San Luis Vacations from $590

Book a Hotel + Flight or Car together to unlock savings

Your San Luis Vacation

Take away the hard part of planning your next exciting adventure with a San Luis vacation package. Whether you've come for its cuisine, history, art or something else, you'll find countless exciting experiences to delve into. Wondering what to see or do first during your trip to San Luis? Head for famous attractions like Cocopah Museum. Stop daydreaming and start adventuring. Check out the many options on Expedia today and finally put your San Luis vacation plans in motion!

The Latest San Luis vacation packages

Price found within the past 48 hours. Click for updated prices.
OYO Hotel Yuma AZ - I-8/US-95
Cocopah Resort And Conference Center
Residence Inn By Marriott Yuma
Homewood Suites by Hilton Yuma
Historic Coronado Motor Hotel by OYO
Don't see what you're looking for?
See all available trips from Columbus to San Luis
View all trips

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.

San Luis Hotel Deals

La Fuente Inn & Suites

La Fuente Inn & Suites

3 out of 5
1513 E 16th St Yuma AZ
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $120 total per night from Dec 5 to Dec 6
$120 total
Dec 5 - Dec 6
Total with taxes and fees
9.2/10 Wonderful! (2,121 reviews)
In general everything was in good working order

Reviewed on Nov 29, 2025

La Fuente Inn & Suites
Quality Inn & Suites Yuma

Quality Inn & Suites Yuma

2.5 out of 5
1691 S Riley Ave Yuma AZ
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Dec 7 to Dec 8
$65 total
Dec 7 - Dec 8
Total with taxes and fees
8.4/10 Very Good! (1,044 reviews)
Room was okay, clean. Property is near town center and near the highway and interstate

Reviewed on Nov 26, 2025

Quality Inn & Suites Yuma
Motel 6 Yuma, AZ - East

Motel 6 Yuma, AZ - East

2 out of 5
1445 E 16th St Yuma AZ
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Dec 4 to Dec 5
$70 total
Dec 4 - Dec 5
Total with taxes and fees
7.8/10 Good! (1,048 reviews)
It was ok

Reviewed on Nov 26, 2025

Motel 6 Yuma, AZ - East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Luis Vacation Packages

San Luis Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Yuma Intl. Airport (YUM)
Population
31,500
Top Sights
Saihati Camel Farm and Cocopah Museum

More vacations you might like

Frequently asked questions

How much does a San Luis vacation package cost?
You'll find cheap prices from $590 on Expedia for your San Luis escape. However, a range of factors like the hotel choice, length of stay and season will influence how much your vacation to San Luis costs.
What are the cheapest months to go to San Luis?
June, July and December are great times to look for cheap San Luis vacation packages. Opting to travel in less busy months means you can usually find better prices on flights and hotels.
How many days is enough for San Luis?
With a well-organized travel plan, you can easily visit the top San Luis sights in a few days. But if you prefer to venture off the beaten track or take day trips, think about booking your San Luis vacation for longer.
How to find the best San Luis package deals?
Landing a cheap San Luis package deal is a breeze with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget range, apply a few filters and browse what's available. You can fine-tune your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most pocket-friendly San Luis package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a San Luis vacation as a package?
You can enjoy significant savings on your next San Luis getaway by booking a personalized vacation package. Click on the "Package" heading, then enter your destination and travel dates to view the best flight and hotel prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to San Luis?
Score amazing discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for an impromptu San Luis trip.
Does Expedia offer Book Now, Pay Later San Luis vacation packages?
If you're like us, you love traveling the world but don't love the big price tag that can sometimes come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the cost of your San Luis trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.