Now, Pay Later vacations. There's no need to save up or wait for your next paycheck — we've joined forces with online lender Affirm to offer you flexibility with your finances. Our vacation packages with payment plans allow you to spread the total cost across 3, 6 or 12 months. With no late payment fees or extra charges, it's easy to stay on budget and snag great deals while they last.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.